1,720,954 research outputs found
Development, Validation and simultaneous estimation of Sulfamethoxazole and Trimethoprim by RP-HPLC Method
Get PDFThe straightforward, precise, accurate approach has been established for such simultaneous determination of a Sulfamethoxazole as well as Trimethoprim through oral dosage form. Chromatogram has been operate via inertsil ODS C185µm (4.6 x 250mm). Mobile phase comprising phosphate - buffered as well as acetonitrile with in proportion like 30:70 has been fired up thru section at such a rate of flow like 1ml/min. Buffer in use at pH 4.6, temperature has been retained there as ambient. Optimization frequency range such as Sulfamethoxazole as well as Trimethoprim has been 249nm. Time of retention like Sulfamethoxazole as well as trimethoprim have been did find of being 2.327min as well as 4.342min. A % purification like Sulfamethoxazole as well as Trimethoprim has been did find of being 100.6% as well as 101.3% including both. a stability studies parametric such as Sulfamethoxazole as well as Trimethoprim like theoretical plates as well as tailing element have been did find of being 1.3, 5117.5.as well as 1.4, 3877.3 a resolution has been did find of being 4.1.a linear relationship research such as Sulfamethoxazole as well as Trimethoprim has been present in range of concentrations like 20 ppm-100 ppm but also 10 ppm-50 ppm as well as coefficient of correlation (r2) has been did find of being 0.9999 as well as 0.9998, % average retrieval has been did find of about 99.96% as well as 99.75%, % RSD such as reproducibility was 0.31 as well as 0.38, % RSD such as medium precision has been 0.12 but also 0.15 including both. A precision research was accurate, robust as well as reproducible. LOD valuation has been 0.48 as well as 0.55, but also LOQ valuation has been 0.95 but also 1.10 including both
Formulation and Evaluation of Itraconazole Nanocapsules
Get PDFAn objective of a present research has been able to prepare as well as analyze Itraconazole Nanocapsules through using emulsion solvent evaporation method. Itraconazole has been overfilled of ethyl cellulose & hydroxypropyl methylcellulose Nanocapsules and that was able to prepare through emulsion solvent evaporation technique. The outcomes like Fourier transform infrared implied a steady identity like Itraconazole Nanocapsules filled as for ethyl cellulose Nanocapsules and then also absence like drug - excipient interplay. Compatibility research findings like FTIR & differential scanning have been used to start investigating that there's no incompatability inside the composition. A morphometric size of the particles like Itraconazole Nanocapsules has been done through SEM. Nanocapsules has been analyzed such as total composition codes has been f1 to f8. A % yield has been obtained to be 73.22% to 88.91%. Drug content has been 65.9 to 98.4%. A size of the particles like Nanocapsules 80 µm to 22 µm, drug entrapment efficiency has been 54.3% to 91.3 %, a drug loading capabilities has been 97.8% to 56.9%. A swellability studies has been 0.6 sec to 1.6 sec. in vitro dissolution studies like best formulation f8 has been did find of being 61.78%. An In-vitro drug dissolution obtained data has been equipped to numerous mathematical equations such like zero order, 1st order, higuchi matrix & korsmeyer peppas model. Itraconazole Nanocapsules continues to follow model having r2 value has been 0.937, 0.399, 0.899, 0.785 & m value has been 1593, 0.061, 11409, 2.560. The discharge of drug out from Nanocapsules increased up of about 45 mints. Itraconazole loaded as for ethyl cellulose & HPMC Nanocapsules have been able to prepare below optimum condition and it display great discharge characteristic features
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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