55 research outputs found
Relapse of curve of Spee leveling with continuous archwire appliance in different vertical skeletal pattern: a retrospective study
No full textTo determine the relapse of the leveling of curve of Spee with edgewise preadjusted appliance in different skeletal vertical pattern. The parent sample of 309 subjects, drawn from the database of the Department of Orthodontics of the University of Rome Tor Vergata, was reduced to the
final sample of 60 subjects (27 M and 33 F; mean age 19.2) by the application of the exclusion criteria. All subject showed a curve of SPEE ≥ 2 mm, a skeletal Class I or Class II patterns and they underwent preadjusted edgewise therapy. The subjects were grouped according to their facial types
based on their pretreatment cephalometric values for y-axis, FMA, and SN^GoGn angle. The arch leveling was measured by the changes in the measurements of the distances of L1, L4, L6 and L7 to MP (Go-Gn). The deepest point of COS was measured on the digital dental casts. Anova test was used to determine the differences between the groups at T1-T2_T3. No statistically significant differences were shown between the groups for the skeletal features. IMPA was significantly increased at T2 in low-angle group. L1-MP showed statistically significant differences at T2 between low and high-angle group. Low-angle group showed statistically significant differences at T3 in COS and OVB value respect to high-angle groups. The levelling of COS was stable in high-angle group in the long-term, on the contrary increased values of COS and OVB was showed post-treatment by low-angle groups due to relapse of L1-MP and IMPA parameters
The first statewide, open access dataset tracking public records requests in New Jersey
No full textState freedom of information laws are vital mechanisms for providing public access to government records and supporting civic engagement through the effectuation of a public policy of transparency at the state level within the United States, not unlike their federal counterpart, the Freedom of Information Act (FOIA). New Jersey state law facilitates public access to government records under the Open Public Records Act (OPRA). Codified at N.J.S.A. 47:1A-1 et seq., OPRA applies to state, county and local public authorities but exempts the judicial and legislative branches from its disclosure requirements. Since OPRA took effect in 2002, it has been difficult to track the full extent of law's impact across New Jersey's 21 counties, 565 municipalities, and numerous state agencies, school districts and independent authorities, all of which must individually respond to requests under the law. To the best of the author's knowledge, no official source has compiled detailed metadata tracking the content and disposition of OPRA requests at the state, regional and municipal levels within New Jersey using individual requests, and authorities rarely proactively disclose their responses to requests they receive, necessitating further data collection to support research into the impacts of this law. This article presents the OPRAmachine dataset: data containing detailed metadata on public records requests submitted to state & local public authorities in New Jersey since October 2017 collected through the implementation of information and communication technologies (ICT) to facilitate the freedom of information request process. The data was collected using an open-source web interface that allowed users to submit an OPRA request to public authorities, with responses stored in a database and made available via the internet. After their request received a response, users were asked to answer a single survey question describing the status of their request, with their answer used to classify the request. Descriptive statistics, tables and frequencies were produced for the dataset and are included in this article. These data will assist state policymakers and other interested parties with assessing trends in OPRA requests across multiple types of public authorities & geographic regions. These data can inform more efficient government records management procedures, foster civic engagement by increasing government transparency and can inform the development of possible reforms to the OPRA law by showing trends in requests & responses that can be used to evaluate the law's implementation throughout the state.Peer reviewe
Renato Rozzi\u27s critical reflection between subjectivity, history, and society
No full textIn the article, the author talks about his relationship with the man and his work. Interested in social history, he favors this aspect of the master\u27s manifold activity, being the prevailing topic of their long common dialogue. In the narrative, the author highlights Rozzi\u27s fidelity to some fundamental values, his passion for social sciences, particularly for depth psychology, as well as his original methodological framework, focusing on some significant results of his socio-historical analysis concerning the peasant and worker worlds, the destructiveness of labor, and the contemporary history of his city. He also details Renato Rozzi\u27s critique of the traditional rural world\u27s subordination, his explanation of the profound causes of the Fordist factory workers\u27 uprising, his proposal of a new idea of human labor, and his aspirations for a more open urban society
MicroRNAs miR-584-5p and miR-425-3p Are Up-Regulated in Plasma of Colorectal Cancer (CRC) Patients: Targeting with Inhibitor Peptide Nucleic Acids Is Associated with Induction of Apoptosis in Colon Cancer Cell Lines
No full textLiquid biopsy has dramatically changed cancer management in the last decade; however, despite the huge number of miRNA signatures available for diagnostic or prognostic purposes, it is still unclear if dysregulated miRNAs in the bloodstream could be used to develop miRNA-based therapeutic approaches. In one author’s previous work, nine miRNAs were found to be dysregulated in early-stage colon cancer (CRC) patients by NGS analysis followed by RT-dd-PCR validation. In the present study, the biological effects of the targeting of the most relevant dysregulated miRNAs with anti-miRNA peptide nucleic acids (PNAs) were verified, and their anticancer activity in terms of apoptosis induction was evaluated. Our data demonstrate that targeting bloodstream up-regulated miRNAs using anti-miRNA PNAs leads to the down-regulation of target miRNAs associated with inhibition of the activation of the pro-apoptotic pathway in CRC cellular models. Moreover, very high percentages of apoptotic cells were found when the anti-miRNA PNAs were associated with other pro-apoptotic agents, such as sulforaphane (SFN). The presented data sustain the idea that the targeting of miRNAs up-regulated in the bloodstream with a known role in tumor pathology might be a tool for the design of protocols for anti-tumor therapy based on miRNA-targeting molecules
Leveling the curve of Spee: comparison between continuous archwire treatment and Invisalign system: a retrospective study
No full textMorphometric analysis of the palatal shape and arch dimension in subjects with palatally displaced canine
No full textObjectives: The aim of this study is to analyse the morphological variations of the palate shape and maxillary arch dimension in a group of subjects with unilaterally or bilaterally impacted maxillary canines compared with a control group, using three-dimensional (3D) geometric morphometric. Materials: The subject of this study consisted of pre-treatment records of 46 (18 males and 28 females) patients with one or both canines palatally displaced. A control group of 26 subjects was selected from a list of orthodontic patients at the same dental hospital. The subjects were divided in two study groups: unilateral palatally displaced canine (UPDC) and bilateral palatally displaced canine (BPDC). Study casts were scanned to analyse the palate’s shape and maxillary arch dimension. The 3D geometric morphometric analysis was used to study the entirety of the shape of the palate.The virtual 3D models were measured with a specific software to analyse the maxillary arch dimension. (VAM, Vectra; Canfield Scientific, Fairfield, New Jersey, USA).
