78 research outputs found

    Biological and phytochemical studies of five Malaysian Uncaria species / Hashimah Mohd Hashim

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    In this study, five species of Uncaria (family Rubiaceae) also known as “Gambir” widely used as traditional medicine in Malaysia were evaluated for their biological activities as well as phytochemical and total phenolic contents. They are U. calophylla, U. acida, U. lucida, U. cordata and U. longiflora var pteropoda. The methanolic extracts of the plants are subjected to various bioassays including antioxidant, radical scavenging (by 1,1-diphenyl-2-picrylhydrazyl or DPPH) method, antimicrobial (by hole-plate diffusion method) and antihyperglycemic assay (in-vitro inhibition of α-glucosidase enzyme and in-vivo assay). The total phenolic content (TPC) of the plants was evaluated by the Folin-Ciocalteau method. All tested extracts exhibited very strong antioxidant potential (>85% inhibition) in the FTC and TBA assays. In the DPPH assay, U. longiflora (stems and leaves) showed strong radical-scavenging properties with IC50 values of 8-10 µg/ml comparable to vitamin C. In the antimicrobial assay, most extracts displayed good antimicrobial activity against Gram-positive bacteria. U. longiflora was found to inhibit Candida albicans with MIC value of <1.0 µg/ml for both leaves and stems comparable to cyclohexamide. In the in-vitro and in-vivo assays, U. longiflora (stems), U. acida (leaves) and U. cordata (stems) showed very good antihyperglycemic potential. On the basis of chemical and biological screening, U. longiflora (stems) was selected for phytochemical investigation. Repeated chromatographic techniques on the bioactive fraction resulted in the isolation of two major compounds ULs1 and ULs2 identified as pentacyclic alkaloids isomitraphylline and isopteropodine based on 1H and 13C NMR spectroscopic data. ULs1 exhibited stronger antioxidant and α-glucosidase activities than ULs2 which could relate to better immuno-modulatory properties of isomitraphylline. In the αglucosidase inhibitory assay, these two compounds also showed dose-dependent activities indicating their potential as antihyperglycemic agents for type II diabetes

    Transkrip temubual bersama Puan Amy Hashmida binti Hashim pelukis wanita muslim pertama / Nurul Izzati Mohd Zaki and Siti Sarah Kauli

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    Amy Hashmida Binti Hashim merupakan anak kelahiran Negeri Che Siti Wan kembang. Berusia 50 tahun, salah satu lukisan beliau yang bertajuk ‘paddy field – After Harvest’ Berjaya tersenarai dalam Top 100 dalam sebuah pertandingan lukisan di Palo Alto, California. Tujuan temubual ini di jalankan bertujuan untuk membuat kajian tentang pelukis wanita muslimah pertama ke luar Negara dan juga untuk mendapat maklumat lisan yang boleh dijadikan rujukan untuk masa akan datang dan untuk mengetahui rahsia disebalik kejayaan seorang pelukis. Menceritakan tentang kejayaan dan anugerah diperoleh oleh Puan Amy Hashimah Binti Hashim Sepanjang beliau bergiat aktif dalam bidang seni. Kaedah kajian ini dijalankan dengan secara temuramah dan mengumpul data. Penyelidikan ini dilakukan dengan mengadakan temu ramah bersamah tokoh wanita Kelantan iaitu Puan Amy Hashimah melalui Zoom, sebanyak 100 soalan yang dikemukakan yang terdiri daropada latar belakang, sejarah pendidikan sekolah, kerjaya tokoh, pencapaian sumbangan dan harapan tokoh

    Copper, lead and diphenylamine in gunshot residue analysis using screen printed carbon electrode (spce) and gold coated spce / Nurul 'Afiqah Hashimah Mohd Hashim

