1,720,963 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Ethanol Modulates The Synthesis And Catabolism Of Retinoic Acid In The Rat Prostate
No full textAll-trans retinoic acid (atRA) maintains physiological stability of the prostate, and we reported that ethanol intake increases atRA in the rat prostate; however the mechanisms underlying these changes are unknown. We evaluated the impact of a low- and high-dose ethanol intake (UChA and UChB strains) on atRA metabolism in the dorsal and lateral prostate. Aldehyde dehydrogenase (ALDH) subtype 1A3 was increased in the dorsal prostate of UChA animals while ALDH1A1 and ALDH1A2 decreased in the lateral prostate. In UChB animals, ALDH1A1, ALDH1A2, and ALDH1A3 increased in the dorsal prostate, and ALDH1A3 decreased in the lateral prostate. atRA levels increased with the low activity of CYP2E1 and decreased with high CYP26 activity in the UChB dorsal prostate. Conversely, atRA was found to decrease when the activity of total CYP was increased in the UChA lateral prostate. Ethanol modulates the synthesis and catabolism of atRA in the prostate in a concentration-dependent manner.5319Fields, A.L., Soprano, D.R., Soprano, K.J., Retinoids in biological control and cancer (2007) J Cell Biochem, 102, pp. 886-898Altucci, L., Leibowitz, M.D., Ogilvie, K.M., de Lera, A.R., Gronemeyer, H., RAR and RXR modulation in cancer and metabolic disease (2007) Nat Rev Drug Discov, 6, pp. 793-810Kane, M.A., Folias, A.E., Wang, C., Napoli, J.L., Ethanol elevates physiological all-trans retinoic acid levels in select loci through altering retinoid metabolism in multiple loci: a potential mechanism of ethanol toxicity (2010) FASEB J, 24, pp. 823-832Lasnitzki, I., Goodman, D.S., Inhibition of the effects of methylcholanthrene on mouse prostate in organ culture by vitamin A and its analogs (1974) Cancer Res, 34, pp. 1564-1571Vezina, C.M., Allgeier, S.H., Fritz, W.A., Moore, R.W., Strerath, M., Bushman, W., Retinoic acid induces prostatic bud formation (2008) Dev Dyn, 237, pp. 1321-1333Pöschl, G., Seitz, H.K., Alcohol and cancer (2004) Alcohol Alcohol, 39, pp. 155-165Alizadeh, F., Bolhassani, A., Khavari, A., Bathaie, S.Z., Naji, T., Bidgoli, S.A., Retinoids and their biological effects against cancer (2014) Int Immunopharmacol, 18, pp. 43-49Kumar, S., Sandell, L.L., Trainor, P.A., Koentgen, F., Duester, G., Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout models (2011) Biochim Biophys Acta, 1821, pp. 198-205Molotkov, A., Duester, G., Retinol/ethanol drug interaction during acute alcohol intoxicationin mice involves inhibition of retinol metabolism to retinoic acidby alcohol dehydrogenase (2002) J Biol Chem, 277, pp. 22553-22557Lee, M.O., Manthey, C.L., Sladek, N.E., Identification of mouse liver aldehyde dehydrogenases that catalyze the oxidation of retinaldehyde to retinoic acid (1991) Biochem Pharmacol, 42, pp. 1279-1285Vasiliou, V., Pappa, A., Estey, T., Role of human aldehyde dehydrogenases in endobiotic and xenobiotic metabolism (2004) Drug Metab Rev, 36, pp. 279-299Ross, A.C., Zolfaghari, R., Cytochrome P450s in the regulation of cellular retinoic acid metabolism (2011) Annu Rev Nutr, 31, pp. 65-87Chithalen, J.V., Luu, L., Petkovich, M., Jones, G., HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A (2002) J Lipid Res, 43, pp. 1133-1142Taimi, M., Helvig, C., Wisniewski, J., Ramshaw, H., White, J., Amad, M., A novel human cytochrome P450, CYP26C1, involved in metabolism of 9-cis and all-trans isomers of retinoic acid (2004) J Biol Chem, 279, pp. 77-85Chung, J., Veeramachaneni, S., Liu, C., Mernitz, H., Russell, R.M., Wang, X.D., Vitamin E supplementation does not prevent ethanol-reduced hepatic retinoic acid levels in rats (2009) Nutr Res, 29, pp. 664-670Liu, C., Russell, R.M., Seitz, H.K., Wang, X.D., Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P450 2E1 (2001) Gastroenterology, 120, pp. 179-189Lieber, C.S., De Carli, L.M., Hepatotoxicity of ethanol (1991) J Hepathol, 12, pp. 394-401Wang, X.D., Chronic alcohol intake interferes with retinoid metabolism and signaling (1999) Nutr Rev, 57, pp. 51-59Chung, J., Liu, C., Smith, D.E., Seitz, H.K., Russell, R.M., Wang, X.D., Restoration of retinoic acid concentration supressesethanolenhanced c-Jun expression and hepatocyte proliferation in rat liver (2001) Carcinogenesis, 22, pp. 1213-1219Fontanelli, B.A.F., Chuffa, L.G.A., Teixeira, G.R., Amorim, J.P.A., Mendes, L.O., Pinheiro, P.F.F., Chronic ethanol consumption alters all-trans-retinoic acid concentration and expression of their receptors on the prostate: a possible link between alcoholism and prostate damage (2013) Alcohol Clin Exp Res, 37, pp. 49-56Pasquali, D., Thaller, C., Eichele, G., Abnormal level of retinoic acid in prostate cancer tissues (1996) J Clin Endocrinol Metab, 81, pp. 2186-2191Richter, F., Joyce, A., Fromowitz, F., Wang, S., Watson, J., Watson, R., Immunohistochemical localization of the retinoic acid receptors in human prostate (2002) J Androl, 23, pp. 830-838Mardones, J., Segovia-Riquelmi, N., Thirty-two years of rats by ethanol preference: