1,721,111 research outputs found
Generalized diffraction enhanced imaging to retrieve absorption, refraction and scattering effects
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Three-image diffraction enhanced imaging algorithm to extract absorption, refraction, and ultrasmall-angle scattering
No full textAs different methods to improve diffraction enhanced imaging are proposed, the authors introduce a simple algorithm that follows the original idea of Chapman et al. (Phys. Med. Biol. 42, 2015, 1997), but extend it to a general object featuring absorption, refraction, and ultrasmall-angle scattering. The information relative to the three effects is decoupled, requiring only three images in input. Simulation and experiment give accurate results, provided the refraction and scattering angles are small compared to the rocking curve width. The proposed algorithm can be readily and fruitfully implemented in several applications, particularly when time and dose constraints are relevant
Spectral micro-CT for simultaneous gold and iodine detection, and multi-material identification
Full text linkMultiple energy bin spectral micro-CT (SμCT) is an advanced imaging technique that allows multi-material decomposition according to their specific absorption patterns at a sub-100 μm scale. Typically, iodine is the preferred CT contrast agent for cardiovascular imaging, while gold nanoparticles have gained attention in recent years owing to their high absorption properties, biocompatibility and ability to target tumors. In this work, we demonstrate the potential for multi-material decomposition through SμCT imaging of a test sample at the PEPI lab of INFN Trieste. The sample, consisting of gold, iodine, calcium, and water, was imaged using a Pixirad1/PixieIII chromatic detector with multiple energy thresholds and a wide spectrum (100 kV) produced by a micro-focus X-ray tube. The results demonstrate the simultaneous detection and separation of the four materials at a spatial scale of 35 μm, suggesting the potential of this technique in improving material detectability and quantification in a range of pre-clinical applications, including cardiovascular and oncologic imaging.
On the possibility of utilizing scattering-based contrast agents in combination with diffraction enhanced imaging
No full textGoing Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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