104 research outputs found
Rzeki Adda i Pad jako miejsca pamięci literackiej w idylli Adda Alessandra Manzoniego
No full textThe article aims at analyzing the idyll Adda by Alessandro Manzoni, one of the greatest representatives of the Italian Romanticism. The Adda is one of the early, neoclassical works of Manzoni. The young author presents the monologue of the nymph Adda, the goddess of the river of the same name, who invites to her humble kingdom the poet Vincenzo Monti, born on the banks of the great Po. The rivers Adda and Po are presented in the Manzoni’s idyll as the places of the literary memory
Gebel Adda and its environs: 50 years on
No full text[First paragraph] Following the 2015 Kirwan Memorial Lecture delivered by Dr Grzymski (see also Grzymski 2010) this
further brief article concerning the ARCE excavations at Gebel Adda has been prepared drawing on
personal records of one of the participants (RH) and information provided by Horst Jaritz and the late
Richard Edlund1 relating to a range of archaeological material in and around Gebel Adda. This
summarises a much more extensive series of notes prepared by the first author (RH) along with
drawings and photographs. With the aid of aerial photographs from the collections of George Gerster
a composite map of Gebel Adda and its environs has also been prepared (fig.1) indicating some of the
main sites in and around the ARCE concession including the outlines of the main cemeteries. It is
hoped that this may be useful for those working with the various published reports which lack
supporting mapping/plans
Gebel Adda and its environs: 50 years on
No full text[First paragraph] Following the 2015 Kirwan Memorial Lecture delivered by Dr Grzymski (see also Grzymski 2010) this
further brief article concerning the ARCE excavations at Gebel Adda has been prepared drawing on
personal records of one of the participants (RH) and information provided by Horst Jaritz and the late
Richard Edlund1 relating to a range of archaeological material in and around Gebel Adda. This
summarises a much more extensive series of notes prepared by the first author (RH) along with
drawings and photographs. With the aid of aerial photographs from the collections of George Gerster
a composite map of Gebel Adda and its environs has also been prepared (fig.1) indicating some of the
main sites in and around the ARCE concession including the outlines of the main cemeteries. It is
hoped that this may be useful for those working with the various published reports which lack
supporting mapping/plans
Gebel Adda Cemeteries 3 and 4 (1963-1964)
No full textThe excavation team of the American Research Center in
Egypt, under the direction of Dr Nicholas B. Millet, first
arrived at Gebel Adda in January 1963, for what were to
be four excavation seasons. Excavations started in Cemetery
1, which included numerous tumuli, extending over
c. 450m from the southern end of the concession to north
east of the Citadel (Millet 1963). Work began in the south
of the cemetery and excavated c. 127 tumuli, dated to the
later post-Meroitic (X-Group) period. In the same area,
amongst the tumuli, c. 30 medieval (Christian) graves were
also found, thought likely to date to the earliest period
of Christianization at Gebel Adda. Four examples of the
double domed mud-brick tombs of the post-medieval
(Islamic) period were also excavated in Cemetery One.
In March 1963 excavations were also begun in Cemetery
3, lying some 160m south east of the Citadel hill (Figure
1, Plate 1), an area covered with much wind-blown sand,
exposing c. 400 tombs during the first season (Millet 1963,
154). This work was continued in the second (1963-1964)
season (Millet 1964) and the third season, for which no
preliminary report was published (see also Millet 1967b;
1968; 2005; Grzymski 2010).
