101,420 research outputs found
McDevitt, Thomas (Birth, 1875-12-14)
5688/Pg.198/1875/M W/U.S./U.S./T. Brockman, MDOriginal record filed in drawer labeled 'MCDEVITT-MCGRATH'
McDevitt, Clara M. (Death, 1900-02-09)
Address: 275 McCormack St.Age at death: 13 yrs.Pg 14/1900/167/F W S/Ky./Dr. R. M. Stewart/T. Mulvihill/St. Joseph's NewOriginal record filed in drawer labeled 'MCDEVITT-MCGRATH'
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The development of microbead-based immunoassays: an application of the electronic taste chip
textThere are many people I would like to acknowledge for making graduate school a
gratifying and challenging experience. First, I owe many thanks to my supervisor, Dr.
John T. McDevitt, for his guidance and leadership from the very start. I have learned
many valuable lessons, both on a scientific and personal level, from our discussions. I
also hope to someday emulate his democratic nature and controllability during times of
crises. Furthermore, I would like to express my admiration in the creativity and
scientific-aptitude shown by Dr. McDevitt , Dr. Jason Shear, Dr. Eric Anslyn and Dr.
Dean Neikirk in creating the “Electronic Taste Chip” project. I know someday, if not
already, this research will come to fruition and benefit the lives of many people. Indeed,
I am grateful to have been a part of this intriguing, cutting-edge technology.
I would also like to acknowlege Dr. Dean Neikirk and coworkers for providing
the McDevitt lab with a supply of silicon chips, Ginger Gillan for help in the early stages
of immunology protocol development, and Jorge Wong who has contributed directly for
the generation of the superporous beads as described in Chapters 3 and 4. Dr. Bruce
Walker and Dr. William Rodriguez from the Harvard Medical School are thanked for
useful discussion regarding infectious disease detection. I would also like to
acknowledge the National Science Foundation IGERT Program for access to their
research facilities at the University of Texas at Austin and the opportunity to meet with
other excellent scientists. Although the classes and activities required more time, I feel I
have gained an edge over others and feel as I am part of a very well respected program.
Finally, I want to recognize my mother, father and sisters. Their support and belief in me
has, and always will be, at the heart of my accomplishments.Chemistry and BiochemistryChemistr
Letter, [Author unclear] to Paulina T. Merritt
Handwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Standardized factor loadings and factor correlations in ATQ2-LT
Updated figure for the article “The Chess–Thomas Adult Temperament Questionnaire: Psychometric properties of the Lithuanian version”:
Lazdauskas, T., & McDevitt, S. C. (2023). The Chess–Thomas Adult Temperament Questionnaire: Psychometric properties of the Lithuanian version. Social Sciences, 12(2), Article e52. https://doi.org/10.3390/socsci12020052</p
Handwritten biographical information on Paulina T. McClung Merritt
A handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
IFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
The article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
In this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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