1,312 research outputs found
Problems of Termination of Legal Work Relationship on the Basis of Labor Law Section 101, Paragraph 1, Clauses 3, 4
No full textDace Tarasova savā rakstā pievērš uzmanību vairākām problēmām darba tiesisko attiecību regulējumā. Autore pēta darba tiesisko attiecību izbeigšanu, pamatojoties uz to, kad darbinieks, veicot darbu, rīkojies pretēji labiem tikumiem.Dace Tarasova in her article turns the attention to a series of problems in the regulation of legal employment relationship. The author studies the termination of legal employment relationship referring to the fact that an employee, while doing work, has acted contrary to the right virtues
Studying breaking of inverted emulsions with thermolysis purification TD 600
No full textTarasova G. I. Studying breaking of inverted emulsions with thermolysis purification TD600 / G. I. Tarasova, O. N. Shevaga, E. O. Gracheva // IOP Conf. Series: Materials Science and Engineering. - 2018. - Vol.327. - 032055.Currently, emulsions are used in many branches of industry and agriculture. It explains significant attention paid to issues in production, stabilization and breaking of emulsion. Besides, producing steady emulsions is of importance in many processes; the reverse problem, that of demulsification, is important as well in oil production and treatment of oil emulsion waste water. This paper studies the breaking (demulsification) of inverted emulsions
with the help of thermolysis purification TD600, produced by thermal modification of purification, a large-scale waste of the sugar industry
Establishing a proteomics-based monocyte assay to assess differential innate immune responses
No full textThe innate immune system represents the first line of organism defense. Monocytes and their derivatives, the macrophages, play a central role in this response. The monocyte response to various stimuli is complex and includes simultaneous activation in a variety of ways. The common methods currently used to estimate this response usually focus on one of the modes of activation. The aim of this thesis was to assess the possibility of designing an assay based on unbiased proteome analysis that would be capable of predicting the monocyte response to various challenges. The underlying hypothesis of the project was that the cell proteome response to different activating molecules would reflect the immunogenicity of these molecules. The assay is based on comparison between the proteomes of human monocytic THP-1 cells treated with a stimulus of interest and the ‘reference’ proteomes obtained from THP-1 cells treated with positive and negative controls. The study described in Paper I (Project 1) revealed two main types of monocyte responses and features of monocyte separation into adherent and non-adherent subpopulations. The first subpopulation differentiated into macrophages, while the second one was activated by cytokines according to the changes in their proteomes compared to the control cells. The Pam3CSK4 and PMA stimuli were concluded to be the best positive controls for pro-inflammatory activation and differentiation, respectively, among the tested nine treatments (Paper II, Project 2). Anti- cancer drugs with known mechanisms of action were chosen as positive controls for cell death (Paper III). The workflow of the assay was optimized and validated in Paper II (Project 2). The established assay was applied to identify the response of monocytes to peptide containing isoaspartate (Paper II, Project 3) and nanoparticles (Paper III, Project 3). The epidermal growth factor (EGF) peptide containing isoaspartate primed monocytes for differentiation but not for pro-inflammatory activation. The three studied nanoparticles induced distinct proteome signatures despite equivalent overall toxicity effect (induction of 50±10% cell death). The CdTe-NH2 nanoparticles induced the strongest response characterized by down-regulation of topoisomerases and similar to the effect of Camptothecin. The response to CuO nanoparticles included up-regulation of proteins involved in heat response. The gold nanoparticles showed the weakest response among the studied three nanoparticles and induced up-regulation of NF-κB and a number of proteins related to energy metabolism consistent with pro-inflammatory activation. The established and validated assay has several possibilities for extension as well as optimization for particular aims of the experiment. For instance, the identification of induced post- translational modifications upon stimulation can be performed (Paper IV, Project 4). Because of its versatility, robustness and specificity, this new assay is likely to find a niche among the more established immunological methods.List of scientific papersI. Tarasova N. K., Ytterberg A. J., Lundberg K., Zhang X.