Some preliminary observations of this area were published
as the excavations were still underway by Millet (Millet 1963;
1964), but little else relating to this important work has yet
been published. However, the first author (RH), as a member
of the ARCE team, can throw some further light on some features of the excavations. Most importantly, having carried
out much of the original preparation of site plans, it has been
possible to reconstruct here some partial plans of Cemetery
3, which together with personal photographs of the site
provide some useful new information concerning this part of
the Gebel Adda excavations. Until the surviving site archives
are more fully studied, and hopefully published, this brief
report, as with previous reports (Huber and Edwards 2009;
2010), can provide a few further insights into the fascinating
and clearly complex history of the Gebel Adda cemeteries
Improved diastolic function in type 2 diabetes after a six month liraglutide treatment
No full textAbstractAimsTo investigate whether liraglutide improves diastolic function in type 2 diabetes.MethodsThirty-seven patients with type 2 diabetes who began liraglutide therapy between June 2013 and May 2014 were enrolled in this observational, prospective study. 26 patients received liraglutide therapy for at least 6months. The remaining 11 patients withdrew from liraglutide therapy during the first month, were started on other hypoglycaemic therapies and formed the control group. Anthropometric, metabolic and echocardiographic parameters including pulsed wave tissue Doppler imaging were evaluated at baseline and at 6months.ResultsIn the liraglutide group the early diastolic mitral annulus velocity on the lateral (e-lat) and medial (e-med) sides of the mitral annulus increased from 9.2±3.4 to 11.6±4.7cm/s (p<0.001) and from 6.9±1.7 to 8.4±2.6cm/s (p<0.003), respectively. The ratio of early-to-late velocities on the lateral and medial sides of the mitral annulus increased from 0.7±0.3 to 0.9±0.4 (p<0.001) and from 0.5±0.1 to 0.6±0.1 (p<0.02), respectively. The ratio of early diastolic mitral inflow velocity to early diastolic myocardial relaxation velocity decreased from 10.7±4.3 to 8.5±2.5 (p<0.005). No improvements in diastolic function was detected in the control group. Glucose control improved similarly in both groups: HA1bc −1.5% (−17mmol/mol) vs −1.3% (−14mmol/mol), p=0.67.ConclusionsIn patients with type 2 diabetes, 6months liraglutide treatment was associated with a significant improvement in diastolic function
Organisation and management of clinical research in French intensive care units : a focus on clinical research professions
No full textLa recherche clinique une des pierres angulaires de la médecine et de l'activité des hôpitaux a pour but l'évaluation de nouvelles pratiques et de nouveaux traitements. Elle doit répondre à des exigences éthiques et réglementaires précises accompagnées de bonnes pratiques.Pour répondre à ces exigences, elle s'est professionnalisée au fil des années. Toutefois, peu d'études sur son organisation et ses métiers ont été réalisées. L'objectif de nos travaux était d'étudier l'organisation de la recherche clinique afin d'identifier d'éventuelles disparités des pratiques et proposer des axes d'amélioration.Bien que l'ensemble des services d'un hôpital accueillent des activités de recherche clinique, nos travaux se sont focalisés sur les unités de soins critiques, services prenant en charge les patients aux affections les plus graves et susceptibles de participer à de nombreuses thématiques de recherche.La première partie de nos travaux a consisté à la réalisation d'une revue exploratoire de la littérature afin de faire un état des lieux des recherches menées sur l'organisation des métiers de la recherche clinique. Le faible nombre des études recensées et l'hétérogénéité des organisations entre les pays voire au sein d'un même pays, ont montré l'insuffisance des connaissances disponibles sur le sujet. La seconde partie de nos travaux a permis - par une enquête en ligne auprès de professionnels impliqués dans la recherche clinique - de faire un état des lieux des métiers de la recherche clinique dans les unités de soins critiques en France. En plus d'avoir confirmé l'hétérogénéité des profils du personnel, notamment en matière de la formation initiale, nous avons montré que la polyvalence et l'autonomie étaient perçues comme l'aspect le plus apprécié des personnels, alors que le manque de temps ou de reconnaissance étaient perçus négativement.L'ensemble de ces résultats nous donnent la possibilité de continuer à enrichir ce sujet avec des perspectives d'étendre notre recherche au plan international et de proposer des pistes de réformes de structurations des formations du personnel de recherche clinique.Clinical research is one of the cornerstones of medicine and hospital activity. Its main aim is to evaluate new practices and treatments, and it must meet precise ethical and regulatory requirements, as well as good practice.To meet these requirements, it has become professional over the years. However, few studies have been carried out on the organisation of clinical research and the professions involved. The aim of our work was to study the organisation of clinical research in order to identify any disparities in practice and suggest areas for improvement.Although clinical research activities are carried out in all hospital departments, our work has focused on Intensive care units, where patients with the most serious conditions are treated, and which are likely to be involved in a wide range of research themes.The first part of our work consisted of a scoping review of the literature in order to take stock of the research carried out on the organisation of clinical research professions. The small number of studies identified and the heterogeneity of organisations between countries, and even within the same country, demonstrated the inadequacy of the knowledge available on the subject. The second part of our work - an online survey of professionals involved in clinical research - enabled us to take stock of the clinical research professions in Intensive care units in France. As well as confirming the heterogeneity of staff profiles, particularly in terms of initial training, we showed that multivalence and autonomy were perceived as the aspects most appreciated by the professional, whereas lack of time or recognition were perceived negatively.Taken together, these results give us the opportunity to continue enriching this subject, with the prospect of extending our research internationally and proposing ways of reforming the structure of training for clinical research professional
