446 research outputs found
Expression of mgtA encoding a magnesium transporter is activated in the absence of the main Mg2+ transporter CorA in Salmonella
No full textSalmonella imports magnesium via three known transporters, the widely conserved CorA transporter and the MgtA and MgtB P-type ATPases. CorA is expressed under various growth conditions whereas the other two magnesium transporters, MgtA and MgtB, are expressed under conditions of magnesium starvation under the positive control of the PhoP-PhoQ regulatory system.
Our recent results suggest that production of MgtA, but not that of MgtB, is activated in the absence of the main Mg2+ transporter CorA (Metaane et al 2022, 2023 )
This hypothesis was further validated in this study by using transcriptional and translational lacZ fusions in the mgtA and mgtB genes. In addition, our data suggest that regulation of expression of MgtA in the absence of CorA is post-transcriptional .
Metaane S, Monteil V, Ayrault S, Bordier L, Levi-Meyreuis C, Norel F. The stress sigma factor sigmaS/RpoS counteracts Fur repression of genes involved in iron and manganese metabolism and modulates the ionome of Salmonella enterica serovar Typhimurium. PLoS One. 2022;17(3):e0265511.
Metaane S, Monteil V, Douché T, Giai Gianetto Q, Matondo M, Maufrais C, Norel F. Loss of CorA, the primary magnesium transporter of Salmonella, is alleviated by MgtA and PhoP-dependent compensatory mechanisms. PLoS One. 2023; manuscript under revision
Expression of a corA-lacZ transcriptional fusion in Salmonella
No full textA corA-lacZ transcriptional fusion was shown to be activated by RpoS when Salmonella is grown to stationary phase in LB rich medium (Metaane et al. 2022, PLoS ONE 17(3): e0265511)
Here, expression of the corA-lacZ fusion was evaluated in Salmonella wild-type strain and rpoS mutant grown to stationary phase in LB medium containing different concentrations of Mg and in minimal medium M63 starved or not for Mg. RpoS was required fort optimal expression of the fusion in these three environmental conditions and level of expression was slightly higher when the extracellular magnesium concentration was low
"Selma" : "Selma"
No full textAbstract The author Selma Lagerlöf was born in 1858 at Mårbacka, in Värmland and died in 1940. Fifty years after Selma´s death were her correspondence released and ten thousand of letters were found in the collection. But it was just the correspondence between Selma and Sofie Elkan who interested people because they wanted to know if Selma and Sofie have had a sexual relationship. Later, in time for Christmas 2008 the Swedish Television shows a film about Selma. "Selma Lagerlöf Society" was critical to the movie and thougt that the movie focused too much on Selma`s sexual orientation. This situation aroused a curiosity and a desire to find out why the film was perceived in this way. The purpose of this work is to show how the producer uses gender constructions to show that Selma was a lesbian and for that reason a thematic analysis was made from a social constructionist perspective. Different themes about gender constructions emerge in the analysis, and those themes are presented together with feminist theorist as Judith Butler, Yvonne Hirdman and Simone De Beauvoir. The discussion is about the presentation and how this can be perceived, but also about the reasons they might have had in mind when they made the presentation that way.Författarinnan Selma Lagerlöf föddes 20 november 1858, på Mårbacka i Värmland, och dog 16 mars 1940. Femtio år senare släpptes Selmas korrespondens fri. Tiotusentals brev fanns i denna brevsamling men det var endast brevväxlingen mellan Selma och Sofie Elkan som ansågs intressant. Detta på grund av att man ville veta om Selma och Sofie hade en sexuell relation eller inte. Senare lagom till julhelgen 2008 visar Sveriges Television en film i två delar, som handlar om Selma. Bland annat Selma Lagerlöf sällskapet ställde sig kritisk till filmen och menade att man fokuserat för mycket på Selmas sexualitet i filmen. Detta väckte en nyfikenhet och en önskan hos mig, att ta reda på varför filmen uppfattades på detta sätt. Syftet med detta arbete är att visa på hur man i framställningen har använt sig av könskonstruktioner för att visa att Selma var lesbisk Av denna anledning har det gjorts en tematisk analys ur ett socialkonstruktivistiskt perspektiv med utgångspunkt i filmens innehåll . Under analys har olika teman framträtt som på något sätt handlar om könskonstruktioner. Dessa teman presenteras i analysdelen tillsammans med feministisk teorier av bland annat Judith Butler, Yvonne Hirdman och Simone De Beauvoir. I diskussionen behandlas det hur framställningen kan uppfattas och även vilka motiv man kan tänkas ha haft i åtanke när man gjort framställningen på detta sätt
Selma Lagerlöf och Sophie Elkan
No full textA description of the friendship between the Swedish children's books author Selma Lagerlöf and the Jewish-Swedish author Sophie Elkan
Correction to: TOPOLOGICAL STRUCTURE OF SOLUTION SET FOR ψ-HILFER FRACTIONAL DIFFERENTIAL EQUATIONS IN BANACH SPACE (Journal of Mathematical Sciences, (2024), 10.1007/s10958-024-07399-0)
No full textThe published version of this article unfortunately contained a mistake. The author name Selma Gülyaz‑Öztürk should be Selma Gülyaz-Özyurt. The original article has been corrected. © 2025 The Author(s), under exclusive licence to Springer Nature Switzerland AG
Bactéries persistantes : vers un nouvel angle d’attaque dans la thérapeutique antimicrobienne ?