UChA and UChB strains (1983) Neuro Behav Toxicol Teratol, 5, pp. 171-178Quintanilla, M.E., Israel, Y., Sapag, A., Tampier, L., The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake (2006) Addict Biol, 11, pp. 310-323Chuffa, L.G., Fioruci-Fontanelli, B.A., Mendes, L.O., Fávaro, W.J., Pinheiro, P.F., Martinez, M., Characterization of chemically induced ovarian carcinomas in an ethanol-preferring rat model: influence of long-term melatonin treatment (2013) PLoS One, 8, p. e81676Chuffa, L.G., Seiva, F.R., Fávaro, W.J., Amorim, J.P., Teixeira, G.R., Mendes, L.O., Melatonin and ethanol intake exert opposite effects on circulating estradiol and progesterone and differentially regulate sex steroid receptors in the ovaries, oviducts, and uteri of adult rats (2013) Reprod Toxicol, 39, pp. 40-49Chuffa, L.G., Amorim, J.P., Teixeira, G.R., Mendes, L.O., Fioruci, B.A., Pinheiro, P.F., Long-term exogenous melatonin treatment modulates overall feed efficiency and protects ovarian tissue against injuries caused by ethanol-induced oxidative stress in adult UChB rats (2011) Alcohol Clin Exp Res, 35, pp. 1498-1508Chuffa, L.G., Seiva, F.R., Fávaro, W.J., Teixeira, G.R., Amorim, J.P., Mendes, L.O., Melatonin reduces LH, 17 beta-estradiol and induces differential regulation of sex steroid receptors in reproductive tissues during rat ovulation (2011) Reprod Biol Endocrinol, 9, p. 108Guo, X., Knudsen, B.S., Peehl, D.M., Ruiz, A., Bok, D., Rando, R.R., Retinol metabolism and lecithin: retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens (2002) Cancer Res, 62, pp. 1654-1661Kim, H., Lapointe, J., Kaygusuz, G., Ong, D., Li, C., Rijn, M.V., The retinoic acid synthesis gene ALDH1a2 is a candidate tumor suppressor in prostate cancer (2005) Cancer Res, 65, pp. 8118-8124Reichman, M.E., Hayes, R.B., Ziegler, R.G., Schatzkin, A., Taylor, P.R., Kahle, L.L., Serum vitamin A and subsequent development of prostate cancer in the first National Health and Nutrition Examination Survey Epidemiologic Follow-up Study (1990) Cancer Res, 50, pp. 2311-2315Touma, S.E., Perner, S., Rubin, M.A., Nanus, D.M., Gudas, L.J., Retinoid metabolism and ALDH1A2 (RALDH2) expression are altered in the transgenic adenocarcinoma mouse prostate model (2009) Biochem Pharmacol, 78, pp. 1127-1138Shmueli, O., Horn-Saban, S., Chalifa-Caspi, V., Shmoish, M., Ophir, R., Benjamin-Rodrig, H., GeneNote: wholegenome expression profiles in normal human tissues (2003) C R Biol, 326, pp. 1067-1072Su, A.I., Wiltshire, T., Batalov, S., Lapp, H., Ching, K.A., Block, D., A gene atlas of the mouse and human protein-encoding transcriptomes (2004) Proc Natl Acad Sci USA, 101, pp. 6062-6067McSorley, L.C., Daly, A.K., Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation (2000) Biochem Pharmacol, 60, pp. 517-526Roberts, E.S., Vaz, A.D.N., Coon, M.J., Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal (1992) Mol Pharmacol, 41, pp. 427-433Abu-Abed, S., Dolle, P., Metzger, D., The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posteriorstructures (2001) Genes Dev, 15, pp. 226-24
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Author Under Sail The Imagination of Jack London, 1893-1902
No full textIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Intro -- Title Page -- Copyright Page -- Dedication -- Contents -- Acknowledgments -- Introduction -- 1. Spirit Truth -- 2. From Absorption to Theatricality and Back Again -- 3. "I Will Build a New Present" -- 4. Sons as Authors -- 5. Fathers as Publishers -- 6. The Daughter as Author -- 7. Lovers as Authors -- 8. At Sea with the Family -- 9. Yellow News, Yellow Stories -- 10. The Return Home -- Notes -- Bibliography -- Index -- About Jay WilliamsIn Author Under Sail, Jay Williams offers the first complete literary biography of Jack London as a professional writer engaged in the labor of writing. It examines the authorial imagination in London's work, the use of imagination in both his fiction and nonfiction, and the ways he defined imagination in the creative process in his business dealings with his publishers, editors, and agents. In this first volume of a two-volume biography, Williams traverses the years 1893 to 1902, from London's "Story of a Typhoon" to The People of the Abyss. The Jack London who emerges in the pages of Author Under Sail is a writer whose partnership with publishers, most notably his productive alliance with George Brett of Macmillan, was one of the most formative in American literary history. London pioneered many author models during the heyday of realism and naturalism, blurring the boundaries of these popular genres by focusing on absorption and theatricality and the representation of the seen and unseen. London created an impassioned, sincere, and extremely personal realism unlike that of other American writers of the time. Author Under Sail is a literary tour de force that reveals the full range of London as writer, creative citizen, and entrepreneur at the same time it sheds light on the maverick side of machine-age literature.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
- …