Results: When comparing the groups with the geometric morphometrics analysis, no significant palatal shape change was found. For the analysis of linear measurements, only a significant reduction of intercanine width was found in the UPDC and BPDC groups when compared with the control subjects.
Conclusions: Patients with palatally displaced permanent canine showed no maxillary transverse constriction or variation in palatal vault morphology but the absence of permanent teeth was associated with a reduction in the intercanine width
Leveling the curve of Spee with continuous archwire appliances in different vertical skeletal patterns: A retrospective study
No full textIntroduction: The aim of this study was to determine the effects of the leveling of the curve of Spee in subjects treated with preadjusted appliances in different skeletal vertical patterns. Methods: The study sample consisted of 90 white patients (39 male, 51 female; age, 19 years 4 months +/- 1 year 9 months), with a curve of Spee of 2 mm or greater before treatment. They were categorized into 3 groups: low-angle group (30 subjects; 12 male, 18 female; age, 19 years 1 month +/- 1 year 4 months), normal-angle group (30 subjects; 14 male, 16 female; age, 19 years 6 months +/- 2 years 1 month), and high-angle group (30 subjects; 13 male, 17 female; age, 19 years 7 months +/- 1 year 5 months) by their vertical facial types. Cephalometric parameters were used to evaluate the different dental movements after treatment. The curve of Spee was measured on digital dental casts. Analysis of variance was used to determine any differences between the changes in the groups with time. Results: For the skeletal variables, no significant modifications were found in the 3 groups. For the dentoalveolar variables, the low-angle group showed significant buccal movements and intrusion of the mandibular incisors. The high-angle group had greater extrusion of the posterior teeth associated with uprighting of the first and second molars. Conclusions: In low-angle subjects, leveling of the curve of Spee occurs through buccal movement and intrusion of the mandibular incisors; in high-angle subjects, it occurs through extrusion and uprighting of the posterior teeth
Non-smooth Dynamic Analysis of Local Seismic Damage Mechanisms of the San Felice Fortress in Northern Italy
No full textAbstractThe May 2012 seismic swarm, with epicenter in the Modena plane, in Northern Italy, had severe consequences on the historical buildings of the area. In particular, the fortified structures suffered specific, recurring damage and collapse mechanisms. The present paper deals with the case of the San Felice sul Panaro Fortress, which saw the collapse of 4 out of 5 towers and many other global and local effects. The work starts with an in-depth knowledge path, as a fundamental premise for a conscious intervention. The combination among historical analysis of the building, seismic history of the site, materials and pathological survey, structural identification, on-site inspections and tests, allowed to interpret the crack pattern and to identify the damage mechanisms activated by the earthquake, successively examined with specific structural analyses. In particular, the present paper concentrates on the numerical modelling of the identified local mechanisms, adopting a type of analysis first developed at the University of Parma for applied mechanics, based on the use of non-smooth dynamics software, through a Differential Variational Inequalities (DVI) formulation specifically developed for the 3D discrete elements method. It allows to follow large displacements and the opening and closure of cracks in dynamic field. Once the modelling instrument was calibrated, thanks to the comparison with the real damages previously inspected, it was also applied to foresee the behavior of the same mechanisms with different actions and with different types of strengthening
Dentoskeletal effects of rapid maxillary expander therapy in early mixed dentition patients with different vertical growing patterns without posterior crossbite: a retrospective study
No full textDirac Equation-Based Formulation for the Quantum Conductivity in 2D-Nanomaterials
No full textStarting from the four component-Dirac equation for free, ballistic electrons with finite mass,
driven by a constant d.c. field, we derive a basic model of scalar quantum conductivity, capable of
yielding simple analytic forms, also in the presence of magnetic and polarization effects. The classical
Drude conductivity is recovered as a limit case. A quantum-mechanical evaluation is provided for
parabolic and linear dispersion, as in graphene, recovering currently used expressions as particular
cases. Numerical values are compared with the ones from the literature in the case of graphene under
d.c. applied field. In particular, the effect of the sample length and field strength on the conductivity are highlighted
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