120 research outputs found
sj-pdf-1-dos-10.1177_15593258221108280 – Supplemental Material for In-silico Studies Calculated a New Chitin Oligomer Binding Site Inside Vicilin: A Potent Antifungal and Insecticidal Agent
No full textSupplemental Material, sj-pdf-1-dos-10.1177_15593258221108280 for In-silico Studies Calculated a New Chitin Oligomer Binding Site Inside Vicilin: A Potent Antifungal and Insecticidal Agent by Ahsan Saeed, Zahra Rafiq, Muhammad Imran, Qamar Saeed, Muhammad Q. Saeed, Zahid Ali, Rana K. Iqbal, Saber Hussain, Binish Khaliq, Sohaib Mehmood and Ahmed Akrem in Dose-Response</p
Health monitoring in proactive reliability management of deteriorating concrete bridges
No full textEThOS - Electronic Theses Online ServiceGBUnited Kingdo
Doing Pre-operative Investigations in Emergency Department; a Clinical Audit
No full textIntroduction: Pre-operative investigations for emergency surgical patients differ between centers. Following established guidelines can reduce unnecessary investigation, cost of treatment and hospital stay. The present audit was carried out to evaluate the condition of doing pre-operative investigations for three common surgical emergencies compared to National Institute for Health and Care Excellence (NICE) guidelines and local criteria.Methods: A retrospective clinical audit of acute-appendicitis, abscess and hernia patients admitted to the emergency department was carried out over a one-year period from July 2014 to July 2015. Data of laboratory investigations, their indication, cost and duration of hospital stay was collected and compared with NICE-guidelines.Results: A total of 201 patients were admitted to the emergency department during the audit period. These included 77(38.3%) cases of acute-appendicitis, 112 (55.7%) cases of abscesses, and 12 (6%) cases of hernia. Investigations not indicated by NICE-guidelines included 42 (20.9%) full blood counts, 29 (14.4%) random blood sugars, 26 (12.9%) urea tests, 4 (2%) chest x-rays, 13 (6.5%) electrocardiographs, and 58 (28.9%) urine analyses. These cost 25,675 Rupees (245.46 Dollars) in unnecessary investigation costs and 65.7 days of additional hospital stay.Conclusions: Unnecessary investigations for emergency surgical patients can be reduced by following NICE-guidelines. This will reduce workload on emergency services, treatment costs and the length of hospital stay.</h2
Hickam's Dictum prevails: navigating the maze of dual pathology in HIV
No full textOPEN JOURNAL SYSTEMS
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ABOUT THE AUTHORS
Rafiq Shajahan
Medical Department, Hospital Kuala Lumpur
Imran Thoulath
Cardiology Department, Institut Jantung Negara
Malaysia
Rashida Safiuddin
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Ahmad Zuhri Shin Abd Halim
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Rozilah Ishak
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Suria Hayati Md Pauzi
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Nurismah Md Isa
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Wei Hao Kok
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Najma Kori
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Ummu Afeera Zainulabid
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
Petrick Periyasamy
Department of Internal Medicine, Faculty of Medicine, Hospital Canselor Tuanku Muhriz
Malaysia
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Home > 2023 > Shajahan
Hickam's Dictum Prevails: Navigating the Maze of Dual Pathology in HIV
Rafiq Shajahan, Imran Thoulath, Rashida Safiuddin, Ahmad Zuhri Shin Abd Halim, Rozilah Ishak, Suria Hayati Md Pauzi, Nurismah Md Isa, Wei Hao Kok, Najma Kori, Ummu Afeera Zainulabid, Petrick Periyasamy
Abstract
In the realm of HIV, considering various causes for clinical presentations is crucial. This case report reveals the exceptional coexistence of advanced neuroendocrine tumor and Burkitt's lymphoma, an infrequently reported combination in an individual with HIV. Emphasizing Hickam's Dictum, which promotes comprehensive exploration of multiple possibilities, rather than settling for a single diagnosis (Occam's razor), we present the intriguing journey of a 44- year-old man with HIV and hepatitis B co-infection. The patient, diagnosed with HIV and hepatitis B in 2017, discontinued antiretroviral therapy and presented to the emergency department with breathlessness. He experienced fever, night sweats, chronic diarrhoea, and a significant weight loss of 15 kg over six months. Physical examination revealed flushed cheeks, hepatomegaly, and other alarming signs. Initial treatment focused on disseminated tuberculosis, but further investigations unveiled heart failure and a pancreatic lesion. The clinical picture suggested neuroendocrine tumor and carcinoid syndrome, supported by elevated serum chromogranin levels. A colonoscopy ruled out gastrointestinal involvement but surprisingly revealed Burkitt's lymphoma. Tragically, the patient succumbed to a carcinoid crisis. This case highlights the importance of considering multiple differentials in HIV-infected individuals, as illustrated by the convergence of neuroendocrine tumor and Burkitt's lymphoma. Previous case reports suggest an unusual link between carcinoid tumours and lymphoreticular malignancies. Neuroendocrine hormones may influence the proliferation and mitogenesis of lymphoid cells that may develop into diseases. Vigilance in recognizing and understanding dual pathology can aid in reducing mortality. Further research is needed to explore potential connections between these rare malignancies
Crowd Modeling using Temporal Association Rules
