29 research outputs found
National mortality burden due to communicable, non-communicable, and other diseases in Ethiopia, 1990-2015: findings from the Global Burden of Disease Study 2015
No full textPublished online: 21 July 2017Background: Ethiopia lacks a complete vital registration system that would assist in measuring disease burden and risk factors. We used the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) estimates to describe the mortality burden from communicable, non-communicable, and other diseases in Ethiopia over the last 25 years. Methods: GBD 2015 mainly used cause of death ensemble modeling to measure causes of death by age, sex, and year for 195 countries. We report numbers of deaths and rates of years of life lost (YLL) for communicable, maternal, neonatal, and nutritional (CMNN) disorders, non-communicable diseases (NCDs), and injuries with 95% uncertainty intervals (UI) for Ethiopia from 1990 to 2015. Results: CMNN causes of death have declined by 65% in the last two-and-a-half decades. Injury-related causes of death have also decreased by 70%. Deaths due to NCDs declined by 37% during the same period. Ethiopia showed a faster decline in the burden of four out of the five leading causes of age-standardized premature mortality rates when compared to the overall sub-Saharan African region and the Eastern sub-Saharan African region: lower respiratory infections, tuberculosis, HIV/AIDS, and diarrheal diseases; however, the same could not be said for ischemic heart disease and other NCDs. Non-communicable diseases, together, were the leading causes of age-standardized mortality rates, whereas CMNN diseases were leading causes of premature mortality in 2015. Although lower respiratory infections, tuberculosis, and diarrheal disease were the leading causes of age-standardized death rates, they showed major declines from 1990 to 2015. Neonatal encephalopathy, iron-deficiency anemia, protein-energy malnutrition, and preterm birth complications also showed more than a 50% reduction in burden. HIV/AIDS-related deaths have also decreased by 70% since 2005. Ischemic heart disease, hemorrhagic stroke, and ischemic stroke were among the top causes of premature mortality and age-standardized death rates in Ethiopia in 2015. Conclusions: Ethiopia has been successful in reducing deaths related to communicable, maternal, neonatal, and nutritional deficiency diseases and injuries by 65%, despite unacceptably high maternal and neonatal mortality rates. However, the country’s performance regarding non-communicable diseases, including cardiovascular disease, diabetes, cancer, and chronic respiratory disease, was minimal, causing these diseases to join the leading causes of premature mortality and death rates in 2015. While the country is progressing toward universal health coverage, prevention and control strategies in Ethiopia should consider the double burden of common infectious diseases and non-communicable diseases: lower respiratory infections, diarrhea, tuberculosis, HIV/AIDS, cardiovascular disease, cancer, and diabetes. Prevention and control strategies should also pay special attention to the leading causes of premature mortality and death rates caused by non-communicable diseases: cardiovascular disease, cancer, and diabetes. Measuring further progress requires a data revolution in generating, managing, analyzing, and using data for decision-making and the creation of a full vital registration system in the country.Awoke Misganaw, Tilahun N. Haregu, Kebede Deribe, Gizachew Assefa Tessema, Amare Deribew, Yohannes Adama Melaku, Azmeraw T. Amare, Semaw Ferede Abera, Molla Gedefaw, Muluken Dessalegn, Yihunie Lakew, Tolesa Bekele, Mesoud Mohammed, Biruck Desalegn Yirsaw, Solomon Abrha Damtew, Kristopher J. Krohn, Tom Achoki, Jed Blore, Yibeltal Assefa and Mohsen Naghav
Correction: Addressing a missed opportunity for contraceptive use during the extended postpartum period by integrating it with infant immunization services in Sidama Region, Ethiopia: A quasi-experimental study.
No full text[This corrects the article DOI: 10.1371/journal.pgph.0003236.]
Addressing a missed opportunity for contraceptive use during the extended postpartum period by integrating it with infant immunization services in Sidama Region, Ethiopia: A quasi-experimental study
No full textAddressing a missed opportunity for contraceptive use during the extended postpartum period by integrating it with infant immunization services in Sidama Region, Ethiopia: A quasi-experimental study.
