118,887 research outputs found

    NEUROPEPTIDES ANALYSIS OF OCTOPUS VULGARIS TRANSCRIPTOME: OCT-PEDAL PEPTIDE EXPRESSION IN CNS LOBES INVOLVED IN MOTOR COORDINATION

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    The discovery of novel peptides and hormones from the phylum Mollusca, enabled by the availability of whole genomes, transcriptomes and peptidomes, gives now ample tools for studying the structural evolution of peptides and hormones, and for redefining the phylogenetic relationships of key families of peptide and hormones across ecdysozoans, lophotrochozoans and chordates. In this frame, the genome sequence of the limpet Lottia gigantea (Veenstra, 2010) and the initiated large-scale molluscan transcriptome and genome projects (Moroz et al., 2011; De Lisa et al., 2011; Di Cosmo and Polese, 2012) offer an excellent opportunity to look at the neuropetides and neurohormone genes. Mollusks have several genes coding pedal peptides (PP), three in Lottia and four in Aplysia (Veenstra, 2010). Neuropeptides are the fastest evolving intercellular signals; in particular, cephalopods developed a number of specific innovations in their repertoire of secretory molecules that might supp ort their unique features (Moroz, 2011). Using neuronal transcriptome from Octopus vulgaris, we developed a specific probe to analyze expression of Oct-PP in O. vulgaris brain in horizontal sections throughout the suboesophageal and supraoesophageal masses, including optic lobes. Performing ISH analysis we found the expression of Oct-PP mRNA confined in the anterior suboesophageal mass, in the prebrachial lobe and in the middle suboesophageal mass, in all pedal lobes. The prebrachial lobe is involved in reflex coordination. The middle suboesophageal mass, representative of the pedal ganglionated cord of early mollusks, is involved in all actions in Octopus (Young, 1971). Our findings support the involvement of Oct-PP in reflex and motor coordination in Octopus

    Square Dancing with the Stars to Enhance Dynamic Hirschman Linkages?

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    In this Presidential Address, the author takes the reader on a reconnaissance of his life and time as a regional scientist. He points out scenery he found scintillating along the way, hoping that some may pick up the banner and chew on a few of the ideas for a while. He suggests a revisit to Albert O. Hirschman’s notion of key sectors and more empirical analysis related to Marcus Berliant’s and Masahisa Fujita’s notion of knowledge creation and transfer.Presidential Address, San Antonio, Texas, March 29, 2014 (53rd Meetings of the Southern Regional Science Association

    Letter from unknown writer to Jesse L. Boyce

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    Letter to Jesse L. Boyce from unknown author (possibly Jack) about the investigation into the powder magazine located in the Grand Canyon. Some personal news is included in the letter such as the writer's marriage to the daughter of C.A. Taylor, former Supervisor of Cochise County

    Letter from Carl Hayden to L. L. Ferrall, Postmaster at Grand Canyon

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    Letter from Carl Hayden to L. L. Ferrall on the favorable conditions for creating a national park and the prospect of the United States entering WW I

    Sarah L. Blum Author Visit - Warrior Nurse: PTSD and Healing

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    Hear Sarah L. Blum, author of Women Under Fire: Abuse in the Military, discuss her newest book, Warrior Nurse: PTSD and Healing followed by a Q&A and book signing. Sarah L. Blum is a decorated Vietnam veteran who served as an operating room nurse during the intense fighting of 1967. In recognition of her service, she was awarded the Army Commendation Medal. Sponsored by CWU Veterans Center and CWU Libraries.https://digitalcommons.cwu.edu/libraryevents/1252/thumbnail.jp

    Introducing the Recent development in input-output analysis

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    This is a draft chapter. The final version is available in Recent Development in Input-Output Analysis, edited by Erik Dietzenbacher, Michael L. Lahr, and Manfred Lenzen, published in 2020, Edward Elgar Publishing Ltd. https://doi.org/10.4337/9781786430816. The material cannot be used for any other purpose without further permission of the publisher, and is for private use only

    Letter from L. L. Ferrall, Postmaster at Grand Canyon to Carl Hayden

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    Letter from Grand Canyon Postmaster L. L. Ferrall to Carl Hayden regarding the proposed national park bill. Ferrall states that nearly all those who live in the canyon are against it as it gives a monopoly to the railway and hopes that the bill does not start "a war" for Arizona

    [Index tab labeled "L" #1]

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    Index tab labeled "L", by an unknown author
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