Organisation et gestion de la recherche clinique dans les réanimations françaises : regard sur les métiers de la recherche clinique
No full textClinical research is one of the cornerstones of medicine and hospital activity. Its main aim is to evaluate new practices and treatments, and it must meet precise ethical and regulatory requirements, as well as good practice.To meet these requirements, it has become professional over the years. However, few studies have been carried out on the organisation of clinical research and the professions involved. The aim of our work was to study the organisation of clinical research in order to identify any disparities in practice and suggest areas for improvement.Although clinical research activities are carried out in all hospital departments, our work has focused on Intensive care units, where patients with the most serious conditions are treated, and which are likely to be involved in a wide range of research themes.The first part of our work consisted of a scoping review of the literature in order to take stock of the research carried out on the organisation of clinical research professions. The small number of studies identified and the heterogeneity of organisations between countries, and even within the same country, demonstrated the inadequacy of the knowledge available on the subject. The second part of our work - an online survey of professionals involved in clinical research - enabled us to take stock of the clinical research professions in Intensive care units in France. As well as confirming the heterogeneity of staff profiles, particularly in terms of initial training, we showed that multivalence and autonomy were perceived as the aspects most appreciated by the professional, whereas lack of time or recognition were perceived negatively.Taken together, these results give us the opportunity to continue enriching this subject, with the prospect of extending our research internationally and proposing ways of reforming the structure of training for clinical research professional.La recherche clinique une des pierres angulaires de la médecine et de l'activité des hôpitaux a pour but l'évaluation de nouvelles pratiques et de nouveaux traitements. Elle doit répondre à des exigences éthiques et réglementaires précises accompagnées de bonnes pratiques.Pour répondre à ces exigences, elle s'est professionnalisée au fil des années. Toutefois, peu d'études sur son organisation et ses métiers ont été réalisées. L'objectif de nos travaux était d'étudier l'organisation de la recherche clinique afin d'identifier d'éventuelles disparités des pratiques et proposer des axes d'amélioration.Bien que l'ensemble des services d'un hôpital accueillent des activités de recherche clinique, nos travaux se sont focalisés sur les unités de soins critiques, services prenant en charge les patients aux affections les plus graves et susceptibles de participer à de nombreuses thématiques de recherche.La première partie de nos travaux a consisté à la réalisation d'une revue exploratoire de la littérature afin de faire un état des lieux des recherches menées sur l'organisation des métiers de la recherche clinique. Le faible nombre des études recensées et l'hétérogénéité des organisations entre les pays voire au sein d'un même pays, ont montré l'insuffisance des connaissances disponibles sur le sujet. La seconde partie de nos travaux a permis - par une enquête en ligne auprès de professionnels impliqués dans la recherche clinique - de faire un état des lieux des métiers de la recherche clinique dans les unités de soins critiques en France. En plus d'avoir confirmé l'hétérogénéité des profils du personnel, notamment en matière de la formation initiale, nous avons montré que la polyvalence et l'autonomie étaient perçues comme l'aspect le plus apprécié des personnels, alors que le manque de temps ou de reconnaissance étaient perçus négativement.L'ensemble de ces résultats nous donnent la possibilité de continuer à enrichir ce sujet avec des perspectives d'étendre notre recherche au plan international et de proposer des pistes de réformes de structurations des formations du personnel de recherche clinique
Organisation et gestion de la recherche clinique dans les réanimations françaises : regard sur les métiers de la recherche clinique