No full textThe term of "persisters" has been used for the first time in the early 1940s to qualify sub-populations of bacterial phenotypic variants that are able to survive to many stresses such as antibiotics, oxidative stress or a sudden variation of pH or temperature. With the notion of persisters, appeared the idea that most of the antibotics are not efficient to sterilize completely a bacterial culture. That’s why many therapeutic strategies arose to find a way to fully eradicate these bacterial persisters cells.Le terme « persisters » a été utilisé pour la première fois dans les années 1940 pour qualifier des sous-populations bactériennes de variants phénotypiques capables de survivre à divers chocs tels que des antibiotiques, un stress oxydant ou une variation brutale de pH ou de température. Avec la notion de persisters est apparue l’idée selon laquelle la plupart des antibiotiques ne permettaient pas de stériliser totalement une culture bactérienne, et de ce fait, des stratégies thérapeutiques ont émergé afin d’éradiquer totalement ces persisters
Membrane remodeling and ion homeostasis in non-actively growing Salmonella
No full textUne stratégie utilisée par de nombreuses bactéries pour survivre en conditions de stress ou en présence d'antibiotiques consiste à entrer en quiescence. Cet arrêt temporaire de croissance leur permet de résister à de nombreux stress et à persister dans des environnements défavorables. Cet état de multi-résistance a un impact environnemental et médical et il est crucial d'en comprendre les déterminants moléculaires et physiologiques. En utilisant des approches globales et analytiques chez le pathogène humain Salmonella, nous étudions un nouvel aspect de ce remodelage, le contrôle de l'homéostasie de certains ions métalliques.One strategy used by many bacteria to survive under stressful conditions or in the presence of antibiotics is to enter in a quiescent state. This temporary arrest of growth allows them to resist many stresses and to persist in adverse environments. This state of multi-resistance has an environmental and medical impact and it is crucial to understand its molecular and physiological determinants. Using global and analytical approaches in the human pathogen Salmonella, we study a new aspect of this remodeling, the control of the homeostasis of certain metal ions
Los avatares del yo: iteratura Argentina en primera persona a partir de 1990
No full textI examine a corpus of narrative texts (nouvelle, short story, and essay) and poems that focuses on the relationship between the narrative/poetic “I” and referentiality to account for new ontological dimensions of the first person in Argentine literature since 1990. Acknowledging the rich Argentinean autobiographical tradition from Domingo F. Sarmiento to Jorge Luis Borges, I argue that the works in my corpus present a shift from self-conscious and metafictional positions regarding the first person. I analyze a variety of uses of the “I” related to auto-fiction, the pseudonym, the “performance of the author” and the biography of the voice traced in the texts as representational strategies that address the fluid borders of the “I” in contemporary writing. My analysis takes into account works by Alan Pauls, Washington Cucurto, Silvio Mattoni and Matilde Sánchez. Based upon the theories of Philippe Lejeune, Régine Robin, Serge Doubrovsky, and Sylvia Molloy regarding the definitions of auto-fiction and autobiography, I identify the emergence of new meanings and functions for the concept of intimacy and strategies of self-representation. These changes in subjectivity and writing in the first person are strongly marked by postmodernism and globalization. Following the considerations of Néstor García Canclini and Arjun Appadurai on globalization and new media, I argue that in contemporary times there are new parameters of production of space and time that have a strong impact on the subject configuration and its ways of relating to the world where experience plays a key role in new articulations of the “I”. In my corpus I also analyze the gradual but persistent genre hybridization of texts that also engage with the visual. The texts I study increasingly refer to and incorporate images such as photographs, drawings, and comics. Politics and collective imagination are other aspects of literature in the first person. All the works I analyze transcend the individual to relate to others. Some of them make specific comments on politics or promote the development of community projects, such as the cooperative Eloísa Cartonera. Others address gender issues and their relationship with the male literary tradition. From different perspectives and approaches all of them take part in the interplay and discussion of the contemporary Argentinean cultural field.Ph. D.Includes bibliographical referencesby Selma Cohe
The artistic method of Selma Lagerlöf, a study of form and idea in Körkarlen
No full textThe essay deals with the patterns of storytelling in Selma Lagerlöfs novel "Körkarlen". The focus is on the relationship between idea and form. Selma Lagerlöf tries to show how the drinker David Holm comes to insight about his own shortcomings and faults without knowing that he is in fact educated by his old friend. The author of this essay tries to show that Selma Lagerlöf use the same method in relation to the reader of the novel. Selma Lagerlöf wants to enlighten the reader without actually preaching. To som extent the essay deals with typical patterns of storytelling that Selma Lagerlöf uses, such as her symbolic method, her use of patterns from legends and ghost stories and finally her esthetics.Uppsatsen berör Selma Lagerlöfs sätt att gestalta ett relativt kontroversiellt idéinnehåll. Selma Lagerlöf går delvis i dialog med läsaren och antyder hur skeendet i Körkarlen kan tolkas, samtidigt som hon lämnar utrymme för läsarens egna reaktioner. En stor del av uppsatsen berör typiska mönster för Selma Lagerlöfs berättarteknik, såsom användandet av sagans, legendens och spåkhistoriens mönster, symboltekniken samt hennes estetiska hållning. I Körkarlen är det Selma Lagerlöfs intention att drinkaren David Holm skall komma till insikt genom vägledning utan att han själv är medveten om att han undervisas. Uppsatsens författare driver tesen att Lagerlöf intar samma hållning gentemot läsaren
Health and demographic characteristics of twin births, United States, 1988
No full textAuthor: Selma M. Taffel."National trends in twin birth incidence by race of child are analyzed for the period 1950-88. Also reviewed are maternal and infant health and demographic characteristics associated with twin delivery for the year 1988."Includes bibliographical references.199213911271116
- …
