1,721,040 research outputs found
Active Generation of Logical Rules for POMCP Shielding
Full text linkWe consider the popular Partially Observable Monte-Carlo Plan- ning (POMCP) algorithm and propose a methodology, called Active XPOMCP, for generating compact logical rules that represent prop- erties of the control policy. These rules are then used as shields to prevent POMCP from selecting unexpected actions, with useful implications on the security and trustworthiness of the algorithm. Contrary to state-of-the-art methods, Active XPOMCP does not require a previously generated set of belief-action pairs to generate the logical rule, but it actively generates this data in an information- efficient way by querying the algorithm. Active XPOMCP reduces the number of beliefs needed to generate accurate rules with re- spect to state-of-the-art methods, and it allows to produce more accurate shields when few belief-action samples are available
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Systemic passive transfer studies using IgM monoclonal antibodies to sulfatide
No full textWe present a patient with benign IGM-lambda anti-Sulfatide (SUL) whose neuropathy was transferred in newborn rabbits. The patient's clinico-pathological picture of anti-SUL-associated demyelinating neuropathy is reported. The monoclonal IgM antibodies prepared by Tatum's method, that retained their biological activity, were passively transferred to newborn rabbits. The passive transfer produced demyelinating nerve lesions very similar to the donor antibody neuropathy. In experimental lesions we observed the human IgM anti-SUL antibodies binding to Schmidt-Lanterman incisures and nodes of Ranvier. We postulate that the myelin-specific and complement-dependent lesions observed in the peripheral nerve support the potential demyelinating role of anti-SUL antibodies. Moreover, the pattern of the antibody binding to the perineuronal sheath of satellite cells in dorsal root ganglia strengthen the hypothesis that anti-SUL antibodies may have a pathogenetic role in this sensorimotor syndrome
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