1,721,178 research outputs found

    Contemporary indications for upfront total pancreatectomy

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    Currently, advances in surgical techniques, improvements in perioperative care, new formulations of intermediate and long-acting insulin and of modern pancreatic enzyme preparations have allowed obtaining good short and long-term results and quality of life, especially in high-volume centres in performing total pancreatectomy (TP).Thus, the surgeon’s fear in performing TP is not justified and total pancreatectomy can be considered a viable option in selected patients in high-volume centres. The aim of this review was to define the current indications for this procedure, in particular for upfront TP, considering not only the pancreatic disease, but also the surgical approach (open, mini-invasive) and the relationship with vascular resection

    Late postpancreatectomy hemorrhage after pancreaticoduodenectomy: is it possible to recognize risk factors ?

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    CONTEXT: Post-pancreatectomy hemorrhage is one of the most common complications after pancreaticoduodenectomy. OBJECTIVE: To evaluate the late post-pancreatectomy hemorrhage rate according to the International Study Group of Pancreatic Surgery criteria and to recognize factors related to its onset. METHODS: A prospective study of 113 patients who underwent pancreaticoduodenectomy was conducted. Late post-pancreatectomy hemorrhage was defined according to the criteria of the International Study Group of Pancreatic Surgery. Demographic, clinical, surgical and pathological data were considered and related to late post-pancreatectomy hemorrhage. RESULTS: Thirty-one (27.4%) patients had a post-pancreatectomy hemorrhage. Twenty-five (22.1%) patients developed late post-pancreatectomy hemorrhage: 19 (16.8%) grade B, 6 (5.3%) grade C. Surgical re-operation was performed in 2 out of the 25 cases with late post-pancreatectomy hemorrhage (8.0%) grade C associated with postoperative pancreatic fistula. At univariate analysis, the only factor significantly related to late post-pancreatectomy hemorrhage was postoperative pancreatic fistula (P<0.001). Multivariate analysis underlined that the severity of postoperative pancreatic fistula (P<0.001) and pancreatic anastomosis (P=0.049) independently increased the risk of late hemorrhage. CONCLUSION: In patients undergoing pancreaticoduodenectomy, the criteria introduced by International Study Group of Pancreatic Surgery to define late postpancreatectomy hemorrhage are related to a higher incidence of hemorrhage than previously detected because they considered also mild hemorrhage

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    I patti per la sicurezza

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    I Patti per la sicurezza rappresentano uno strumento non vincolante volto a incentivare le politiche per la sicurezza urbana incrementando la collaborazione istituzionale dei vari livelli di governo. La ricerca muove dalla ricostruzione del quadro normativo in cui i Patti si collocano e attraverso un'analisi empirica mira a sottoporre a verifica l'utilità e l'efficacia dello strumento pattizio

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Late postpancreatectomy hemorrhage after pancreaticoduodenectomy: is it possible to recognize risk factors?

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    CONTEXT: Post-pancreatectomy hemorrhage is one of the most common complications after pancreaticoduodenectomy. OBJECTIVE: To evaluate the late post-pancreatectomy hemorrhage rate according to the International Study Group of Pancreatic Surgery criteria and to recognize factors related to its onset. METHODS: A prospective study of 113 patients who underwent pancreaticoduodenectomy was conducted. Late post-pancreatectomy hemorrhage was defined according to the criteria of the International Study Group of Pancreatic Surgery. Demographic, clinical, surgical and pathological data were considered and related to late post-pancreatectomy hemorrhage. RESULTS: Thirty-one (27.4%) patients had a post-pancreatectomy hemorrhage. Twenty-five (22.1%) patients developed late post-pancreatectomy hemorrhage: 19 (16.8%) grade B, 6 (5.3%) grade C. Surgical re-operation was performed in 2 out of the 25 cases with late post-pancreatectomy hemorrhage (8.0%) grade C associated with postoperative pancreatic fistula. At univariate analysis, the only factor significantly related to late post-pancreatectomy hemorrhage was postoperative pancreatic fistula (P<0.001). Multivariate analysis underlined that the severity of postoperative pancreatic fistula (P<0.001) and pancreatic anastomosis (P=0.049) independently increased the risk of late hemorrhage. CONCLUSION: In patients undergoing pancreaticoduodenectomy, the criteria introduced by International Study Group of Pancreatic Surgery to define late postpancreatectomy hemorrhage are related to a higher incidence of hemorrhage than previously detected because they considered also mild hemorrhage

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Patologia litiasica della colecisti e delle vie biliari. Testo di “Chirurgia Generale” a cura di Minni F. Edizioni CEA. Zanichelli 2019.

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    Il sistema biliare rappresenta una complessa unità funzionale finalizzata al trasporto della bile e alla sua concentrazione (Figura 16.1). La bile, prodotta dagli epatociti, viene convogliata, attraverso un sistema di dotti di calibro crescente, dall’interno del fegato fino alla via biliare extraepatica, raggiungendo la colecisti (o cistifellea), dove verrà concentrata e dalla quale verrà successivamente rilasciata per essere riversata, attraverso il coledoco, in duodeno. Le vie biliari sono convenzionalmente suddivise in vie biliari intraepatiche ed extraepatiche. Mentre le vie biliari intraepatiche sono caratterizzate da ramificazioni successive, che riflettono sostanzialmente la suddivisione funzionale del fegato in segmenti epatici, le vie biliari extraepatiche hanno un decorso grossomodo lineare e facilmente identificabile all’imaging con mezzo di contrasto. Le vie biliari extraepatiche, di pertinenza del presente capitolo, sono a loro volta suddivise in via biliare principale o epatocoledoco e via biliare accessoria. La prima è costituita dai due dotti epatici, destro e sinistro, confluenti nel dotto epatico comune, e poi nel dotto coledoco, che origina dalla confluenza tra dotto epatico comune e dotto cistico e prosegue sino allo sbocco nel lume intestinale a livello della papilla di Vater. La via biliare accessoria comprende la colecisti e il dotto cistico. Le vie biliari extraepatiche presentano una grande importanza chirurgica, sia per gli stretti rapporti anatomici con strutture vicine, sia per l’ampia varietà di alterazioni anatomiche che si possono riscontrare in tale distretto; la conoscenza di tali variabili anatomiche è fondamentale per evitare lesioni iatrogene in corso di questa chirurgi
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