323,047 research outputs found

    Sani S., La politica scolastica del Centro-Sinistra (1962-1968), Morlacchi Editore, Perugia 2000

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    Recensione al volume: Sani S., La politica scolastica del Centro-Sinistra (1962-1968), Morlacchi Editore, Perugia 200

    Flux tubes and string breaking in three dimensional SU(2) Yang-Mills theory

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    We consider the three dimensional SU(2) Yang-Mills theory with adjoint static color sources, studying by lattice simulations how the shape of the flux tube changes when increasing the distance between them. The disappearance of the flux tube at string breaking is quite abrupt, but precursors of this phenomenon are present already when the separation between the sources is smaller than its critical value, a fact that influences also some details of the static potential

    Modeling Stented Coronary Arteries: Where We are, Where to Go

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    In the last two decades, numerical models have become well-recognized and widely adopted tools to investigate stenting procedures. Due to limited computational resources and modeling capabilities, early numerical studies only involved simplified cases and idealized stented arteries. Nowadays, increased computational power allows for numerical models to meet clinical needs and include more complex cases such as the implantation of multiple stents in bifurcations or curved vessels. Interesting progresses have been made in the numerical modeling of stenting procedures both from a structural and a fluid dynamics points of view. Moreover, in the drug eluting stents era, new insights on drug elution capabilities are becoming essential in the stent development. Lastly, image-based methods able to reconstruct realistic geometries from medical images have been proposed in the recent literature aiming to better describe the peculiar anatomical features of coronary vessels and increase the accuracy of the numerical models. In this light, this review provides a comprehensive analysis of the current state-of-the-art in this research area, discussing the main methodological advances and remarkable results drawn from a number of significant studies

    ROMA: Il PIANO DELLA TUTELA DELL’IMMAGINE DELL’AREA Urbana del II Municipio (Colore e Arredo Urbano)

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    DVD presentato in occasione del Convegno svoltosi a Roma presso il Complesso di S. Michele a Ripa

    The Unreasonable effectiveness of effective string theory: The case of the 3D SU(2) Higgs model

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    We study string breaking in the three-dimensional SU(2) Higgs model, using values of the gauge coupling for which the confinementlike and Higgs-like regions of the phase diagram are separated just by a smooth crossover. We show that even in the presence of string breaking, the confining part of the interquark potential is well described by the effective string theory and that also the fine details of the effective string, like the higher order terms of the Nambu-Goto action or the boundary correction, can be precisely extracted from the fits and agree with the effective string predictions. We comment on the implications of these results for QCD simulations with dynamical quarks

    Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion

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    Multiple mechanisms operate to ensure T-cell tolerance toward self-antigens. Three main processes have been described: clonal deletion, anergy, and deviation to CD4 + regulatory T cells (Tregs) that suppress autoreactive T cells that have escaped the first 2 mechanisms. Although it is accepted that dendritic cells (DCs) and B cells contribute in maintaining T-cell tolerance to self-antigens, their relative contribution and the processes involved under physiologic conditions remain only partially characterized. In this study, we used different transgenic mouse models to obtain chimeras where a neo self-antigen is expressed by thymic epithelium and/or by DCs or B cells. We found that expression of cognate ligand in the thymus enhances antigen-specific FoxP3 + cells independently of whether the self-antigen is expressed on thymic epithelium or only on DCs, but not on B cells. On the contrary, self-antigen expression by B cells was very efficient in inducing FoxP3 + cells in the periphery, whereas self-antigen expression by DC led mainly to deletion and anergy of antigen-specific FoxP3 - cells. The results presented in this study underline the role of B cells in Treg induction and may have important implications in clinical protocols aimed at the peripheral expansion of Tregs in patients
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