454 research outputs found
Combustion and Society: A Fire-Centred History of Energy Use
Get PDFFire is a force that links everyday human activities to some of the most powerful energetic movements of the Earth. Drawing together the energy-centred social theory of Georges Bataille, the fire-centred environmental history of Stephen Pyne, and the work of a number of ‘pyrotechnology’ scholars, the paper proposes that the generalized study of combustion is a key to contextualizing human energetic practices within a broader ‘economy’ of terrestrial and cosmic energy flows. We examine the relatively recent turn towards fossil-fuelled ‘internal combustion’ in the light of a much longer human history of ‘broadcast’ burning of vegetation and of artisanal pyrotechnologies – the use of heat to transform diverse materials. A combustion-centred analysis, it is argued, brings human collective life into closer contact with the geochemical and geologic conditions of earthly existence, while also pointing to the significance of explorative, experimental and even playful dispositions towards energy and matter. © 2014, SAGE Publications. All rights reserved
East of the Wind and West of the Rain
Get PDFabstract: There are places that rest tangibly on the Earth's surface, and places that flourish only in the imagination, and places that site their existence within a moral geography, and a few places, not many, Bor Island among them, that manage to fuse all these settings together. In truth, Bor belongs with that long tradition of island Arcadias that have attracted Western thinkers since well before Thomas More in 1516 gave them the name they now have: Utopia. What makes Bor Island unique is that its informing theme is fire.This is a pre-copy-editing, author-produced PDF of an article accepted for publication in ISLE-INTERDISCIPLINARY STUDIES IN LITERATURE AND ENVIRONMENT following peer review. The definitive publisher-authenticated version & Pyne, Stephen J. (2015). East of the Wind and West of the Rain. ISLE-INTERDISCIPLINARY STUDIES IN LITERATURE AND ENVIRONMENT, 22(1), 155-163. http://dx.doi.org/10.1093/isle/isv001 is available online at: http://dx.doi.org/10.1093/isle/isv00
Mechanotransduction pathways promoting tumor progression are activated in invasive human squamous cell carcinoma
No full textCutaneous squamous cell carcinomas (SCCs) are commonly diagnosed skin cancers that may progress to invasiveness in the absence of early intervention. Using a murine model of SCC, we have previously demonstrated that activation of the Rho-associated kinase (ROCK) signaling pathway promotes rapid progression of pre-neoplastic lesions to invasive SCC. Herein we demonstrate that in human cutaneous SCC, ROCK signaling is increasingly up-regulated with tumor progression in both tumor cells and cells of the tumor microenvironment and is accompanied by key tumor-promoting changes in the extracellular matrix protein composition. The mechanotransduction pathway mediated by integrin signaling through FAK, GSK3β, and the transcription coactivator β-catenin is also progressively activated in human cutaneous SCC. Our observations indicate that ROCK activation is a tumor promoter in human cutaneous SCC and acts via mechanotransduction of signals to β-catenin. Our experiments raise the possibility that inhibition of ROCK signaling could be a useful therapeutic approach to halt cutaneous SCC progression by reducing the signal flux through this pathway to physiologic levels, thereby normalizing the extracellular matrix composition.S. Jan Ibbetson, Natasha T. Pyne, Anthony N. Pollard, Michael F. Olson, and Michael S. Samue
The power of love [music] : ballad /
No full text"Sung by Miss Louisa Pyne in the romantic opera Satanella, or The Power of love.; Also available online http://nla.gov.au/nla.mus-an6573166; MUS: N, Snell.Satanella. Power of lov
Massachusetts Archives Collection. v.165-Revolution Council Papers, 1776. SC1/series 45X, Petition of Richard Pyne
No full textPetition subject: Permission to travel Original: http://nrs.harvard.edu/urn-3:FHCL:13909078 Date of creation: 1776 Selected signatures:Richard Pyne Actions taken on dates: 1776-09-27 Legislative action: Received in the Council on September 27, 1776 and read and ordered and granted Total signatures: 1 Legislative action summary: Received, read, ordered, granted Legal voter signatures (males not identified as non-legal): 1 Female only signatures: No Prayer format was printed vs. manuscript: Manuscript Additional archivist notes: Lettis and Hay of the island of St. Michael's, Saint Michael, St. Michael, Barbados, "design to carry slaves," slave trade, West Indies, schooner Hancock, Lynn, ship William, Benjamin Moore, William Ross, Great Britain, England, Nathaniel Morgan, [also see pages 295-295a] Location of the petition at the Massachusetts Archives of the Commonwealth: Massachusetts Archives volume 165, pages 293-294 Acknowledgements: Supported by the National Endowment for the Humanities (PW-5105612), Massachusetts Archives of the Commonwealth, Radcliffe Institute for Advanced Study at Harvard University, Center for American Political Studies at Harvard University, Institutional Development Initiative at Harvard University, and Harvard University Library.</p
Massachusetts Archives Collection. v.165-Revolution Council Papers, 1776. SC1/series 45X, Petition of Richard Pyne
No full textPetition subject: Permission to travel Original: http://nrs.harvard.edu/urn-3:FHCL:13909078 Date of creation: 17760000 Selected signatures:Richard Pyne Actions taken on dates: 1776-09-27 Legislative action: Received in the Council on September 27, 1776 and read and ordered and permitted Total signatures: 1 Legislative action summary: Received, read, ordered, permitted Legal voter signatures (males not identified as non-legal): 1 Female only signatures: No Prayer format was printed vs. manuscript: Manuscript Additional archivist notes: Lettis and Hay of the island of St. Michael's, Saint Michael, St. Michael, Barbados, "design to carry slaves," slave trade, West Indies, schooner Hancock, Lynn, ship William, Benjamin Moore, William Ross, Great Britain, England, Nathaniel Morgan, [also see pages 295-295a] Location of the petition at the Massachusetts Archives of the Commonwealth: Massachusetts Archives volume 165, pages 293-294 Acknowledgements: Supported by the National Endowment for the Humanities (PW-5105612), Massachusetts Archives of the Commonwealth, Radcliffe Institute for Advanced Study at Harvard University, Center for American Political Studies at Harvard University, Institutional Development Initiative at Harvard University, and Harvard University Library.</p