-M., Harris R. A., and Zubarev R. A. Proteomics reveals a role for attachment in monocyte differentiation into efficient pro-inflammatory macrophages. Journal of Proteome Research, 2015, 14 (9), pp. 3940-3947 https://doi.org/10.1021/acs.jproteome.5b00659 II. Tarasova N. K., Ytterberg A. J., Lundberg K., Zhang X.-M., Harris R. A., and Zubarev R. A. Establishing a Proteomics-based Monocyte Assay to Assess Differential Innate Immune Activation Responses. [Manuscript]III. Tarasova N. K., Ytterberg A. J., Chernobrovkin A., Zubarev R. A. Toxicity Effect of Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approach. [Manuscript]IV. Ytterberg A. J., Joshua V., Reynisdottir G., Tarasova N. K., Rutishauser D., Ossipova E., Haj Hensvold A., Eklund A., Sköld C. M., Grunewald J., Malmström V., Jakobsson P. J., Rönnelid J., Padyukov L., Zubarev R. A., Klareskog L., Catrina A. I. Shared immunological targets in the lungs and joints of patients with rheumatoid arthritis: identification and validation. Annals of the Rheumatic Diseases, 2015, 74 (9), pp. 1772-1777 https://doi.org/10.1136/annrheumdis-2013-204912 </p
Translation as a form of interliterary reception
No full textLiulka V., Tarasova N. Translation as a form of interliterary reception. Тенденції та перспективи розвитку науки і освіти в умовах глобалізації : матеріали міжнар. наук.-практ. інтернет-конф. Переяслав, 2023. Вип. 99. С. 304-306.Стаття присвячена перекладу як формі міжлітературної рецепції. Виділяються аспекти, які підкреслюють зв’язок між перекладом і міжлітературною рецепцією (ідіоми та фрази, культурні асоціації, традиції та ритуали, історичні та культурні алюзії); аспекти, які перекладачі враховують під час адаптації стилів і тонів (тональність, рівень формальності, художній стиль, культурні особливості, особливості текстового жанру). Зазначені декілька особливостей, пов’язаних із рецепцією літературних напрямів у перекладі: стилістичні особливості, форми вираження, теми та мотиви, культурний і часовий контекст, інтертекстуальніст
Translation as a form of interliterary reception
No full textLiulka V., Tarasova N. Translation as a form of interliterary reception. Тенденції та перспективи розвитку науки і освіти в умовах глобалізації : матеріали міжнар. наук.-практ. інтернет-конф. Переяслав, 2023. Вип. 99. С. 304-306.Стаття присвячена перекладу як формі міжлітературної рецепції. Виділяються аспекти, які підкреслюють зв’язок між перекладом і міжлітературною рецепцією (ідіоми та фрази, культурні асоціації, традиції та ритуали, історичні та культурні алюзії); аспекти, які перекладачі враховують під час адаптації стилів і тонів (тональність, рівень формальності, художній стиль, культурні особливості, особливості текстового жанру). Зазначені декілька особливостей, пов’язаних із рецепцією літературних напрямів у перекладі: стилістичні особливості, форми вираження, теми та мотиви, культурний і часовий контекст, інтертекстуальніст
Work with Linguistically Gifted Students During Foreign Language Course at Non-Language University
No full textГубайдуллина Альфия Гарайхановна, кандидат педагогических наук, доцент, доцент кафедры иностранных языков, Казанский федеральный университет, Елабужский институт, г. Елабуга, [email protected].
Тарасова Алина Андреевна, студент 2 курса, факультета филологии и истории, Казанский
федеральный университет, Елабужский институт, г. Елабуга, [email protected]. A.G. Gubaidullina, [email protected],
A.A. Tarasova, [email protected]
Kazan Federal University, Elabuga Institute, Elabuga, Russian FederationСтатья посвящена организации индивидуальной работы по иностранному языку с
лингвистически одаренными студентами-филологами младших курсов в Елабужском институте Казанского федерального университета. Охарактеризованы образовательные цели
и этапы работы одаренных студентов с художественным текстом. В качестве примера
представлена совместная работа преподавателя и студента по лингвистическому анализу
рассказа О. Генри «The Count and the Wedding Guest» («Черное платье»). В содержание
образования включены композиционные элементы короткого рассказа, стилистические
средства с их определениями и примерами на языке оригинала и в переводе на русский
язык, а также интерпретация текста, помогающая понять психологические и социальные
моменты рассказа. The article describes the individual work with the linguistically gifted first year students that
are philologists while studying a foreign language at Elabuga Institute of Kazan Federal University.