No full textClinical research is one of the cornerstones of medicine and hospital activity. Its main aim is to evaluate new practices and treatments, and it must meet precise ethical and regulatory requirements, as well as good practice.To meet these requirements, it has become professional over the years. However, few studies have been carried out on the organisation of clinical research and the professions involved. The aim of our work was to study the organisation of clinical research in order to identify any disparities in practice and suggest areas for improvement.Although clinical research activities are carried out in all hospital departments, our work has focused on Intensive care units, where patients with the most serious conditions are treated, and which are likely to be involved in a wide range of research themes.The first part of our work consisted of a scoping review of the literature in order to take stock of the research carried out on the organisation of clinical research professions. The small number of studies identified and the heterogeneity of organisations between countries, and even within the same country, demonstrated the inadequacy of the knowledge available on the subject. The second part of our work - an online survey of professionals involved in clinical research - enabled us to take stock of the clinical research professions in Intensive care units in France. As well as confirming the heterogeneity of staff profiles, particularly in terms of initial training, we showed that multivalence and autonomy were perceived as the aspects most appreciated by the professional, whereas lack of time or recognition were perceived negatively.Taken together, these results give us the opportunity to continue enriching this subject, with the prospect of extending our research internationally and proposing ways of reforming the structure of training for clinical research professional.La recherche clinique une des pierres angulaires de la médecine et de l'activité des hôpitaux a pour but l'évaluation de nouvelles pratiques et de nouveaux traitements. Elle doit répondre à des exigences éthiques et réglementaires précises accompagnées de bonnes pratiques.Pour répondre à ces exigences, elle s'est professionnalisée au fil des années. Toutefois, peu d'études sur son organisation et ses métiers ont été réalisées. L'objectif de nos travaux était d'étudier l'organisation de la recherche clinique afin d'identifier d'éventuelles disparités des pratiques et proposer des axes d'amélioration.Bien que l'ensemble des services d'un hôpital accueillent des activités de recherche clinique, nos travaux se sont focalisés sur les unités de soins critiques, services prenant en charge les patients aux affections les plus graves et susceptibles de participer à de nombreuses thématiques de recherche.La première partie de nos travaux a consisté à la réalisation d'une revue exploratoire de la littérature afin de faire un état des lieux des recherches menées sur l'organisation des métiers de la recherche clinique. Le faible nombre des études recensées et l'hétérogénéité des organisations entre les pays voire au sein d'un même pays, ont montré l'insuffisance des connaissances disponibles sur le sujet. La seconde partie de nos travaux a permis - par une enquête en ligne auprès de professionnels impliqués dans la recherche clinique - de faire un état des lieux des métiers de la recherche clinique dans les unités de soins critiques en France. En plus d'avoir confirmé l'hétérogénéité des profils du personnel, notamment en matière de la formation initiale, nous avons montré que la polyvalence et l'autonomie étaient perçues comme l'aspect le plus apprécié des personnels, alors que le manque de temps ou de reconnaissance étaient perçus négativement.L'ensemble de ces résultats nous donnent la possibilité de continuer à enrichir ce sujet avec des perspectives d'étendre notre recherche au plan international et de proposer des pistes de réformes de structurations des formations du personnel de recherche clinique
Clustering-Based Identification of Precursors of Extreme Events in Chaotic Systems
No full textAbrupt and rapid high-amplitude changes in a dynamical system’s states known as extreme events appear in many processes occurring in nature, such as drastic climate patterns, rogue waves, or avalanches. These events often entail catastrophic effects, therefore their description and prediction is of great importance. However, because of their chaotic nature, their modelling represents a great challenge up to this day. The applicability of a data-driven modularity-based clustering technique to identify precursors of rare and extreme events in chaotic systems is here explored. The proposed identification framework based on clustering of system states, probability transition matrices and state space tessellation was developed and tested on two different chaotic systems that exhibit extreme events: the Moehliss-Faisst-Eckhardt model of self-sustained turbulence and the 2D Kolmogorov flow. Both exhibit extreme events in the form of bursts in kinetic energy and dissipation. It is shown that the proposed framework provides a way to identify pathways towards extreme events and predict their occurrence from a probabilistic standpoint. The clustering algorithm correctly identifies the precursor states leading to extreme events and allows for a statistical description of the system’s states and its precursors to extreme events.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Aerodynamic
Proceedings Transborder Library Forum 2007 : bridging the digital divide : crossing all borders = Memorias Foro Transfronterizo de Bibliotecas 2007 : cerrando la brecha digital : cruzando todas las fronteras
No full textIt is with great pleasure that we present this edition of the Proceedings of the Transborder Library Forum (Foro). The 2007 Transborder Library Forum was held at Arizona State University in Tempe, Arizona in February, 2007. We are pleased that there will be both a print edition and an online edition. Editing has been kept to a minimum to preserve the intent of the author in the language the paper was presented. The theme for the 2007 Foro was Bridging the Digital Divide. Topics ranged from international copyright issues to getting information to students in widely dispersed communities with little or no infrastructure except the Internet. While most attendees and speakers were from the USA and Mexico, we also had some from Uganda, Kenya, Hungary, and the West Indies
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