3,005 research outputs found
Microcredit, the corporatization of nongovernmental organizations, and academic activism: The example of Professor Anu Muhammad
No full textBased on an interview with academic-activist Professor Anu Muhammad, this edited transcript illuminates the corporatization of nongovernmental organizations, with specific reference to perpetuating the negative effects of neoliberal microcredit practices in developing countries. It focuses upon how such corporatization is contributing to corruption and the weakened role of the state. The concept of poor-people-led cooperatives is proposed as an alternative as they are more congruent with actively maintaining cultural traditions, protecting social cohesion, and mobilizing collective community-level energy to alleviate misery and reduce poverty
CHOLECYSTOKININ STIMULATES DOPAMINE SYNTHESIS IN SYNAPTOSOMES BY A CYCLIC AMP-DEPENDENT MECHANISM
No full textThe effects of different fragments of cholecystokinin (CCK) on dopamine synthesis were studied in synaptosomal preparations from the striatum, substantia nigra, and frontal cortex. In striatal synaptosomes, dopamine synthesis rate measured by dopamine accumulation was 12.5% lower than that measured by 3,4-dihydroxyphenylalanine (DOPA) accumulation; however, K+-accelerated synthesis was the same for both methods. Synthesis rate was independent of exogenous tyrosine levels. In the three regions studied, the combined stimulatory effects of 8-Br-cyclic AMP and high K+ were additive. CCK-5, CCK-3, CCK-27-33, and CCK-8 (sulphated) enhanced synthesis, CCK-5 being the most potent fragment. The nonsulphated octapeptide had no effect. In all three regions, CCK-5 and high K+ had an additive effect on dopamine synthesis; CCK-5 and 8-Br-cyclic AMP together produced the same enhancement of synthesis as CCK-5 alone. CCK-5 produced similar dose-dependent increases in dopamine synthesis and cyclic AMP accumulation in striatal synaptosomes, and both effects were blocked by the CCK antagonist proglumide
sj-pdf-1-whe-10.1177_17455057231199032 – Supplemental material for Knowledge, attitudes, and practices of female health care service providers on female genital mutilation in Somalia: A cross-sectional study
No full textSupplemental material, sj-pdf-1-whe-10.1177_17455057231199032 for Knowledge, attitudes, and practices of female health care service providers on female genital mutilation in Somalia: A cross-sectional study by Nadira Mehriban, Abu Naser Zafar Ullah, Md Imdadul Haque, Md Golam Dostogir Harun, Deka Mohamed Isse, Faisal Muhammad, ABM Alauddin Chowdhury, Moniruddin Chowdhury, Md Zobaer Hasan and Thomas Dessoffy in Women’s Health</p
Dopamine restores reward prediction errors in old age
No full textSenescence affects the ability to utilize information about the likelihood of rewards for optimal decision-making. Using functional magnetic resonance imaging in humans, we found that healthy older adults had an abnormal signature of expected value, resulting in an incomplete reward prediction error (RPE) signal in the nucleus accumbens, a brain region that receives rich input projections from substantia nigra/ventral tegmental area (SN/VTA) dopaminergic neurons. Structural connectivity between SN/VTA and striatum, measured by diffusion tensor imaging, was tightly coupled to inter-individual differences in the expression of this expected reward value signal. The dopamine precursor levodopa (L-DOPA) increased the task-based learning rate and task performance in some older adults to the level of young adults. This drug effect was linked to restoration of a canonical neural RPE. Our results identify a neurochemical signature underlying abnormal reward processing in older adults and indicate that this can be modulated by L-DOPA
Dynamical mean-field theory of realistic spin glasses beyond independent-mode approximation. II. Effect of reaction field
No full textThe author extends the previous calculation on a dynamical mean-field theory of realistic spin glasses (Chowdhury and Mookerjee) so as to incorporate the effect of the reaction field. The 'ordering temperature' of a mode is shown to depend not only on the corresponding eigenvalue of the random matrix J but also on the structure of the whole spectrum
Supplementary_Figure_S2 – Supplemental material for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer
No full textSupplemental material, Supplementary_Figure_S2 for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer by Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat and Syed S. Islam in Therapeutic Advances in Medical Oncology</p
Supplementary_Figure_S3 – Supplemental material for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer
No full textSupplemental material, Supplementary_Figure_S3 for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer by Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat and Syed S. Islam in Therapeutic Advances in Medical Oncology</p
Supplementary_Table_S2 – Supplemental material for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer
No full textSupplemental material, Supplementary_Table_S2 for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer by Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat and Syed S. Islam in Therapeutic Advances in Medical Oncology</p
Supplementary_Figure_S5 – Supplemental material for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer
No full textSupplemental material, Supplementary_Figure_S5 for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer by Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat and Syed S. Islam in Therapeutic Advances in Medical Oncology</p
Supplementary_Figure_S4 – Supplemental material for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer
No full textSupplemental material, Supplementary_Figure_S4 for Widespread expression of Sonic hedgehog (Shh) and Nrf2 in patients treated with cisplatin predicts outcome in resected tumors and are potential therapeutic targets for HPV-negative head and neck cancer by Abu Shadat M. Noman, Rashed R. Parag, Muhammad I. Rashid, Mohammad Z. Rahman, Ali A. Chowdhury, Afrin Sultana, Chandsultana Jerin, Ayesha Siddiqua, Lutfur Rahman, Afsana Shirin, Junayed Nayeem, Reaz Mahmud, Sonam Akther, Rajib K. Shil, Ikram Hossain, Sharmin Alam, Arfina Chowdhury, Shabnam B. Basher, Abul Hasan, Shammy Bithy, Jannatul Aklima, Mizanur Rahman, Nabila Chowdhury, Tahmina Banu, Bedri Karakas, Herman Yeger, Walid A. Farhat and Syed S. Islam in Therapeutic Advances in Medical Oncology</p
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