1,721,017 research outputs found

    Keratoacanthoma arising after site injection infection of cosmetic collagen filler

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    INTRODUCTION: Over one million treatments in more than 40 countries have been administered Zyplast implants. Infections at collagen implant sites have occurred in fewer than one per thousand treated patients. PRESENTATION OF CASE: We present a case report of a 27-year-old man; he developed a severe granulomatous reaction in the site of resolvable collagen filler injection Zyplast, and one month later developed a cutaneous nodular lesion. Histological examination of the lesion revealed Keratoacanthoma (KA) with surgical margins free of tumor. We performed two surgical corrections within a period of six months on multiple hypertrophic skin scars of the face. Two years after the last excision, the patient continued to be free of any recurrence. DISCUSSION: Keratoacanthoma (KA) is a benign skin tumor with a quick growth pattern but may regress spontaneously. Though the exact etiology of KA is uncertain, it is found to be more frequent in elderly people, on photo-exposed skin areas and cutaneous infection site. Bovine collagen intradermal injections, though catabolized over the time in the patient, can raise several complications already described in technical literature, but we want underline that cutaneous infection near filler injection site can develope KA as described in our case report. CONCLUSION: KA must be considered as a new local unforeseeable complication of bovine collagen injection to fill facial soft tissue when occurred a face cutaneous infection

    The use of liquid silicone gel in the treatment of hypertrophic scars and keloids

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    Actually silicone gel and silicone occlusive sheeting are the most useful and effective treatment for hypertrophic scars, surgical and traumatic. Moreover it was recommended also in the treatment of minor keloid in association with corticosteroid intralesional infiltration. Unfortunately, we incurred in some problems: maceration, rashes, itching and infection. Moreover not all patients were able to tolerate the plate, especially in children and in some anatomical region as the face, decolleté where it's not easy to dress for social, psychological and aesthetic obvious reasons. In other anatomical region it's difficult to obtain an adequate compression and occlusion of scar. To overcome such problems of applying silicone gel sheeting we wanted to test the using of liquid silicone gel (LSG) in the treatment of 36 linear hypertrophic scars (HS group) and 12 minor keloid (KS group) in alternative to silicone gel sheeting or plate. Objective parameters (volume, thickness and colour) and subjective complaints of pain, and itching sensation were examined on a scale of 0 to 3 (a low score was better), were made when the therapy started and after 30, 90 and 180 days of follow up. After 90 days of treatment with silicone gel alone (two application daily) the HS group showed a significant improvement in volume, redness and hardness

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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