1,221 research outputs found
About twin primes and distribution of primes
No full textThis paper give us a demonstration of twin primes conjecture using approximation of function �(iupsilon) that we introduce in section 6. Section 1-5 give us introduction to terminology and a clarification on (iupsilon) terms. In particular section
5 is really important because of its Lemma. Section 7 reassume foregoing explanations and it give us two theorems and one corollary;the theorem 7.2 give us exact approximation of twin primes counting function
How to study sleep apneas in mouse models of human pathology
No full textSleep apnea, the most widespread sleep-related breathing disorder (SBD), consists of recurrent episodes of breathing cessation during sleep. This condition can be classified as either central (CSA) or obstructive (OSA) sleep apnea, with the latest being the most common and toxic. Due to the complexity of living organisms, animal models and, particularly, mice still represent an essential tool for the study of SBD. In the present review we first discuss the methodological pros and cons in the use of whole-body plethysmography to coupling respiratory and sleep measurements and to characterize CSA and OSA in mice; then, we draw an updated and objective picture of the methods used so far in the study of sleep apnea in mice. Most of the studies present in the literature used intermittent hypoxia to mimic OSA in mice and to investigate consequent pathological correlates. On the contrary, few studies using genetic manipulation or high-fat diets investigated the pathogenesis or potential treatments of sleep apnea. To date, mice lacking orexins, hemeoxygenase-2, monoamine oxidase A, Phox2b or Cdkl5 can be considered validated mouse models of sleep apnea. Moreover, genetically- or diet-induced obese mice, and mice recapitulating Down syndrome were proposed as OSA models. In conclusion, our review shows that despite the growing interest in the field and the need of new therapeutical approaches, technical complexity and inter-study variability strongly limit the availability of validated mouse of sleep apnea, which are essential in biomedical research
Established and Outsiders at the Same Time - Self-Images and We-Images of Palestinians in the West Bank and in Israel
No full textPalestinians frequently present a harmonizing and homogenizing we-image of their own national we-group, as a way of counteracting Israeli attempts to sow divisions among them, whether through Israeli politics or through the dominant public discourse in Israel. However, a closer look reveals the fragility of this homogenizing we-image which masks a variety of internal tensions and conflicts. By applying methods and concepts from biographical research and figurational sociology, the articles in this volume offer an analysis of the Middle East conflict that goes beyond the polar opposition between “Israelis” and “Palestinians”. On the basis of case studies from five urban regions in Palestine and Israel (Bethlehem, Ramallah, East Jerusalem, Haifa and Jaffa), the authors explore the importance of belonging, collective self-images and different forms of social differentiation within Palestinian communities. For each region this is bound up with an analysis of the relevant social and socio-political contexts, and family and life histories. The analysis of (locally) different figurations means focusing on the perspective of Palestinians as members of different religious, socio-economic, political or generational groupings and local group constellations – for instance between Christians and Muslims or between long-time residents and refugees. The following scholars have contributed to this volume: Ahmed Albaba, Johannes Becker, Hendrik Hinrichsen, Gabriele Rosenthal, Nicole Witte, Arne Worm and Rixta Wundrak. Gabriele Rosenthal is a sociologist and professor of Qualitative Methodology at the Center of Methods in Social Sciences, University of Göttingen. Her major research focus is the intergenerational impact of collective and familial history on biographical structures and actional patterns of individuals and family systems. Her current research deals with ethnicity, ethno-political conflicts and the social construction of borders. She is the author and editor of numerous books, including The Holocaust in Three Generations (2009), Interpretative Sozialforschung (2011) and, together with Artur Bogner, Ethnicity, Belonging and Biography (2009)
Gendered Adaptations: Canadian Rewritings of Classical Texts. Author-Translator Conference 2010, University of Swansea, Wales
No full textQuantum many-body scars : realizations and applications
No full textauthor: Gabriele Calliari, BScMasterarbeit Universität Innsbruck 202
The Last Bastion of Architecture
No full textThe essay is a critical interpretation of Rem Koolhaas' theory of Bigness. In fact, of the theories that have best marked the development of architectural culture since World War II – from those of the Smithsons to Rossi, from Eisenman to Venturi and Scott Brown – Rem Koolhaas’s theory of Bigness has probably, more than any other, investigated the intrinsic possibilities of architecture at the end of the 20th century. In light of the number of pseudotheories that have largely characterized the last decade, Bigness is the last constituent fact of recent history: an extremely lucid attempt to draw to a conclusion a history that goes back to the very invention of the modern city, comparing it with architecture’s own immutable core, its physicality, even exposing the theory of Bigness itself to the risk of total failure. The essay investigates the development of the theory of Bigness from its incubation in Koolhaas’s book Delirious New York in 1978, to the "official" presentation in S,M,L,XL in december 1995. The essay presents some parts of the PhD research "L'architettura dei libri. Progetto, scrittura, editoria nella ricerca architettonica contemporanea", developed by the author at Università degli studi G. D'Annunzio, Chieti, Facoltà di Architettura di Pescara, in 2001-2004.
