1,720,953 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
The effect of mesenchymal stem cell-derived secretome on the coagulation of the blood plasma in species of veterinary interest.
No full textNegli ultimi decenni è stato dimostrato che l’efficacia terapeutica rigenerativa delle cellule staminali mesenchimali (MSC) è dovuta principalmente al loro biosecretoma (MSCs), che è costituito da un elevato numero di molecole bioattive rilasciate nello spazio extracellulare tramite secrezione. Queste sono sia in forma solubile che all’interno di vescicole extracellulari. Basandosi su queste premesse, Bari e colleghi hanno di recente presentato nell’articolo: “Pilot production of mesenchymal stem/stromal freeze-dried secretome for cell-free regenerative nanomedicine: a validated GMP-compliant process (2018). Cells 7.11, p. 190” una procedura innovativa e conforme alle norme GMP (Good Manufacturing Practice) per la produzione su larga scala di un prodotto farmaceutico costituito da MSCs di tessuto adiposo (AT-MSCs), che venendo sottoposto a liofilizzazione, viene denominato ‘Liosecretoma’. Questo prodotto, che può venire riscostituito mediante aggiunta di acqua sterile, è classificabile come un farmaco pronto all’uso, potenzialmente in grado di rimpiazzare le terapie a base di cellule staminali nel campo della medicina rigenerativa.
Poiché il processo coagulativo viene favorito dalla presenza di materiale micro e nano particolato e di sostanze procoagulanti che si trovano all’interno del liosecretoma, nel presente elaborato di tesi è stato verificato, per la prima volta in modo quantitativo, il suo effetto, in vitro, sulla formazione del coagulo di fibrina nelle specie canina ed equina. Lo sviluppo di torbidità causata dal processo coagulativo in funzione del tempo in campioni di plasma deprivato delle particelle endogene (mediante centrifugazione o ultracentrifugazione), è stata valutata attraverso l’aumento dell’assorbanza, sia in assenza che in presenza di quantità crescenti di liosecretoma. Le cinetiche di coagulazione seguono un andamento nel tempo che è descritto da funzioni sigmoidee a tre parametri, dalle quale è possibile valutare la fase di latenza del processo, il tempo in cui si realizza metà della coagulazione (t1/2 ) e, dalla pendenza al flesso, la velocità con cui il processo si realizza. Il valore finale di torbidità consente inoltre di ipotizzare differenti modalità di formazione del coagulo in funzione della velocità del suo processo di formazione.
In entrambe le specie si è evidenziata, all’aumentare della concentrazione di Liosecretoma, una significativa diminuzione dei t1/2 accompagnata da un altrettanto significativo incremento della velocità di formazione del coagulo (aumento della pendenza al flesso).
Queste variazioni sono risultate maggiori nella specie canina rispetto a quella equina. La coagulazione dei derivati del plasma indotta in tempi definiti dall’aggiunta di opportune quantità di liosecretoma, potrebbe quindi essere sfruttata anche in ambito clinico per la preparazione, ad esempio, di gel prodotti dalla coagulazione di derivati plasmatici pronti all’uso. Questi prodotti, applicati nella sede di danno permetterebbero alle sostanze utili presenti all’interno del Liosecretoma di rimanere localizzate in situ e di agire direttamente sul tessuto danneggiato.In recent decades, it has been demonstrated that the regenerative therapeutic efficacy of mesenchymal stem cells (MSCs) is primarily due to their biosecretome (MSCs), which consists of a high number of bioactive molecules released into the extracellular space by secretion. These molecules are both in soluble form and within extracellular vesicles. According to this, Bari and colleagues recently presented in their article: “Pilot production of mesenchymal stem/stromal freeze-dried secretome for cell-free regenerative nanomedicine: a validated GMP-compliant process (2018). Cells 7.11, p. 190” an innovative procedure, compliant with Good Manufacturing Practice (GMP) standards, for the large-scale production of a liophilized pharmaceutical product consisting of adipose tissue-derived MSCs (AT-MSCs), that has been called 'Lyosecretome'. This product, that is reconstituted by adding sterile water, can be classified as a ready-to-use drug, potentially capable of replacing stem cell-based therapies in the field of regenerative medicine.
As the coagulation process is facilitated by the presence of micro and nano particulate material and pro-coagulant substances that are also main constituents of the lyosecretome, this thesis investigates, for the first time quantitatively, its effect, in vitro, on the formation of fibrin clot in both canine and equine species. The development of turbidity caused by the coagulation process as a function of time in samples of plasma deprived of the endogenous particles (by centrifugation or ultracentrifugation) was evaluated spectrophotometrically as the increase of the absorbance, both in the absence and presence of increasing amounts of lyosecretome.
The coagulation kinetics follow a time course described by three-parameter sigmoid functions, that allow to assess the latency phase of the process, the time required to obtain one half of the coagulation (t1/2 ), and, from the slope at the inflection point, the velocity of the process. The final turbidity value also allows to hypothesize different models of both formation and molecular structure of the fibrin frame within the clot formation as functions of the velocity of the coagulation process. In both animal species, as the concentration of Lyosecretoma increased, a significant decrease of t1/2 was accompanied by an increase of the clot formation velocity (as determined by an increase of the slope at the inflection point). These variations were more pronounced in the canine species compared to the equine. The precise timing of the coagulation process, that is determined by the addition of appropriate quantities of Lyosecrteome, can be of interest for the prompt preparation of ready to use plasma derivatives (as for instance platelet rich and poor plasma gels) suitable for clinical applications in the field of regenerative medicine. Moreover these gels, applied at the site of injury, would allow the beneficial substances present within the Lyosecretoma to remain localized in situ and act directly on the damaged tissue
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
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