1,721,069 research outputs found
Cyclosporin A upregolates phospholipase-C b1 nuclear expression in fibroblasts from hearth–transplanted patients with gingival overgrowth
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Medical emergencies in the dental office
No full textOBJECTIVES. To review the factors that can provoke medical emergencies in patients undergoing dental procedures and to identify appropriate measures for managing patients at risk for such events before, during, and after treatment. MATERIALS AND METHODS. Dentists are frequently faced with patients suffering from systemic diseases that can be associated with medical emergencies. The risk of such events is also conditioned by factors related to dental procedures themselves, including local anesthesia, stress, and pain. This article examines measures designed to reduce this risk, the importance of a complete history in identifying true high-risk patients, and methods that can be used to control pain and anxiety, with emphasis on the most appropriate types of local anesthesia for various procedures. RESULTS AND CONCLUSIONS. Protocols are provided for the management of medical emergencies, with emphasis on the maneuvers and drugs that can be used in dentist's office and on the importance of early requests for hospitalization in emergency situations characterized by high risk
“Trattamento con laserterapia delle lesioni precancerose del cavo orale: esperienza dell’Azienda Ospedaliera S.Orsola di Bologna”
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A prospective clinical trial for assessing the efficacy of a minimally invasive protocol in patients with bisphosphonate-associated osteonecrosis of the jaws
No full textObjective: The objective of this study was to assess whether a minimally invasive protocol can be effective in the long-term control of necrotic areas and pain in patients suffering osteonecrosis of the jaw associated with the use of bisphosphonate drugs (BRONJ). Study design: Thirty-four consecutive patients (14 male, 20 female) with BRONJ under treatment with zoledronate, pamidronate, or alendronate were enrolled. All of the patients received professional oral hygiene treatment and antiseptic oral rinses, and if in pain they assumed an antibiotic therapy with amoxicillin/clavulanate potassium and metronidazole for ten days. At the baseline visit, as well as at each 3-month recall, the size of the osteonecrotic lesions were measured and the pain level assessed with a visual analog scale. Results: The results from the general linear model showed a statistically significant (F = 16.1; P <.01; r 2 = 0.95) time-related decrease in the size of exposed bone areas during the nonsurgical therapy (from 12.5 ± 12.0 mm to 8.8 ± 10.3 mm). Conclusions: This conservative protocol seems to provide successful treatment in the vast majority of patients. © 2011 Mosby, Inc. All rights reserved
A multilevel analysis of platform-switching flapless implants placed at tissue level: 4-year prospective cohort study
Full text linkPurpose: To evaluate the factors affecting peri-implant marginal bone level of single platform-switched implants with a smooth neck placed at gingival level (tissue level) using a flapless technique. Materials and Methods: Consecutive healthy patients requiring dental implant rehabilitations were enrolled in this study. Titanium implants with a zirconium-oxide-blasted surface and a platform-switch neck tulip configuration were used. Loading was performed 3 months after insertion with a provisional resin crown and after approximately 15 days with a definitive ceramic crown. Peri-implant marginal bone level (MBL) was measured on periapical radiographs at 1, 3, 6, 12, 24, 36, and 48 months by a blinded assessor. The following parameters were evaluated: location (maxillary/mandibular), position (anterior/posterior), sex (male/female), smoke (yes/no), implant placement timing (immediate, early, delayed), gingival thickness (thin/thick), endodontically treated adjacent teeth (yes/no), and diameter (3.8/4.25/5.0 mm). Multilevel analyses exploring factors associated with MBL at 36 and 48 months were performed. Results: A total of 76 patients (42 women, 34 men; mean age: 55.6 ± 10.7 years) received 128 implant rehabilitations. The survival rate was 98.4%. MBL displayed an initial increase during the first months from insertion (preload period). Cumulative mean MBL at T48 was 0.99 ± 0.68, which was not statistically significant from the values at T24 to T36 (P >.05). Mandibular location, delayed implants, and presence of adjacent endodontically treated teeth showed higher bone loss at 36 months (P <.05). Interestingly, at 48 months, only implant placement timing showed statistically significant differences. Delayed implants showed increased bone loss compared with both early and immediate groups (P <.05). Multilevel analysis confirmed the statistical significance of implant location (P =.031; 95% CI: 0.031 to 0.659), endodontically treated adjacent teeth (P =.001; 95% CI:-1.228 to 0.859), and implant placement (P =.045; 95% CI: 0.003 to 0.337) as factors affecting MBL at 36 months. All the investigated parameters, with the only exception being the implant placement group (P =.020; 95% CI: 0.334 to 1.432), were not statistically significant at 48 months (P >.05). Conclusion: Platform-switched implants placed nonsubmerged with a flapless approach showed a reduced bone loss progression in the first 4 years, as MBL remained stable at longer times (36 and 48 months). Implants placed with early and immediate timing showed reduced bone loss compared with delayed implants
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
The perceived impact of the COVID-19 pandemic on dental undergraduate students in the Italian region of Emilia-Romagna
No full textIntroduction: The outbreak and diffusion of the novel SARS-CoV2 coronavirus have caused an emergency status in the dental education system. Materials and methods: An anonymous survey composed of 34 questions was delivered to students of the Master Degree Programme in Dentistry and Dental Prosthodontics of the Universities of Emilia-Romagna, the fifth Italian region most affected by the pandemic. The psychological impact of COVID-19 was assessed by means of the Generalised Anxiety Disorder-7 scale (GAD-7). Numerically recoded data were analysed using the Analysis of Variance (ANOVA), whilst to investigate the association between quantitative variables, the Pearson correlation coefficient (R) was computed. Results: The questionnaire was completed by 399 students (75%) out of 532. Most students experienced difficulties in working at the thesis during the COVID-19 emergency. For over half of them, online teaching could only partially replace traditional face-to-face lessons. The negative impact on the study career was judged as particularly high by sixth-year students. Clinical training activities were considered as exposing to the risk of contracting COVID-19 infection by the majority of the students. The level of concern of contracting COVID-19 infections during future university activities was positively correlated to risk perception related to clinical training. Conclusion: The results of this survey could be used to train students to a correct risk assessment. Students reported experiencing concern whilst thinking of COVID-19 and 6.5% of them showed symptoms related to high levels of anxiety. These data may guide Universities in trying to reduce students' anxiety by means of correct communication strategies
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