No full textGlobally, unmet need for postpartum family planning is high. However, immunization services are among the most widely utilized health services. Establishing systematic screening, counseling, and referral systems from different contact points, particularly from EPI units may improve postpartum family planning uptake. Hence, this study aimed to assess the effect of counseling for family planning at EPI units on contraceptive uptake during the extended post-partum period. A before-and-after type of quasi-experimental study was conducted in 8 purposively selected primary health care units in Sidama region, Ethiopia. All mothers visiting the selected health facilities for infant immunization services from February 06 to August 30, 2020, were screened, counseled, and referred for family planning. A structured interviewer-administered questionnaire was used to collect data from 1421 randomly selected mothers (717 for pre-intervention and 704 post-intervention phases). EpiData version 3.1 and SPSS version 22 were used for data entry and analysis. The effect of the intervention was assessed using multivariable logistic regression analysis adjusting for the effects of potential confounders. P value < 0.05 was considered statistically significant. The contraceptive utilization rate before intervention was 72.7% with 95% CI (69.5, 75.9). It was 91.9%, 95% CI (89.8%, 93.9%) after the intervention. Utilization of contraceptive pills increased from 4.3% to 6.9%, injectables from 52.4% to 57.5%, implants from 12.8% to 22.9%, and IUCD from 3.2% to 5.0% after the intervention. After adjusting for the effect of possible confounding variables, screening, counseling, and referring mothers for family planning at infant immunization units significantly increases the contraceptive utilization rate among mothers presented for infant immunization services(AOR = 5.83, 95% CI: 4.02, 8.46). Screening, counseling, and referring mothers for family planning services at infant immunization units significantly increases postpartum contraceptive uptake. Integrating family planning messages with infant immunization services is recommended. Trial registration: ClinicalTrials.gov Identifier: NCT04767139 (Registered on 23/02/2021)
Development of Brown Seed and Release of “Biradama” Tef Variety for Potential Areas of Amhara Region and Beyond
No full textBrown seed tef variety development did not get much attention as white seed in tef improvement program in Ethiopia. However, brown seed tef is locally demanded for home consumption and foreign markets. It has wider genetic variability that can be exploited in tef improvement program. Therefore, the study was conducted to develop high yielding brown seed tef variety with desirable agronomic and quality traits. Eighteen tef genotypes with standard and local checks were used for this study. The study was conducted at Adet (2019 and 2020), Mota (2019 and 2020), Takusa (2019 and 2020) and Finote Selam (2020) in Amhara region with a total of seven environments. A randomized complete block design with 3 replications was used in this experiment. The analysis of variances showed significant differences for the evaluated traits in genotypes, environments and genotypes by environment interaction. The genotype Accession # 236756-3 is a stable genotype than theother tested genotypes. The grain and straw yield performance of the genotype accession # 236756-3 was 2529 kg.ha-1 and 6040 kg.ha-1, respectively. It had 14.3% and 25.2% grain yield advantage over standard check “Filagot”, and the farmer’s variety, respectively. In addition, it had 13.6% and 19.4 % straw yield advantage over “Filagot” (standard check) and the farmer’s variety, respectively. A variety verification trial of the genotype accession # 236756-3 was conducted in test locations with a standard check (“Filagot”) and the farmer’s variety. The field performance of the verification trial was evaluated by National Technical Committee and released the variety for large production in tef production potential areas of Amhara Region and similar agro-ecologies of Ethiopia with a local name ‘Biradama”. This newly released variety can be used as parental material in the genetic improvements of tef.
