1,720,958 research outputs found
Movement related cortical potentials are corelated to neuropsychological tests in the assesment moderate alzheimer's disease and mild cognitive impairment
Alzheimer Hastalığı (AH) demansın en yaygın nedeni olan önemli bir toplum sorunu haline gelmiştir. AH, kesin tedavisi olmayan erken dönemde tanı konulduğunda seyrinin yavaşlatılabildiği bir hastalıktır. Hafif bilişsel bozukluk (HBB) bellek ve diğer kognitif yetilerin etkilenebildiği normal yaşlanma ile demans arasındaki ara bölge olarak tanımlanan klinik tablodur. Patolojik olarak erken AH bulguları saptanmıştır. Yılda ortalama % 15 oranında farklı türlerdeki demans sendromuna dönüşebilir. Günümüzde HBB ve AH'nın tanısında elektrofizyolojik incelemelerin kullanımı yapısal ve fonksiyonel görüntüleme yöntemlerinin yanında sınırlı kalmaktadır. Elektrofizyolojik incelemeler HBB ve AH'nin tanısında ve izleminde kullanılabilir. Devinime İlişkin Kortikal Potansiyeller (DİP) bu amaçla kullanılabilecek elektrofizyolojik testlerden biri olabilir. Bu çalışmada 20 HBB ve 20 AH tanılı hastada DİP kayıtlaması yapılmıştır. Elde edilen potansiyellerin latans ve amplitüt değerleri, 25 normal kontrol olgusunun latans ve amplitüt değerleri ile karşılaştırılmıştır Sonuç olarak AH, HBB ve kontrol grubu ile karşılaştırıldığında, DİP dalgası AH grubunda HBB grubuna göre, HBB grubunda da kontrol grubuna göre daha geç ortaya çıkmıştır. AH grubunda MP amplitüdü HBB ve kontrol grubuna göre düşük saptanmıştır. Bu çalışma ile DİP'in AH tanısında ve klinik izleminde; ayrıca HBB'nin AH'ye ilerlemesini gösterebilecek elektrofizyolojik test olarak kullanılabileceğini düşünüyoruz.Alzheimer disease (AD) is the most common cause of dementia and represents a major public health problem. There is no accurate treatment for AD at the time; however, the course of the disease can be significantly retarded with early diagnosis and treatment. Mild cognitive impairment (MCI) is determinating between normal aging and dementia, that affecting memory and partly other cognitive abilities. Early Alzheimer disease?s pathologic findings are determined. MCI can progress to different dementia syndromes %15 per year. Currently, the use of electrophysiological tests in the diagnosis of MCI and AD, has a limited value when compared to structural and functional imaging methods. Electrophysiologic tests can be used in diagnosis and following up of AD and MCI. Movement Related Cortical Potentials (MRCP) are the one of the electrophysiologic tests that can be used in this way. MRCP recording in 20 patient having MCI and AD had been done in this study. Obtained lateness and amplitüde values of potentials had been compared with lateness and amplitude values of the 25 normal control cases. At the end, when compared AD with HBB and control group, DIP wave of AD group to HBB group, HBB group to control group appeared later. Motor potentials amplitudes of the AD group were found smaller than MCI and control group We think that, MRCP can be used as a electrophysical test in diagnostic and clinical follow up of AD patients; and also can show MCI?s progress to AD
Movement related cortical potentials are corelated to neuropsychological tests in the assesment moderate alzheimer's disease and mild cognitive impairment
Alzheimer Hastalığı (AH) demansın en yaygın nedeni olan önemli bir toplum sorunu haline gelmiştir. AH, kesin tedavisi olmayan erken dönemde tanı konulduğunda seyrinin yavaşlatılabildiği bir hastalıktır. Hafif bilişsel bozukluk (HBB) bellek ve diğer kognitif yetilerin etkilenebildiği normal yaşlanma ile demans arasındaki ara bölge olarak tanımlanan klinik tablodur. Patolojik olarak erken AH bulguları saptanmıştır. Yılda ortalama % 15 oranında farklı türlerdeki demans sendromuna dönüşebilir. Günümüzde HBB ve AH'nın tanısında elektrofizyolojik incelemelerin kullanımı yapısal ve fonksiyonel görüntüleme yöntemlerinin yanında sınırlı kalmaktadır. Elektrofizyolojik incelemeler HBB ve AH'nin tanısında ve izleminde kullanılabilir. Devinime İlişkin Kortikal Potansiyeller (DİP) bu amaçla kullanılabilecek elektrofizyolojik testlerden biri olabilir.Bu çalışmada 20 HBB ve 20 AH tanılı hastada DİP kayıtlaması yapılmıştır. Elde edilen potansiyellerin latans ve amplitüt değerleri, 25 normal kontrol olgusunun latans ve amplitüt değerleri ile karşılaştırılmıştırSonuç olarak AH, HBB ve kontrol grubu ile karşılaştırıldığında, DİP dalgası AH grubunda HBB grubuna göre, HBB grubunda da kontrol grubuna göre daha geç ortaya çıkmıştır. AH grubunda MP amplitüdü HBB ve kontrol grubuna göre düşük saptanmıştır.Bu çalışma ile DİP'in AH tanısında ve klinik izleminde; ayrıca HBB'nin AH'ye ilerlemesini gösterebilecek elektrofizyolojik test olarak kullanılabileceğini düşünüyoruz.Anahtar Kelimeler: Alzheimer Hastalığı, Hafif Bilişsel Bozukluk, Devinime İlişkin Kortikal Potansiyel, Nöropsikolojik TestlerAlzheimer disease (AD) is the most common cause of dementia and represents a major public health problem. There is no accurate treatment for AD at the time; however, the course of the disease can be significantly retarded with early diagnosis and treatment. Mild cognitive impairment (MCI) is determinating between normal aging and dementia, that affecting memory and partly other cognitive abilities. Early Alzheimer disease?s pathologic findings are determined. MCI can progress to different dementia syndromes %15 per year. Currently, the use of electrophysiological tests in the diagnosis of MCI and AD, has a limited value when compared to structural and functional imaging methods. Electrophysiologic tests can be used in diagnosis and following up of AD and MCI. Movement Related Cortical Potentials (MRCP) are the one of the electrophysiologic tests that can be used in this way.MRCP recording in 20 patient having MCI and AD had been done in this study. Obtained lateness and amplitüde values of potentials had been compared with lateness and amplitude values of the 25 normal control cases.At the end, when compared AD with HBB and control group, DIP wave of AD group to HBB group, HBB group to control group appeared later. Motor potentials amplitudes of the AD group were found smaller than MCI and control groupWe think that, MRCP can be used as a electrophysical test in diagnostic and clinical follow up of AD patients; and also can show MCI?s progress to AD.Keywords:Alzheimer disease, mild cognitive impairment,movement related cortical potential, neuropsychological test
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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