1,355,177 research outputs found

    Considerazioni in merito al rapporto tra mediazione e processo alla luce del decreto legislativo n. 28/2010

    No full text
    In the occasion of the approval of the italian discipline of mediation, the author develops in this paper an accurate analysis of the nature of the mediation activity, comparing it with the activity of judgement. Particularly, the author highlights the difference between the purpose of composition of the opposte interests of the parties, typical of mediation, and the purpose of adjudication according to the law, typical of judgment in the civil law systems, and analyzes the differences between the settlement concluding a mediation and the sentence concluding a judicial proceeding

    I limiti soggettivi di efficacia della clausola compromissoria inserita negli statuti societari

    No full text
    In this essay, the author examines the borders of effectiveness of the arbitral clause included in articles of association, considering particularly the special discipline of art. 34 d.lgs. 5/2003, which affirms its binding towards all partners, also those who have not negotiated the statute or memorandum of association and towards directors, liquidators and inspectors of the companies. The author remembers that in order of effectiveness of the arbitral clause a specific approval is considered as necessary by the largest part of the doctrine and jurisprudence, and that the consent of the parties is the foundation of arbitration and of its constitutional legitimacy; so it cannot be replaced by a simple legal prevision, without arousing doubts of illegitimacy and invalidity of the clause. Consequently, it is necessary that the effects affirmed by the indicated legal disposition correspond to the will of the parties, according to general civil law. In this perspective, the author examines the special rules of formation of the collettive will, and concludes in the sense that they are not applicable to the arbitral clause without determinating the violation of several rules of the Italian Constitution

    Laparoscopic fowler-stephens orchidopexy for intra-abdominal cryptorchid testis: A single institution experience

    No full text
    Fowler-Stephens Laparoscopic Orchiopexy (FSLO) permits the mobilization of Intra-Abdominal Testis (IAT) to the scrotal position after spermatic vessel ligation. We reported our experience of FSLO for IAT. The charts of all boys who underwent a FSLO were retro-spectively reviewed. Data were analysed for demographic data, pro-cedure, complications and follow-up results. From January 2008 to June 2016, 160 laparoscopies for Non Palpable Testis (NPT) were performed at a mean age of 3,2 years. 61% of patients had a right NPT, while 6% were bilateral. In 64 cases, an IAT was found: 20 were managed by FSLO with a two-stage procedure in 11 patients. There were no differences in hospitalisations; one patient had a pro-longed ileus. Follow-up ranged from 1 to 8 years. Of the 20 patients who underwent FSLO, testicular atrophy developed in three; the remaining testes were in the scrotal position, with normal consisten-cy. FSLO was applied in 31% of IAT. The overall success rate of the technique was 85 %. The percentage of atrophy associated after spermatic vessels interruption appears to provide a good chance of testicular survival

    Antinociceptive and behavioral effects of synthetic deltorphin analogs

    No full text
    A possible correlation of behavioral, antinociceptive and cataleptic responses with central delta- and mu-opioid receptor stimulation was tested for in the rat by i.c.v. injections of some synthetic deltorphin analogs. At doses ranging from 0.1 to 3.0 nmol/rat, the selective delta-opioid receptor agonist, [D-Ala(2),Glu(4)]deltorphin (Tyr-D-Ala-Phe-Glu-Val-Val-Gly-NH2), induced a dose-dependent stereotyped pattern of locomotor activity, reaching the maximum in the first 30 min; doses higher than 30 nmol induced early and fleeting antinociception. The replacement of Glu(4) by Gly, Ala, Val, His or Asn yielded peptides with a lower delta-selectivity because of a gain in mu-affinity. [D-Ala(2),Ala(4)]deltorphin (0.14-4.0 nmol) induced negligible behavioral stimulation but a rapidly appearing and long-lasting analgesia and catalepsy. The other four synthetic peptides induced biphasic effects: low dosages stimulated locomotion whereas higher doses initially suppressed, then increased locomotor activity. At doses ranging from 1 to 70 nmol all the peptides induced analgesia and catalepsy. In experiments examining the locomotor and antinociceptive effects induced by 14 nmol of [D-Ala(2),Gly(4)]deltorphin in rats pretreated with mu and delta antagonists, the non-selective mu-opioid receptor antagonist, naloxone (1 mg/kg i.p.), reduced analgesia and abolished the initial hypolocomotion. The delta-selective antagonist, naltrindole (10 mg/kg i.p.), abolished locomotor activity without affecting analgesia. The mu(1)-selective antagonist, naloxonazine (10 mg/kg i.v.), seemed to prolong analgesia and immobility. Hence this peptide appears to activate, in addition to delta-receptors, mainly the opioid receptor mu(2)-subtype, which mediates catalepsy in the rat. We suggest that the mu(2)- and delta-opioid receptors of the rat brain modulate locomotor behavior by activating functionally opposed responses. [D-Ala(2),Ala(4)]deltorphin had an antinociceptive and cataleptic potency higher than would have been expected from its mu-affinity. A possible explanation might be a mu/delta-opioid receptor interaction

    Nerve Stimulator–Guided Sciatic-Femoral Block in Pet Rabbits (Oryctolagus cuniculus) Undergoing Hind Limb Surgery: A Case Series

    No full text
    This article describes the clinical applicability of a nerve stimulator–guided technique, previously described in dogs, to block the sciatic and the femoral nerves in 4 pet rabbits (Oryctolagus cuniculus) undergoing hind limb surgeries. Preanesthetic intramuscular doses of medetomidine (0.08 mg/kg), ketamine (15 mg/kg), and buprenorphine (0.03 mg/kg) were administered to the rabbit patients. The rabbits were intubated and general anesthesia was maintained using isoflurane in oxygen. The sciatic-femoral nerve block was performed with 2% lidocaine at a volume of 0.05 mL/kg/nerve. Sciatic-femoral block was feasible in rabbits, and the motoric responses following electrical stimulation of both nerves were consistent with those reported in dogs after successful nerve location. Iatrogenic complications, namely nerve damage and local anesthetic toxicity, did not occur. Based on these results, the authors conclude that the sciatic-femoral nerve block described in dogs can be safely performed in rabbits. Clinical trials are required to assess the analgesic efficacy of the combined sciatic-femoral nerve block in rabbits as a part of multimodal pain management
    corecore