Burden and its associated factors of neonatal necrotizing enter colitis among neonates admitted in neonatal intensive care unit in Ethiopia. A systematic review and meta-analysis
No full textNeonatal Necrotizing enterocolitis is the most critical and recurrent gastrointestinal disorder in neonatal intensive care units. Although the overall mortality extends to 50 % related to necrotizing enterocolitis, it can approach 100 % with perforation, peritonitis and sepsis complications. It is the first step to planning management approaches that can contribute to decreasing long term morbidity and mortality. The aim of this systematic review and meta-analysis was to assess the prevalence and its determinant factors of necrotizing enterocolitis among admitted neonates in Ethiopia. The procedure of this systematic review and meta-analysis was registered at the Prospero with a registration number of CRD42023409175. Universal online databases such as PubMed, Cochrane, Google, Google Scholar, SCOPUS, and Web of science and Global health were used to search for articles. Data extraction was commenced with Microsoft Excel and STATA17 was used to conduct the Meta-Analysis. Random effect model analysis was considered when there was evidence of heterogeneity among the studies. The overall pooled prevalence of neonatal necrotizing enterocolitis was 14.4 % (95 % CI; 7.04, 21.85, I2 = 95.80 %, p = 0.000). The pooled odds ratio of Birth weight (AOR = 3.75 (95 % CI; 1.72, 5.79), Apgar score (AOR = 2.37 (95 % CI; 1.83, 2.91), maternal infection (AOR = 5.24 (95 % CI; 4.04, 6.45) and prolonged labor (AOR = 2.70 (95 % CI; 1.65, 3.74) had significant statistical association with neonatal necrotizing enterocolitis. This finding concluded that high prevalence and multiple determinant factors of neonatal necrotizing enterocolitis in Ethiopia. This finding recommend that neonatal care programs prioritize targeting maternal infection prevention, improved labor management, and enhanced care for low birth weight neonates and those with low Apgar scores to decrease the unacceptably high burden of neonatal necrotizing enterocolitis and its devastating consequences
Metabolic syndrome among type 2 diabetic patients in Sub-Saharan African countries: A systematic review and meta-analysis.
No full textPubMed, Web of Science, African Journals Online, Google Scholar, Scopus, and Wiley Online Library databases from inception to April 27, 2020 were searched to identify relevant studies. The I2 statistic was used to check heterogeneity across the included studies. DerSimonian and Laird random-effects model was applied to estimate pooled effect size, and 95% confidence interval across studies. A funnel plot and Egger's regression test were used to determine the presence of publication bias. Sensitivity analysis was deployed to determine the effect of a single study on the overall estimation. All statistical analyses were done using STATA™ Version 14 software
Association between antenatal care follow-up and institutional delivery service utilization: Analysis of 2016 Ethiopia demographic and health survey
No full text© 2019 The Author(s). Background: Globally, the magnitude of maternal mortality is the major public health problem. Nearly all (99%) of maternal deaths occur in low- and middle-income countries. Of which 66% occur in sub-Saharan Africa. Institutional delivery under the hygienic environment with the necessary skills and equipment promotes to identify and treat complications, infections, and the death of the mother and baby. In Ethiopia, the utilization of maternal health services is very low. For instance, 62% of women had antenatal care utilization during pregnancy while only 26% of women utilize institutions for delivery in 2016. Therefore, this study examined the association between antenatal care follow up and intestinal delivery among a nationally representative woman in Ethiopia. Methods: A cross-sectional study design was used to examine 7575 women from the 2016 Ethiopia Demographic and Health Survey. Both descriptive and inferential statistics were utilized. Variables in the bivariate logistic regression with p-value \u3c 0.2 were entered into the multivariable logistic regression. Odds ratios and corresponding 95% confidence intervals (CI) were reported. In the multivariable analysis, variables with p-value \u3c 0.05 were considered as statistically significant. Results: The prevalence of institutional delivery service utilization for last childbirth was 11.3%. In comparison with women with no antenatal care visits, the multivariable odds ratio (95% confidence interval) of institutional delivery among those who attend one to three and four or more antenatal care visit were 2.49 (1.66, 3.74) and 3.90 (2.60, 5.84), respectively. Other factors significantly associated with institutional delivery include urban residence 2.25 (1.44, 3.51), complete primary education 3.22 (2.09, 4.98), complete secondary or higher education 1.59 (1.16, 2.17), poorer household wealth index 2.57 (1.57, 4.20), middle household wealth index 1.63 (1.05, 2.52), and richer household wealth index 1.56(1.03, 2.58). Conclusion: Antenatal care follow-up was significantly associated with institutional delivery service utilization. As the number of antenatal care visits increased the odds of facility delivery increased. Thus, improved access and utilization of antenatal care can be an effective strategy to increase institutional deliveries and optimal maternal and child health outcomes
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, The Author(s)
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017 (Nature Medicine, (2020), 26, 5, (750-759), 10.1038/s41591-020-0807-6)
No full textAn amendment to this paper has been published and can be accessed via a link at the top of the paper. © 2020, The Author(s)