Log 7 Winter/Spring 2006 includes essays of Richard Anderson, Marie J. Aquilino, Amos Gitai, Pier Vittorio Aureli, Manuel Orazi, Jean-Louis Cohen, William Drenttel, Peter Eisenman, Luis Fernandez-Galiano, John Kaliski, Sabir Khan, Reinhold Martin, Gabriele Mastrigli, Deborah Richmond, Julie Rose, Paul Virilio, Eyal Weizman, Mirko Zardini.
Log 7
Winter/Spring 2006
Co-edited by Denise Bratton
Saggi di Richard Anderson, Marie J. Aquilino, Amos Gitai,
Pier Vittorio Aureli, Manuel Orazi, Jean-Louis Cohen, William Drenttel, Peter Eisenman, Luis Fernandez-Galiano, John Kaliski, Sabir Khan, Reinhold Martin, Gabriele Mastrigli, Deborah Richmond, Julie Rose, Paul Virilio, Eyal Weizman, Mirko Zardini
Quantum many-body scars : realizations and applications
No full textauthor: Gabriele Calliari, BScMasterarbeit Universität Innsbruck 202
Quantum many-body scars : realizations and applications
No full textauthor: Gabriele Calliari, BScMasterarbeit Universität Innsbruck 202
Autonomic Mechanisms Of Blood Pressure Alterations During Sleep In Orexin/Hypocretin-Deficient Narcoleptic Mice
No full textSTUDY OBJECTIVES: increases in arterial pressure (AP) during sleep and smaller differences in AP between sleep and wakefulness have been reported in orexin (hypocretin)-deficient mouse models of narcolepsy type 1 (NT1) and confirmed in NT1 patients. We tested whether these alterations are mediated by parasympathetic or sympathetic control of the heart and/or resistance vessels in an orexin-deficient mouse model of NT1.METHODS: 13 orexin knock-out (ORX-KO) mice were compared with 12 congenic wild-type (WT) mice. The electroencephalogram, electromyogram, and AP of the mice were recorded in the light (rest) period during intraperitoneal infusion of atropine methyl nitrate, atenolol, or prazosin to block muscarinic cholinergic, beta1-adrenergic, or alpha1-adrenergic receptors, respectively, while saline was infused as control.RESULTS: AP significantly depended on a 3-way interaction among the mouse group (ORX-KO vs WT), the wake-sleep state, and the drug or vehicle infused. During the control vehicle infusion, ORX-KO had significantly higher AP values during REM sleep, smaller decreases in AP from wakefulness to either non-rapid-eye-movement (non-REM) sleep or REM sleep, and greater increases in AP from non-REM sleep to REM sleep compared to WT. These differences remained significant with atropine methyl nitrate, whereas they were abolished by prazosin and, except for the smaller AP decrease from wakefulness to REM sleep in ORX-KO, also by atenolol.CONCLUSIONS: sleep-related alterations of AP due to orexin deficiency significantly depend on alterations in cardiovascular sympathetic control in a mouse model of NT1
Airola (BN), chiesa monastica di San Gabriele
No full textAnalysis of the paintings of the monastic church of San Gabriele (near Benevento) recently discovered by the Author under the convent of the Passionist Fathers on the hill of Monteoliveto (11th century). Apsidal themes: Virgin enthroned with saints, Transfiguration, Deesis (?); on the neighboring walls: hagiographic scene with Saint Nicholas, Saint Theodore on horseback piercing the dragon, Pentecost (?)
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