51 research outputs found
Note del terapeuta e misure del processo referenziale. Un possibile "terzo analitico"
No full textViene proposta un’analisi delle note riportate dal terapeuta sul lavoro clinico con un paziente, condotta attraverso l’applicazione delle misure linguistiche computerizzate elaborate all’interno della teoria del codice multiplo. I risultati, in accordo con la letteratura, hanno evidenziato una forte relazione tra le qualità linguistiche degli appunti del terapeuta e l’efficacia del lavoro clinico. L’analisi linguistica delle note del terapeuta può quindi, oltre ad ampliare le possibilità della ricerca clinica, essere un utile supporto per comprendere e prevedere in una certa misura l’andamento del caso e il tipo di relazione che si instaura nella coppia durante il lavoro terapeutico. Il clinico che adotta questa metodologia nella propria prassi professionale può disporre di uno strumento di analisi che facilita la supervisione e la riflessione sul caso, divenendo così un “terzo analitico” che contribuisce a monitorare e potenziare il processo referenziale che lo connette con l’esperienza emozionale che sta vivendo e con il paziente.The Author presents an analysis of a therapist’s notes on the clinical work with a patient by means of Multiple Code Theory computerized linguistic measures. In accordance with literature the results show a strong connection between the linguistic properties of the therapist’s notes and the effectiveness of treatment. Thus, the linguistic analysis of the therapist’s notes not only expands the possibilities of clinical research, but also could be a useful support to understand and predict the evolution of a case and the type of relationship developed by the therapeutic couple. Clinicians that adopt this methodology in their professional practice have a useful tool facilitating supervision and reflection on the case. This tool can be considered as an “analytic third” monitoring and strengthening the referential process that connects therapists to their lived emotional experience and to patients
Corrigendum: The Italian Mastocytosis Registry: 6-year experience from a hospital-based registry (Future Oncology (2018) 14:26 (2713-2723) DOI: 10.2217/fon-2018-0291)
No full textFollowing publication of the Research Article by SerenaMerante, Virginia V Ferretti, Chiara Elena, Valeria Brazzelli, Roberta Zanotti, Iria Neri, DiomiraMaglicane, Anna Belloni Fortina, Forer Ingeborg, Elide A Pastorello, Lisa Pieri, Cristina Papayannidis, Marina Mauro, Federica Grifoni, Roberto Minelli, Elena Guggiari, Elisa Difonzo, Monica Bocchia, Francesca Caroppo, Sergio DiNuzzo, ElenaMaria Elli,Michaela Rondoni, Rachele Ciccocioppo,Michele Di Stefano, Grazia Bossi, Emanuela Boveri, Patrizia Bonadonna, Fiorina Giona, Peter Valent &Massimo Triggiani, titled 'The Italian Mastocytosis Registry: 6-year experience from a hospital-based registry', which appeared in the November 2018 issue of Future Oncology (Future Oncology [Lond.] 14[26], 2713-2723 [2018]; DOI: 10.2217/fon-2018-0291), it has been brought to our attention that the name of Iria Neri has been corrected as follows: The author name was originally published as Iria Ner, and has been corrected to Iria Neri. The authors and editors of Future Oncology would like to sincerely apologise for any confusion or inconvenience this may have caused our readers
A case of extremely prolonged viral shedding: Could cell cultures be a diagnostic tool to drive COVID-19 patient discharge?
No full textThis study addressed the case of a patient with prolonged COVID-19 viral shedding, reported by Real Time PCR, until 71 days from symptom onset. However, viral culture received negative results after 30 days from symptom onset. Therefore, viral culture may be a worthwhile test for patients requiring discharge, in particular for those presenting prolonged viral shedding. ? 2020 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-ncnd/4.0/)
Translating Racial Slurs: A Comparative Analysis of Gran Torino Assessing Transfer of Offensive Language between English and Italian.