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    Electrochemical analysis on screen printed carbon electrode (SPCE) is relatively simple, rapid and reliable tool inorganic compound identification such as copper in gunshot residue (GSR). SPCE is specially designed to cope with microvolumes of sample such as GSR sample due to its potential for miniaturization and facility of automation. It would be beneficial for the quantification of copper in GSR for a forensic analyst in the fastest way at the discharging area. The coating of gold on SPCE enhances the voltammetric performances towards detection of copper, lead and diphenylamine. The coupling of voltammetry with gold coated SPCEs allows the onsite preliminary test and improves the conventional method which capable to analyze GSR in the laboratory in the long period and have a risk of sample loss. The gold coated SPCE was swabbed directly on the shooter's arm immediately after discharging a firearm and the sample SPCE was analyzed using cyclic voltammetric method. The electrochemical performances of copper, lead and diphenylamine on bare SPCE and gold coated SPCE using voltammetric method were studied. Gold coated SPCE was characterized and optimized before field work. The voltammetric sensor responded to a series of 1 ppm to 100 ppm of copper solution shows gold coated SPCE increased the percentage of reproducibility about 5 % to 17 % in aspect of current density compared to bare SPCE due to their large effective surface area, effective catalysis and fast mass transport. GSR analysis was performed on Glock, Rifle Stryer AUG-Al and Rifle Colt M16-A1 using cyclic voltammetry and Inductive Coupled Plasma-Optical Emission Spectroscopy (ICP-OES) methods. The results obtained from cyclic voltammetric analysis show sopper concentrations detected in Glock, Rifle Stryer AUG-Al and Rifle Colt M16-A1 were 0.680 ppm, 1.349 ppm and 0.707 ppm respectively while the amounts of copper detected by ICP-OES analysis were 0.724 ppm (Glock), 1.432 ppm (Rifle Stryer AUG-Al) and 0.748 ppm (Rifle Colt M16-A1). The paired Student's t-test indicated that there was no significant difference between the results obtained from both methods at the 94 % confidence level. A p-va\ue of less than 0.05 was considered significant. Therefore, it can be concluded that the proposed method is reliable and can be successfully applied to the copper determination in GSR analysis

    Pendidikan Remaja Dalam Pusat Pemulihan Mencari Yang Ditinggalkan.

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    Kunci utama dalam membina sumber manusia yang berkualiti dan lestari adalah melalui sebuah sistem pendidikan yang baik. Sebuah sistem pendidikan yang baik mestilah memiliki ciri-ciri seperti inklusif dan kualiti pendidikan yang saksama serta mempromosikan pembelajaran yang melangkaui kumpulan umur sasaran biasa dan menjangkaui ruang serta kerangka masa yang ditetapkan (Sustainable Development Goal 4). Berdasarkan piawaian tersebut, kita percaya bahawa sistem pendidikan pemulihan seperti pusat pemulihan tidak seharusnya dipisahkan dan ditinggalkan dalam memikirkan tentang pendidikan yang mampan. Kajian ini merupakan satu usaha penerokaan awal bagi memahami pengalaman serta cabaran yang dihadapi dari perspektif pesalah juvana Malaysia dalam meneruskan pendidikan sewaktu menjalani hukuman tahanan di pusat pemulihan

    Stress, coping and social supports in adolescent years

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    This paper results from a study that was conducted on 209 Form Four students from two schools in Penang. In this study, a semi-structured interview covering questions on demographics, a 12-item measure of self-esteem, and a 20-item measure of well-being was conducted. Students were also asked to report their Penilaian Menengah Rendah (PMR) results as an indicator of their academic performance. To assess stress, coping and social supports, respondents were given a list of possible stressors (e.g., problems with relationships at home and school) and were asked to indicate whether or not they were bothered by these stressors, the type of coping that they had used in dealing with these stressors, and the type of social supports that they had received in relation to these stressors. A higher proportion of respondents (77%) identified issues related to academics and lessons as a problem compared to other issues (relationships at home, 34%, and relationships at school, 31%). The number of stressors related to everyday life was significantly related to well-being, but not to self-esteem or academic performance. Respondents reported a variety of problem-specific coping. Supports received were also problem-specific in nature. The findings have both applied and theoretical implications

    Character Strengths and Positive Outcomes

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    Character strengths have been defined as positive traits associated with individual differences. It has been explored as part of the personality that contributes to well-being, happiness and flourishing. This paper provides a review of the VIA Classification of character strengths and the relationships between character strengths and positive outcomes. Previous research shows that different character strengths predict different outcomes. From the review, character strengths have been found to generally increase life satisfaction, flourishing and leadership. Character strengths also have significant relationships with coping with stress, mastering online education system and recovering from addiction behaviour. Most of the studies were conducted in Western countries across a variety of population. The review highlights the importance of studying character strengths, especially in less studied samples such as Malaysia

    Exploring Women’s Relationships: An analysis of Malaysian Women’s Lifestyle Magazines

