460 research outputs found

    The antiquarian photography of Cosmo Innes

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    The article focuses on the photography of historian Cosmo Innes. The author provides a brief historical background on Innes, discusses his interest in photographing pre-Reformation Scottish churches, and contrasts his work depicting church architecture to his photographs of country mansions, including Cawdor Castle, Auldbar Castle, and Gordon Castle

    Innes Smith Medical Portrait

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    Portrait of Sir Thomas Browne. Physician and author. After a paintin

    Innes Smith Medical Portrait

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    Photograph of a sculpture of John Heysham. Author of "The Carlisle Bills of Mortality

    Innes Smith Medical Portrait

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    Portrait of David Macbeth Moir. Physician and author at Musselburg. After a painting by Sir John Watson Gordo

    Empty Boots - A Whaling Story: Alan Innes-Taylor

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    The following is a heretofore unpublished account of a small but significant part of the 1st Byrd Antarctic Expedition, 1928-1930. It recounts one man\u27s first journey to Antarctica. The author is the late Alan Innes-Taylor, polar survival expert, and the manuscript was recently made available by his family. Only minor grammatical changes have been made. ... [The account describes his time aboard a whaling ship enroute to the Antarctic.

    DAG1 haploinsufficiency is associated with sporadic and familial isolated or pauci-symptomatic hyperCKemia

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    DAG1 encodes for dystroglycan, a key component of the dystrophin-glycoprotein complex (DGC) with a pivotal role in skeletal muscle function and maintenance. Biallelic loss-of-function DAG1 variants cause severe muscular dystrophy and muscle-eye-brain disease. A possible contribution of DAG1 deficiency to milder muscular phenotypes has been suggested. We investigated the genetic background of twelve subjects with persistent mild-to-severe hyperCKemia to dissect the role of DAG1 in this condition. Genetic testing was performed through exome sequencing (ES) or custom NGS panels including various genes involved in a spectrum of muscular disorders. Histopathological and Western blot analyses were performed on muscle biopsy samples obtained from three patients. We identified seven novel heterozygous truncating variants in DAG1 segregating with isolated or pauci-symptomatic hyperCKemia in all families. The variants were rare and predicted to lead to nonsense-mediated mRNA decay or the formation of a truncated transcript. In four cases, DAG1 variants were inherited from similarly affected parents. Histopathological analysis revealed a decreased expression of dystroglycan subunits and Western blot confirmed a significantly reduced expression of beta-dystroglycan in muscle samples. This study supports the pathogenic role of DAG1 haploinsufficiency in isolated or pauci-symptomatic hyperCKemia, with implications for clinical management and genetic counseling

    Facilitating independence: The benefits of a post-diagnostic support project for people with dementia.

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    Providing support in the form of information, advice and access to services or social events is promoted as beneficial for people newly diagnosed with dementia and their families. This paper reports on key findings from an evaluation of a post-diagnostic support pilot project in Scotland addressing local service gaps, namely information provision, emotional and practical support and maintaining community links. Twenty-seven participants (14 people newly diagnosed with dementia and 13 family carers) were interviewed at two time points: T1 shortly after joining the pilot project and T2 approximately six months later, to ascertain their views on existing services and the support offered by the pilot project. A comparative thematic analysis revealed that the project facilitated increased independence (associated with increased motivation and self-confidence) of people with dementia. The project illustrates what can be achieved if resources are targeted at providing individualised post-diagnostic support, particularly where there are service delivery gaps

    Photoacoustic Absorption Spectrum Of The 1436Cm11436 Cm^{-1} Band Of The 3B3u1Ag^{3}B_{3u}-1Ag System of s.Tetrazine.

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    1.^{1.} K.K. Innes, I.G. Ross \& W.R. Moomaw J. Mol. Spectrosc. 132, 492 (1988). 2.^{2.} R. Hochstrasser and D.S. King Chem. Phys. 5, 439 (1974). 3.^{3.} D.T. Livak and K.K. Innes J. Mol. Spectrosc. 39. 115 (1971).Author Institution: Department of Chemistry, S.U.N.Y. BinghamtonThe 3B3u1Ag(π)^{3}B_{3u}-1Ag (\pi) band system of s-tetrazine with its origin at 13608cm113608 cm^{-1} is known (1-3) to be dominated by a progression built on the 6a10 in-plane ring breathing vibrational mode. A high resolution room temperature vapor phase intracavity absorption spectrum of the 6a026a^{2}_{0} band of s-tetrazine was recorded using photoacoustic detection. The band origin is located at 15043.8cm115043.8 cm^{-1} and the band is violet degraded. The sharp and extensive rovibronic features of this band are subjected to rotational analyses, the results of which will be presented along with a few interesting dynamic properties of the spin sublevels of this triplet state

    Final : Oregon efficiency study final report

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    submitted to: Office of Student Learning and Partnerships, Oregon Department of Education ; prepared by: American Institutes for Research, Thomas B. Parrish, Ed.D., Fiona K. Innes Helsel, Ph.D., Jenifer J. Harr, Ph.D.Title from PDF cover (viewed on September 27, 2023).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
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