It provides the educational aims, stages of work with gifted students. The results of teacherstudent
cooperative work in linguistic analysis of O. Henry’s short story “The Count and the
Wedding Guest” was presented. The main compositional elements of a story (exposition, starting
point, rising action, climax, denouement) as well as the main stylistic devices used by the author
with their definitions, proved by the examples from the original English text and its Russian
translation have been included into the content. Some interpretation helping to understand sociological
and psychological aspects of the story can be found
Automated Extraction of Information From Texts of Scientific Publications: Insights Into HIV Treatment Strategies
No full textText analysis can help to identify named entities (NEs) of small molecules, proteins, and genes. Such data are very important for the analysis of molecular mechanisms of disease progression and development of new strategies for the treatment of various diseases and pathological conditions. The texts of publications represent a primary source of information, which is especially important to collect the data of the highest quality due to the immediate obtaining information, in comparison with databases. In our study, we aimed at the development and testing of an approach to the named entity recognition in the abstracts of publications. More specifically, we have developed and tested an algorithm based on the conditional random fields, which provides recognition of NEs of (i) genes and proteins and (ii) chemicals. Careful selection of abstracts strictly related to the subject of interest leads to the possibility of extracting the NEs strongly associated with the subject. To test the applicability of our approach, we have applied it for the extraction of (i) potential HIV inhibitors and (ii) a set of proteins and genes potentially responsible for viremic control in HIV-positive patients. The computational experiments performed provide the estimations of evaluating the accuracy of recognition of chemical NEs and proteins (genes). The precision of the chemical NEs recognition is over 0.91; recall is 0.86, and the F1-score (harmonic mean of precision and recall) is 0.89; the precision of recognition of proteins and genes names is over 0.86; recall is 0.83; while F1-score is above 0.85. Evaluation of the algorithm on two case studies related to HIV treatment confirms our suggestion about the possibility of extracting the NEs strongly relevant to (i) HIV inhibitors and (ii) a group of patients i.e., the group of HIV-positive individuals with an ability to maintain an undetectable HIV-1 viral load overtime in the absence of antiretroviral therapy. Analysis of the results obtained provides insights into the function of proteins that can be responsible for viremic control. Our study demonstrated the applicability of the developed approach for the extraction of useful data on HIV treatment. © Copyright © 2020 Biziukova, Tarasova, Ivanov and Poroikov
Construing of a female image in man's magazines published in Latvian and Russian
No full textJekaterīna Tarasova
„Sievietes tēla konstruēšana latviešu un krievu valodā iznākušos vīriešu žurnālos” Bakalaura darbs
Darba vadītāja: Docents Dr.sc.soc. Silva Seņkāne
Darba apjoms: 55 lappuses., 2 pielikumi, 2 attēli
Atslēgvārdi: realitāte, stereotipi, tēli, vīriešu žurnāli
Darbs sastāv no 7 daļām: Masu komunikācijas modeļi, Mediju realitātes sociāla konstruēšana, Tēli un stereotipi, Žurnālu auditorija, Sievietes tēls vīriešu žurnālos, Vīriešu žurnālu KLUBS un ПАТРОН analīze, Fokusgrupas.
Pētījuma mērķis: Noskaidrot sieviešu tēla konstruēšanās īpatnības latviešu un krievu valodā iznākošos vīriešu žurnālos KLUBS un ПАТРОН, atrast kopīgās un atšķirīgās iezīmes.Uzdevumi:
Raksturot vīriešu žurnālus KLUBS un ПАТРОН
Definēt jēdzienu “dzimuma stereotipi”;
Izpētīt, vai vīriešu žurnālu saturā parādās dzimuma stereotipi.
Analizēt, apkopot fokusgrupu intervijas rezultātus un noskaidrot auditorijas viedokli par dzimuma stereotipiem;
Pētījuma metodes: satura semiotiskā analīze, fokusgrupu metode.Teorētiskā daļā par pamatu izmantota akadēmiskā literatūra, žurnāla kā medija analīze, dzimuma stereotipu teorētiskai definēšanai. Kvalitatīvo pētījumu metožu pielietojums darbā palīdzēja iegūt personu un grupas attieksmi un viedokli, atklāja mūsdienu auditorijas attieksmi par darbā pētāmo jautājumu.Jekaterīna Tarasova
“Construing of a female image in man's magazines published in Latvian and Russian”
Bachelor Paper
Advisor: Docent Dr.sc.soc. Silva Seņkāne
Volume of paper is 55 pages, 2 appendices, 2 pictures
Key-words: reality, stereotypes, images, men’s magazines.