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    This study presented content analysis of two women’s lifestyle magazines for the period of January until June 2016. Combining media studies and relationship research, this paper examined cover pages and cover stories of two highly popular and widely circulated women’s lifestyle magazines in Malaysia; Nona and Wanita. Preliminary analysis indicated women who appeared in the cover page and cover story of the two magazines were attractive, successful and that they held prominent positions within society. They included businesswomen, actresses and politicians/activists. Women’s relationships, as portrayed in these magazines, comprised of children, husbands and family and this is consistent with their private roles as mothers, wives, sisters and daughters. From the analysis, women in the cover pages of these two magazines continued to be presented in traditional and patriarchal gender roles including being nurturant and submissive with an emphasis on their sexuality. This is in spite of them holding non-traditional roles as providers and representing success stories of women in public domain. The analysis provided supports that gender roles and cultural expectations continue to influence people’s social experiences. In addition, these gender roles cultural expectations also shape and at the same time enhanced by the representations in the media

    STRESS, COPING AND SOCIAL SUPPORTS IN THE ADOLESCENT YEARS

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    This paper results from a study that was conducted on 209 Form Fourstudents from two schools in Penang. In this study, a semi-structuredinterview covering questions on demographics, a 12-item measure ofself-esteem, and a 20-item measure of well-being was conducted.Students were also asked to report their Penilaian Menengah Rendah(PMR) results as an indicator of their academic performance. To assess stress, coping and social supports, respondents were given a list of possible stressors (e.g., problems with relationships at home and school) and were asked to indicate whether or not they were bothered by these stressors, the type of coping that they had used in dealing with these stressors, and the type of social supports that they had received in relation to these stressors. A higher proportion of respondents (77%) identified issues related to academics and lessons as a problem compared to other issues (relationships at home, 34%, and relationships at school, 31%). The number of stressors related to everyday life was significantly related to well-being, but not to self-esteem or academic performance. Respondents reported a variety of problem-specificcoping. Supports received were also problem-specific in nature. Thefindings have both applied and theoretical implications

    Advancing Positive Psychology in South East Asia: the Importance of Culture

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    Interest in the field of positive psychology has been overwhelming. This can be observed from the number of academic conferences and journals attributed to this field. Similar patterns can be observed in Asia where more and more research are concentrating on investigating constructs deemed as important within the field of positive psychology. However, comparable to other fields within psychology, positive psychology cannot ignore the importance of culture. This is especially true in South East Asian context when culture is arguably distinct from the American/European traditions in which positive psychology was originated from. Culture is likely to play a significant role in determining how human strengths are being conceptualized and nurtured and eventually determined a persons well-being and success as experienced within that particular society. Based on some findings from a research of adolescents happiness and well-being in Malaysia, this paper highlights the importance of culture in advancing positive psychology in Asia. More specifically, findings from this research demonstrated the importance of positive psychology in understanding and improving quality of life for certain groups of people in a particular society and illustrated several significant cultural and subcultural differences that can potentially enrich our understanding of positive psychological constructs. Findings also indicated the importance of culturally embedded constructs such as family relations and spiritual elements in contributing to happiness. Finally findings from this study suggested the need to unpack more general constructs such as positive relationships and meanings of life as they are contextualized within a specific culture and the call for further exploration on other constructs related to human positive attributes and strengths.Keyword: positive psychology, wellbeing, culture, an

    Hubungan Interpersonal Golongan ‘Pengkid’ di Malaysia

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    This research focuses on Pengkid. Pengkid is a term or a slang used in Malaysia to refer to lesbians in the butch category. They are a group of individuals who practices same sex sexual orientation, in which they are sexually attracted to women. This research was conducted to examine interpersonal relationships of Pengkid and their satisfaction over these relationships. To gain a deeper and more comprehensive picture, a semi-structural interview was conducted with 25 Pengkid participants from around Pulau Pinang, Kuala Lumpur, and Selangor. Participants were recruited using various methods including from Malaysian Pengkid official website and through snowballing technique. Results show that Pengkids in this study have wide and various categories of interpersonal relationships and received several types of social supports from their interpersonal relationships. This indicates that Pengkid in this study were well-accepted by their social circle and maintained a good relationship with individuals who knew and are aware of their sexual orientation. Close friends and romantic partners were the main sources of all types of support for this group. Other categories of interpersonal relationships also provide some social supports to this group but of lesser quality and quantity compared to these two. Findings from this research suggest the unique and different role is played by different individuals in one social network. This study contributes to the same sex sexual orientation on this particular group. &nbsp
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