1,721,135 research outputs found
Ipomea hederacea Jacq.: A Medicinal Herb with Promising Health Benefits
No full textIpomea hederacea Jacq. (kaladana or ivy leaf morning-glory), a member of the family Convolvulaceae, is used primarily for its seeds and recognized for its medicinal properties, especially in Asian countries. This medicinal herb contains various valuable chemical constituents such as ecdysteriods, steroidal glycosides, aromatic acids, triterpenes, amino acids, organic acids, mineral elements and vitamins. A number of pharmacological properties such as diuretic, anthelmintic, blood purifier, deobstruent, laxative, carminative and anti-inflammatory actions have been ascribed to this plant, besides its use to treat abdominal diseases, fevers, headache and bronchitis. This review focuses on compositional, medicinal and therapeutic properties of this plant, as a potential sources of bioactive molecules for medicinal and nutraceutical applications
Antioxidant Activity of the Extracts of Some Cowpea (Vigna unguiculata (L) Walp.) Cultivars Commonly Consumed in Pakistan
No full textThe present investigation has been carried out to determine the antioxidant activity of the methanolic extracts obtained from four cultivars of cowpea (Vigna unguiculata (L) Walp.) seeds. Phenolic compounds present in the extracts showed the antioxidant and antiradical properties when investigated using a linoleic acid peroxidation model, FRAP, ORAC and TRAP assays, as well as DPPH, hydroxyl, nitric oxide and superoxide radical scavenging activity. The HPLC analysis of the cowpea extracts showed the presence of neochlorogenic acid, chlorogenic acid and caffeic acids. The results indicated that methanolic extract of the cowpea resembled in the aforementioned activities those from other leguminous seeds and pulses. Phenolic constituents contained in cowpea may have a future role as ingredients in the development of functional foods
Phytochemical and Biological Studies of Agave attenuata
No full textThe present study was conducted to examine various biological activities of a methanol extract of Agave attenuata leaves. GC-MS analysis of the n-hexane fraction from the extract revealed the presence of 31 compounds, with mono-2-ethylhexyl phthalate (11.37%), 1,2-benzenedicarboxylic acid (6.33%), n-docosane (6.30%) and eicosane (6.02%) as the major components. The leaves contained appreciable levels of total phenolic contents (10.541–39.35 GAE, mg/100 g) and total flavonoid contents (43.35–304.8 CE, mg/100 g). The extract and some of its fractions showed moderate antimicrobial effects. Leaves extract and fractions also exhibited a good antioxidant potential when measured by DPPH radical scavenging activity and inhibition of lipid peroxidation assays. The hemolytic effect of the plant was found to be in a range of 1.01%–2.64%. From the present study it is concluded that this plant could be used as a source of natural antioxidants and functional food nutraceutical application
New 14-Membered Cyclopeptide Alkaloids from Zizyphus oxyphylla Edgew
No full textTwo new 14-membered cyclopeptide alkaloids, Oxyphylline B (4) and Oxyphylline C (5), along with three known 13-membered cyclopeptide alkaloids, were isolated from stem and roots of Zizyphus oxyphylla Edgew. The compounds were tested for antibacterial activity. Oxyphylline B (4) showed comparatively better antibacterial activities against Escherichia coli (MIC, 5 μg/mL) than other compounds. This compound also exhibited weak antimicrobial activities against Staphylococcus aureus (MIC, 25 μg/mL), Pseudomonas aeruginosa (MIC, 50 μg/mL) and Salmonella typhi (MIC, 50 μg/mL)
Pharmacological Evaluation of Prosopis cineraria (L.) Druce in Gastrointestinal, Respiratory, and Vascular Disorders
Full text linkIn this paper, a crude methanolic extract from the stem bark of Prosopis cineraria, a plant native of Pakistan, was tested for its
possible presence of spasmolytic, bronchodilator, and vasodilator activities in an attempt to validate some of its folkloric uses.
Moreover, attempts weremade to provide plausible explanations of the observed biological activities. The extract caused relaxation
of the spontaneous as well as K+ (80mM)-induced contractions at tissue bath concentrations of 3–10 mg/mL in isolated rabbit
jejunumpreparations, probably mediated through blockade of Ca+2 channels. This finding was further confirmed by the shifting of the Ca+2 concentration response curves to the rightward in a manner similar to verapamil used as a standard Ca+2 channel blocker.
The extract also exhibited nonspecific relaxant effect on carbachol (1 μM)- and K+ (80 mM)-induced contractions in isolated rabbit tracheal preparations. The same effect was recorded for phenylephrine (11 μM) and K+ (80 mM)-induced contractions in isolated rabbit aortic preparations in a manner similar to verapamil. These observations confirmthat observed bronchodilator and vasodilator activities were possibly mediated through blockade of Ca+2 channels. The above-mentioned observations validate the traditional use of the plant in the treatment of respiratory and gastrointestinal ailments
Grewia asiatica L., a Food Plant with Multiple Uses
No full textGrewia asiatica L., is a species native to south Asia from Pakistan, east to Cambodia, cultivated primarily for its edible fruit and well-reputed for its diverse medicinal uses. Fruits are a rich source of nutrients such as proteins, amino acids, vitamins, and minerals and contain various bioactive compounds, like anthocyanins, tannins, phenolics and flavonoids. Different parts of this plant possess different pharmacological properties. Leaves have antimicrobial, anticancer, antiplatelet and antiemetic activities; fruit possess anticancer, antioxidant, radioprotective and antihyperglycemic properties; while stem bark possesses analgesic and anti-inflammatory activities. This review focuses on the botanical description, phytochemistry, nutritional studies and pharmacological properties of this plant
Zia-ul-Haq, Muhammad (1924-1988)
No full textIl contributo tratteggia sinteticamente la biografia politica di Muhammad Zia-ul-Haq, con particolare attenzione alle intersezioni fra dimensione religiosa e politica della sua azione
GOOGLEDORK, SEBUAH PENDEKATAN LANJUTAN PEMANFAATAN MESIN PENCARI SEBAGAI PENUNJANG LITERASI INFORMASI
No full textPemahaman yang cukup serta penguasaan teknik pencarian yang baik pada mesin pencari merupakan bagian dari keterampilan dalam berteknologi informasi. Penulis mengangkat pembahasan seputar GoogleDork yang merupakan teknik lanjutan (advanced) yang dapat diterapkan pada mesin pencari yang paling terkenal (Google Search) dan paling banyak digunakan saat ini. Pembahasan didahului dengan mendeskirpsikan beberapa teknik yang umum digunakan pada mesin pencari tersebut, selanjutnya dikomparasikan dengan teknik GoogleDork. Berdasarkan gambaran dan komparasi yang ada, disimpulkan bahwa teknik GoogleDork memiliki kekurangan dan kelebihan. Adapun kelebihannya terkait efektivitas, efesiensi dan ketepatan hasil. Dimana kelebihan-kelebihan tersebut merupakan aspek yang sangat menopang terwujudnya Literasi Informasi yang baik
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