Massachusetts Archives Collection. v.165-Revolution Council Papers, 1776. SC1/series 45X, Petition of Richard Pyne
No full textPetition subject: Permission to travel Original: http://nrs.harvard.edu/urn-3:FHCL:13909078 Date of creation: 17760000 Selected signatures:Richard Pyne Actions taken on dates: 1776-09-27 Legislative action: Received in the Council on September 27, 1776 and read and ordered and permitted Total signatures: 1 Legislative action summary: Received, read, ordered, permitted Legal voter signatures (males not identified as non-legal): 1 Female only signatures: No Prayer format was printed vs. manuscript: Manuscript Additional archivist notes: Lettis and Hay of the island of St. Michael's, Saint Michael, St. Michael, Barbados, "design to carry slaves," slave trade, West Indies, schooner Hancock, Lynn, ship William, Benjamin Moore, William Ross, Great Britain, England, Nathaniel Morgan, [also see pages 295-295a] Location of the petition at the Massachusetts Archives of the Commonwealth: Massachusetts Archives volume 165, pages 293-294 Acknowledgements: Supported by the National Endowment for the Humanities (PW-5105612), Massachusetts Archives of the Commonwealth, Radcliffe Institute for Advanced Study at Harvard University, Center for American Political Studies at Harvard University, Institutional Development Initiative at Harvard University, and Harvard University Library.</p
The power of love [music] : from Satanella /
No full text"Sung by Miss Louisa Pyne".; "Dedicated to the Marchioness of Downshire".; Also available online http://nla.gov.au/nla.mus-vn4282230.Satanella. The power of love. Piano ; arranged
Preparing a High-Quality and Impactful Sport Science Manuscript
No full textResearch impact can be defined in the context of sports performance and physiology as the contribution to both the research/academic (knowledge discovery) and sporting (real-world application) communities. Practical application has always been a hallmark of the International Journal of Sports Physiology and Performance (IJSPP), with articles that clearly identify how and why study outcomes can be implemented in training and competition to enhance performance. Some outcomes apply to a broad range of sports, while others are more specific to a sporting discipline, such as aquatic sports, court or field sports, individual time-based sports, or otherwise just meet the requirements of a single sport, discipline, or event. Strengthening the practice and reporting of sport and exercise science research is the responsibility of every author.1 Three key areas in ensuring a high-quality manuscript are project formulation and design; methodology and analytical issues; and style, clarity, and quality of the written presentation
Identity and dislocation in Caribbean women's literature: a study of the writings of Velma Pollard
No full textJamaican-born Velma Pollard has been publishing poetry and short stories for nearly
thirty years. Her first poems appeared in the 1970s, her first volume of short stories in
1989, and her first novel in 1994. Despite this considerable literary output, in the evergrowing
critical literature on Caribbean women's writing Pollard's work has not attracted
any of the scholarly treatment accorded to other writers. Given this lack of critical
attention to Pollard's considerable body of work, this thesis aims to provide the first
detailed and contextualised study of her writings (excluding the majority of her poetry
and of her writings on linguistics), and to accord Pollard the recognition her work
deserves.
Chapter 1 of this thesis situates Pollard's writings in the context of Caribbean
(women's) literature, and writings on identity, dislocations and (Caribbean) migration. I
argue that Pollard's principal contribution to Caribbean literature is found in her
engagement with two main subjects, return migration and relationships (male-female and
female-female), within a wider context of debates on identity and dislocation.
Chapter 2 introduces Pollard's work by way of a general discussion of her novella
Karl, which won the Casa de las Americas literary award in 1992. I consider Karl to be
central to Pollard's work, not least because it features many of the themes explored by
her later writings, including her novel, Homestretch, which is the subject of Chapter 3.
Pollard's first novel, Homestretch, which was published in 1994, explores the themes
of identity and dislocation through the experiences of 'return migrants' and 'repeat
migrants' and their comparison of life in England, the United States and Jamaica. The
novel chronicles how these migrants come to reconnect with and accept their cultural
heritage.
In chapters 4 and 5 I discuss selected stories taken from Pollard's two collections
of short stories, Considering Woman ('Cages', 'My Sisters', 'My Mother', and 'Gran') and
from Karl and Other Stories ('A Night's Tale', 'Miss Chandra', 'Betsy Hyde', and 'Altamont
Jones'). In these stories Pollard explores male-female relationships and the lives of
several generations and a wide range of Caribbean women and men. Pollard utilises the
West Indian setting, speech, situations and conflicts in these stories to graphically
describe familiar Caribbean role models and to provide a narrative and literary
examination of the frustrations and conflicting desires of women in the region.
In my conclusion, I address the ethnographic quality and significance of her work,
and its contribution to an understanding of the Caribbean
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