No full textUnderstanding crowd behavior has attracted tremendous attention from researchers over the years. In this work, we propose an unsupervised approach for crowd scene modeling and anomaly detection using association rules mining. Using object tracklets, we identify events occurring in the scene, demonstrated by the paths or routes objects take while traversing the scene. Allen\u27s interval-based temporal logic is used to extract frequent temporal patterns from the scene. Temporal association rules are generated from these frequent temporal patterns. Our goal is to understand the scene grammar, which is encoded in both the spatial and spatio-temporal patterns. We perform anomaly detection and test the method on a well-known public data
Reduction of Greenhouse Gas Emissions from Gas, Oil, and Coal Power Plants in Pakistan by Carbon Capture and Storage (CCS): A Review
No full textEffects of Organizational Factors on Knowledge Sharing: A Systematic Review of Empirical Studies
No full textIn organizations, knowledge sharing is a major source of innovation, performance, success, and goal achievement. This review-based study aims to extract the determinants of knowledge sharing from previously conducted studies. It also explores the organizational factors that have been most emphasized in studies on knowledge sharing. Following inclusion and exclusion criteria, fifty-four studies were selected for review and analysis to achieve the study objectives. Organizational culture, organizational support, organizational commitment, and organizational rewards are identified as highly important factors, while relationships, organizational justice, organizational trust, organizational leadership, and organizational climate are found to be very important factors. Additionally, some organizational factors are identified as quite important, somewhat important, and less important or ignored factors in the realm of knowledge sharing. Iran emerges as a productive country for producing research on knowledge sharing, with staff members/employees being a prolific population, and academia being a prolific discipline/site. This study will provide guidance to researchers on lesser-explored or ignored organizational variables to consider in their research on knowledge sharing
Standard of surgical venous thrombo-prophylaxis in admitted patients
No full textObjective: To determine the standard of venous-thrombosis prophylaxis at the Surgical Department of Khyber Teaching Hospital, Peshawar.
Methods: A retrospective clinical audit of patients admitted to the surgical department over a one-year period from July 2014 to July 2015 was carried out. Data on risk assessment for venous thrombosis and prophylaxis was collected, including indications for enoxaparin and graduated stockings, their prescription and use. The correct dose and timing for enoxaparin, review of prophylaxis and counselling was also noted.
Results: 157 patients, including 37 (23.6%) males and 120 (76.4%) females requiring thromboembolism prophylaxis were admitted to the emergency department during the audit period. Mean age was 50.97±12.74 years. Enoxaparin was indicated in all 157 patients, prescribed to 126 (80.3%) and administered in 120 (76.4%), respectively. Only 80 (51%) patients received the correct dosage and 85 (54.1%) patients received it at the required time. Graduated stockings were indicated in 110 (70.1%) patients, prescribed in 35(22.3%) cases and applied in 28 (17.8%), respectively. Review of prophylaxis was not performed in any of the patients at 72 hours. Counselling and information was provided to 31 (19.7%) patients. Thrombotic events occurred in 17 (10.8%) cases, of which 12 (7.6%) were lower limb deep venous thromboses and 5 (3.2%) were cases of pulmonary embolism.
Conclusions: The audit fell short of the guidelines. Enoxaparin was prescribed and administered only in certain cases, both with the wrong timing and dosage. Stockings administration was rare and its counselling was lacking. Review of management was not performed in any case. The proposed recommendations should be implemented and assessed afterwards with a second audit cycle. [Arch Clin Exp Surg 2017; 6(2.000): 74-80
Enhancing Intelligence in Multi-Agent Systems with Edge-Assisted Causal Knowledge Aggregation
No full textData availability:
The datasets generated and analyzed during the current study, including occupancy grid maps, robot trajectories, and simulation results, are available from the corresponding author upon reasonable request. Due to hardware-specific constraints, real-world UGV and TurtleBot4 data can be shared in processed form to ensure reproducibility.Dynamic and uncertain environments pose major challenges for multi-agent autonomous systems, particularly in achieving robust simultaneous localization and mapping (SLAM) and efficient knowledge sharing across robots. Conventional data-driven methods often overlook underlying causal structures, resulting in spurious correlations and limited generalization. To address this, we present CASK—an edge-assisted causal knowledge aggregation framework that fuses structured causal inference with data-driven learning to improve adaptive decision-making. A key feature is a time-based normalization mechanism that ensures mapping consistency across varying operational speeds, enabling speed-independent transfer of spatial knowledge between heterogeneous agents. We validate CASK through simulations and real-world experiments using autonomous ground vehicles, a class of mobile robots. Results show substantial gains over state-of-the-art methods: up to 20% higher success at low speeds, 40% at high speeds, 50% lower trajectory deviation, and 45% fewer re-planning steps. These findings demonstrate how causal inference combined with mobile edge computing enables scalable, reliable, and generalizable autonomy in multi-agent systems.The authors acknowledge support from the University of Glasgow and the Scotland 5G Centre. We also thank colleagues at the James Watt School of Engineering for their technical guidance and provision of laboratory facilities. This work was supported in part by EPSRC Projects, CHEDDAR under Grant EP/X040518/1 and in part by CHEDDAR uplift under Grant EP/Y037421/1
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