No full textThis dissertation focuses on the role played by translations in constructing a cultural product. It chooses the American film 'Gran Torino' (2008) as its source text and discusses the ideological and cultural implications of rendering racial slurs from English into Italian. The dissertation therefore sets the analysis against a backdrop of contemporary North American and European culture understood in linguistic and behavioural patterns and questions the role of audiovisual translational norms in the source culture and tasks of translators in general when dealing with such highly sensitive, culture-bound issues pertaining to the meaning transfer of lingua-cultural taboos. The comparative analysis of the audiovisual texts takes a Critical Discourse perspective, with a strong ideological focus on the possible translation effects
Multimorbidity and polypharmacy in the elderly: Lessons from REPOSI
No full textThe dramatic demographic changes that are occurring in the third millennium are modifying the mission of generalist professionals such as primary care physicians and internists. Multiple chronic diseases and the related prescription of multiple medications are becoming typical problems and present many challenges. Unfortunately, the available evidence regarding the efficacy of medications has been generated by clinical trials involving patients completely different from those currently admitted to internal medicine: much younger, affected by a single disease and managed in a highly controlled research environment. Because only registries can provide information on drug effectiveness in real-life conditions, REPOSI started in 2008 with the goal of acquiring data on elderly people acutely admitted to medical or geriatric hospital wards in Italy. The main goals of the registry were to evaluate drug prescription appropriateness, the relationship between multimorbidity/polypharmacy and such cogent outcomes as hospital mortality and re-hospitalization, and the identification of disease clusters that most often concomitantly occur in the elderly. The findings of 3-yearly REPOSI runs (2008, 2010, 2012) suggest the following pertinent tasks for the internist in order to optimally handle their elderly patients: the management of multiple medications, the need to become acquainted with geriatric multidimensional tools, the promotion and implementation of a multidisciplinary team approach to patient health and care and the corresponding involvement of patients and their relatives and caregivers. There is also a need for more research, tailored to the peculiar features of the multimorbid elderly patient
Correction to: Solving patients with rare diseases through programmatic reanalysis of genome-phenome data
No full textIn the original publication of the article, consortium author lists were missing in the articl
Defining Aging Phenotypes and Related Outcomes: Clues to Recognize Frailty in Hospitalized Older Patients
No full textBackground: Because frailty is a complex phenomenon associated with poor outcomes, the identification of patient profiles with different care needs might be of greater practical help than to look for a unifying definition. This study aimed at identifying aging phenotypes and their related outcomes in order to recognize frailty in hospitalized older patients. Methods: Patients aged 65 or older enrolled in internal medicine and geriatric wards participating in the REPOSI registry. Relationships among variables associated to sociodemographic, physical, cognitive, functional, and medical status were explored using a multiple correspondence analysis. The hierarchical cluster analysis was then performed to identify possible patient profiles. Multivariable logistic regression was used to verify the association between clusters and outcomes (in-hospital mortality and 3-month postdischarge mortality and rehospitalization). Results: 2,841 patients were included in the statistical analyses. Four clusters were identified: the healthiest (I); those with multimorbidity (II); the functionally independent women with osteoporosis and arthritis (III); and the functionally dependent oldest old patients with cognitive impairment (IV). There was a significantly higher in-hospital mortality in Cluster II (odds ratio [OR] = 2.27, 95% confidence interval [CI] = 1.15-4.46) and Cluster IV (OR = 5.15, 95% CI = 2.58-10.26) and a higher 3-month mortality in Cluster II (OR = 1.66, 95% CI = 1.13-2.44) and Cluster IV (OR = 1.86, 95% CI = 1.15-3.00) than in Cluster I. Conclusions: Using alternative analytical techniques among hospitalized older patients, we could distinguish different frailty phenotypes, differently associated with adverse events. The identification of different patient profiles can help defining the best care strategy according to specific patient needs. © The Author 2016. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved
Correction: Solving unsolved rare neurological diseases—a Solve-RD viewpoint
No full textIn the original publication of the article, consortium author lists were missing in the article
Correction to: Solve-RD: systematic pan-European data sharing and collaborative analysis to solve rare diseases
No full textIn the original publication of the article, consortium author list was missing in the article
Estimated pulse wave velocity improves risk stratification for all-cause mortality in patients with COVID-19
No full text\ua9 2021, The Author(s). Accurate risk stratification in COVID-19 patients consists a major clinical need to guide therapeutic strategies. We sought to evaluate the prognostic role of estimated pulse wave velocity (ePWV), a marker of arterial stiffness which reflects overall arterial integrity and aging, in risk stratification of hospitalized patients with COVID-19. This retrospective, longitudinal cohort study, analyzed a total population of 1671 subjects consisting of 737 hospitalized COVID-19 patients consecutively recruited from two tertiary centers (Newcastle cohort: n = 471 and Pisa cohort: n = 266) and a non-COVID control cohort (n = 934). Arterial stiffness was calculated using validated formulae for ePWV. ePWV progressively increased across the control group, COVID-19 survivors and deceased patients (adjusted mean increase per group 1.89 m/s, P < 0.001). Using a machine learning approach, ePWV provided incremental prognostic value and improved reclassification for mortality over the core model including age, sex and comorbidities [AUC (core model + ePWV vs. core model) = 0.864 vs. 0.755]. ePWV provided similar prognostic value when pulse pressure or hs-Troponin were added to the core model or over its components including age and mean blood pressure (p < 0.05 for all). The optimal prognostic ePWV value was 13.0 m/s. ePWV conferred additive discrimination (AUC: 0.817 versus 0.779, P < 0.001) and reclassification value (NRI = 0.381, P < 0.001) over the 4C Mortality score, a validated score for predicting mortality in COVID-19 and the Charlson comorbidity index. We suggest that calculation of ePWV, a readily applicable estimation of arterial stiffness, may serve as an additional clinical tool to refine risk stratification of hospitalized patients with COVID-19 beyond established risk factors and scores
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