112 research outputs found
AHC interview with Ruth B. Mandel
No full textMay 31, 2012Ruth B. Mandel was born Ruth Blumenstock in Vienna, Austria.Austrian Heritage CollectionRuth B. Mandel is the author of the book 'Jewish women in politics'.Digital recordin
Long-term follow up of AHC
Get PDFAlternating hemiplegia of childhood (AHC) is a rare neurological disease mainly caused by mutations in the ATP1A3 gene and showing varied clinical severity according to genotype. Patients with a p.Gly755Ser (p.G755S) mutation, one of minor genotypes for AHC, were recently described as having a mild phenotype, although their long-term outcomes are still unclear due to the lack of long-term follow up. Here, we demonstrate the full clinical course of a 43-year-old female AHC patient with p.G755S mutation. Although her motor dysfunction had been relatively mild into her 30 s, she showed a subsequent severe aggravation of symptoms that left her bedridden, concomitant with a recent recurrence of seizure status. The seizures were refractory to anti-epileptic drugs, but administration of flunarizine improved seizures and the paralysis. Our case suggests that the phenotype of AHC with p.G755S mutation is not necessarily mild, despite such a presentation during the patient's younger years
AHC interview with Peter Spielberg
No full textOctober 19, 2010Peter Spielberg was born on July 2, 1929 in Vienna as the son of Heinrich (Henry) Spielberg and Erna née Kulka. The family left Vienna in March 1939 for Czechoslovakia and immigrated to the United States on August 15, 1939. He studied at City College of New York and at New York University and finished his doctorate (Ph.D.) at the University of Buffalo. He taught English at Brooklyn College and is the author of several books of fiction
AHC Interview with George Alfred Kemeny
No full textGeorge Alfred Kemeny was born in Vienna on May 10, 1925. He lived with his family at Kaulbuchstrasse 20 in the 12th Viennese district. He fled from the Nazis on August 8, 1938 to former Czechoslovakia (Brno and Prague), then to Paris. In late 1938, he went to Havana, Cuba and left again after 2 years for Pittsburgh, Pennsylvania. He later joined the United States Army Infantry (military police) from December 1943 to February 1946. He went to school in Pittburgh at Carnegie Institute of Technology, from 1946 to 1948, and received a Bachelor of Science in electronic engineering. He then moved on to the University of Pittsburgh for a Master of Science. He worked as an engineer, manager, art appraiser, and author ("Tiffany-Desks Treasures"). He still lives in Pittsburgh, Pennsylvania
Molecular characterization and phylogenetic study of coxsackievirus A24v causing outbreaks of acute hemorrhagic conjunctivitis (AHC) in Brazil.
No full textBACKGROUND: Coxsackievirus A24 variant (CA24v) is the most prevalent viral pathogen associated with acute hemorrhagic conjunctivitis (AHC) outbreaks. Sixteen years after its first outbreak in Brazil, this agent reemerged in 2003 in Brazil, spread to nearly all states and caused outbreaks until 2005. In 2009, a new outbreak occurred in the northeast region of the country. In this study, we performed a viral isolation in cell culture and characterized clinical samples collected from patients presenting symptoms during the outbreak of 2005 in Vitória, Espírito Santo State (ES) and the outbreak of 2009 in Recife, Pernambuco State (PE). We also performed a phylogenetic analysis of worldwide strains and all meaningful Brazilian isolates since 2003. METHODS AND FINDINGS: Sterile cotton swabs were used to collect eye discharges, and all 210 clinical samples were used to inoculate cell cultures. Cytopathic effects in HEp-2 cells were seen in 58 of 180 (32%) samples from Vitória and 3 of 30 (10%) samples from Recife. Phylogenetic analysis based on a fragment of the VP1 and 3C gene revealed that the CA24v causing outbreaks in Brazil during the years 2003, 2004 and 2005 evolved from Asian isolates that had caused the South Korean outbreak of AHC during the summer of 2002. However, the 2009 outbreak of AHC in Pernambuco was originated from the reintroduction of a new CA24v strain that was circulating during 2007 in Asia, where CA24v outbreaks has been continuously reported since 1970. CONCLUSIONS: This study is the first phylogenetic analysis of AHC outbreaks caused by CA24v in Brazil. The results showed that Asian strains of CA24v were responsible for the outbreaks since 1987 and were independently introduced to Brazil in 2003 and 2009. Phylogenetic analysis of complete VP1 gene is a useful tool for studying the epidemiology of enteroviruses associated with outbreaks
TRANSPORT-PROPERTIES OF SOLITONS
Get PDFWe calculate in this article the transport coefficients which characterize the dynamics of solitons in quantum field theory using the methods of dissipative quantum systems. We show how the damping and diffusion coefficients of solitonlike excitations can be calculated using the integral functional formalism. The model obtained in this article has features which cannot be obtained in the standard models of dissipation in quantum mechanics.4854037404
Mining a Web citation database for author co-citation analysis
No full textAuthor co-citation analysis (ACA) has been widely used in bibliometrics as an analytical method in analyzing the intellectual structure of science studies. It can be used to identify authors fromthe same or similar research fields. However, such analysis method relies heavily on statistical tools to perform the analysis and requires human interpretation. Web Citation Database is a data warehouse used for storing citation indices of Web publications. In this paper, we propose a mining process to automate the ACA based on the Web Citation Database. The mining process uses agglomerative hierarchical clustering (AHC) as the mining technique for author clustering and multidimensional scaling (MDS) for displaying author cluster maps. The clustering results and author cluster map have been incorporated into a citation-base
On quantum transmission of a system with internal degrees of freedom
No full textWe study the quantum tunnelling of a complex object of which only part is coupled to an external potential (the potential barrier), We treat this problem as the tunnelling of a particle (part of the system affected by the potential) linearly coupled to a ''heat bath'' (all of the remaining degrees of freedom) from the point of view of the wavefunction of the whole system, We obtain an effective scattering equation for this wavefunction which resembles the integral equation for the wavefunction of the particle in the absence of the bath, We show that the effect of the interaction is to renormalize the mass and the potential of the problem and that these new parameters can be solely described in terms of the spectral function of the excitations of the system.2094179529029
NEW MODEL FOR DISSIPATION IN QUANTUM-MECHANICS
No full textWe propose a new model for studying dissipation in quantum-mechanical systems. The mechanism of dissipation is solely due to the scattering of the environment excitations by the particle of interest. We treat the problem via the functional integral formalism. It is shown that the model gives a damping parameter which is temperature dependent.67151960196
ALTERNATIVE APPROACH TO THE DYNAMICS OF POLARONS IN ONE DIMENSION
Get PDFWe developed a method based on functional integration to treat the dynamics of polarons in one-dimensional systems. We treat the acoustical and the optical case in a unified manner, showing their differences and similarities. The mobility and the diffusion coefficients are calculated in the Markovian approximation in the strong-coupling limit.46148858887
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