1,721,528 research outputs found
Bivalirudin in Patients Undergoing PCI: State of Art and Future Perspectives
Full text linkAcute coronary syndrome (ACS) represents the most common cause of death worldwide. Percutaneous coronary intervention (PCI) is the management of choice in patients with ACS and occurrence of intra-procedural thrombotic complications are an independent predictor of mortality and other major adverse cardiovascular events in patients undergoing PCI. According to current guideline, anticoagulation therapy is indicated during PCI in order to reduce the risk of thrombotic complications such as stent thrombosis. Among currently available anticoagulant drugs, bivalirudin demonstrates a lower incidence of bleeding risk, despite it is associated with an increased risk of stent thrombosis. The aim of this paper is to discuss the pharmacology of bivalirudin and the clinical evidences of its use in patients undergoing PCI for ACS
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Spontaneous coronary artery dissection in a young woman with polycystic ovarian syndrome
No full textVariations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Pseudomesoteliomatous angiosarcoma: a pleuropulmonary lesion simulating malignant pleural mesothelioma
No full textDefinition of differential seismic input motions for out-of-plane dynamic testing of unreinforced masonry gable walls considering different roof configurations
No full textUnreinforced masonry gables are widely present in low-rise existing buildings and are particularly vulnerable to seismic events, as demonstrated by the several observed out-of-plane collapses of these structural elements during earthquakes. Since the structural behaviour of gable walls has been scarcely investigated in the literature, a large-scale testing programme (ERIES-SUPREME) has been initiated by research institutions in the Netherlands (TU Delft, TNO) and Italy (EUCENTRE, University of Pavia, IUSS Pavia), to dynamically characterise the gable out-of-plane seismic response. Shake-table tests on full-scale masonry gables are being conducted at the 9D LAB facility in EUCENTRE (Pavia, Italy), incorporating the effects of different ground motions, structures and roof stiffnesses. This facility features both a top and a bottom shake table, allowing for separate input motions: therefore, the effect of the roof dynamic behaviour can be accounted for by applying differential signals. This work presents the procedure used to define such input motions. While for tectonic signals direct earthquake recordings at floor level are accessible from existing monitored masonry buildings in Italy, for induced signals in the Netherlands such data are not available. Thus, in the latter case, numerical analyses are conducted considering a reference unreinforced masonry building subjected to induced earthquakes, with three roof configurations representing flexible, semi-flexible, and stiff diaphragms. Based on the obtained outcomes, input signals are derived for both induced and tectonic earthquake scenarios, leading to the final definition of the testing protocol for the ERIES-SUPREME experimental campaign. The findings of this study are also broadly applicable for the derivation of input motions in the planning of benchmark experiments where parts of the structural system cannot be explicitly reproduced due to testing constraints
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Analisi preliminari sulla tossicità di essudati di Arenicola marina (Linnaeus, 1758) (Annelida: Arenicolidae)
No full textThe effects of the exudate (crude and its organic extracts) obtained by Arenicola marina
(Annelida: Arenicolidae) were evaluated through acute toxicity bioassays on the annelid Dinophilus
gyrociliatus. Preliminary chemical analyses were also performed. The exudate and its n-buthanol
extract were toxic (LC50 24h=12%, c.i.=9.7-14.7% and 31.7 mg l-1, c.i.=27.9-36 mg l-1, respectively). The
results support the hypothesis that the exudate could be involved in the chemical defence of A. marina
- …