The paper consists of the 7 chapters: Models of Mass Communication, Social Formation of Media Reality, Images and Stereotypes, Audience of Magazines, Woman’s Image in Men’s Magazines, Analysis of Men’s Magazines KLUBS and PATRON, Focal Groups.
The goal of the research is to clarify the peculiarities of a woman’s image formation in magazines KLUBS and PATRON that are published in Latvian and Russian, to find common and different features.
The enabling objectives of the paper are:
To characterize KLUBS and PATRON magazines;
To define the notion of “sex stereotype”;
To investigate if the sex stereotypes appear in the content of men’s magazines;
To analyze, to summarize the results of focal group’s interviews and to clarify audience’s opinion about sex stereotypes;
The methods of research are semiotic analysis of content and the method of focal groups.
In the theoretical part the author uses academic literature as a basis, and the analysis of a magazine as a means of media, in order to define the sex stereotypes in theory. Use of qualitative methods in present paper helps to acquire attitude and opinion of persons and a group, discovers the attitude of contemporary audience toward the investigated matter
Sensory development of 3-4 years old children by working with fine motor skills
No full textDarba tēma: Sensorā attīstība 3-4 gadus veciem bērniem, darbojoties ar veidošanas materiāliem Darba autore: Jūlija Tarasova Darba veids: Kvalifikācijas darbs Darba vadītājs: Mg. paed., pasn. Ineta Aizporiete Pētījuma mērķis: pētīt 3-4 gadus vecu bērnu sensoro prasmju veicināšanas iespējas darbojoties ar veidošanas materiālu. Darbs sastāv: no ievada, 3 nodaļām, nobeiguma, izmantotas literatūras saraksta, 9 pielikumi. Darba apjoms: 73 lpp., 4 tabulas, 25 attēli, 59 literatūras avoti, 9 pielikumiem. Darba teorētiskajā daļā raksturota 3-4 gadus vecu bērnu vispārīgā attīstība, kā arī tieši sensorā attīstība. Analizēti veidošanas mērķi un uzdevumi pirmsskolā, veidošanas veidi, veidošanas nozīme bērnu sensorajā attīstībā. Darba pētnieciskajā daļā pēc izstrādātajiem kritērijiem novērotas 3-4 gadus vecu bērnu sensorās prasmes veidošanas nodarbībās. Veikta sākotnējā vērošana un atkārtotā vērošana pēc veiktās izmēģinājuma darbības. Tika veikta arī pirmsskolas skolotāju aptauja par pētāmo problēmu. Pēc veiktā pētījuma uz jautājumu:: Vai, izmantojot dažādus veidošanas materiālus, var veicināt 3 -4 gadus vecu bērnu sensoro attīstību? - var atbildēt apstiprinoši. Atslēgas vārdi: 3-4 gadus veci bērni, sensorā attīstība, tehnoloģiju mācību joma, veidošana.The theme of the work: Sensory development of 3-4 years old children by working with fine motor skills. The qualification paper author: Jūlija Tarasova Type of work: Qualification work The qualification paper supervisor: Master of Education: Ineta Aizporiete The goal of qualification paper: to study the development of sensory skills in children 3-4 years old when working with fine motor materials (using different activities). Structure: introduction: 3 chapters, conclusion, references, 9 appendices. The qualification paper consists of: 73 pages, 4 tables, 25 figures, 59 references, 9 appendices. The theoretical part of the work describes the general development of children 3-4 years old, as well as sensory development. The goals and objectives of education in preschool-age were analyzed, also the types of education and the role of education in the sensory development of children. In the research part of the work, according to the developed criteria, classes were held to develop sensory skills in children 3-4 years old. Initial observation and re-observation were made after the performed experimental activity of the children. A survey was also conducted among preschool teachers regarding the issue of the research. The question of qualification paper: Is it is possible to stimulate the sensory development of children 3-4 years old using various fine motor materials? - Yes, it is possible. Keywords: children 3-4 years old, sensory development, the field of technology, and fine motor skills
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