102,206 research outputs found
Montalcino e il suo Brunello : evoluzione e affermazione
No full textThere is a crucial question, related to the reasons why Montalcino, a land where its wine is appreciated for centuries, until the end of the Sixties of the Twentieth Century, has not developed the wine potential production that it held. It is a complex process which interweaves the most important historical events of the Italian Twentieth Century and often played a key role in the realization of the enormous heritage that Montalcino people had at their disposal. Two world wars, the economic boom of the Fifties and the serious state of crisis, in which the countryside went through, didn’t certainly encouraged a production that only in the Eighties became a real source of pride for the Italian viticulture in the world. The winning formula for Brunello di Montalcino was the fellowship between tradition and marketing, respectively represented by Biondi Santi family and Villa Banfi, after having achieved the authorization for DOC before and DOCG after. The history of this famous wine and men, who have been able to build with wise dedication the value and image of Montalcino, outlines a process in which the original values of the rural world are completed in a more modern approach to doing business. Even after the unpleasant events of Brunellopoli, Montalcino, already strong and aware of the immense heritage in its possession, managed to release an icon that, though for short time, was likely to be compromised.Abordant la question de la naissance et de l’évolution d’un territoire viticole d’excellence tel le Montalcino, s’impose une interrogation de fond : pourquoi cette terre, dont ses vins sont appréciés depuis des siècles, n’a pas développé entièrement son potentiel productif jusqu’à la fin des années Soixante du XXe siècle ? La réponse remporte à un parcours complexe étroitement lié aux événements historiques italiens les plus importants du siècle dernier, lesquels ont joué un rôle clé dans la pris de conscience parmi les habitants de Montalcino de l’immense patrimoine dont ils disposent. Deux guerres mondiales, le boom économique des années Cinquante et l’état de crise des campagnes ont empêché l’évolution productive du vin, qui devienne une véritable source de fierté pour la viticulture italienne seulement dans les années Quatre-vingt. La formule gagnante pour le Brunello di Montalcino a été la liaison entre la tradition et la commercialisation, respectivement représentées par la famille Biondi Santi et Villa Banfi, après avoir obtenu les appellation d’origine DOC et, ensuite, DOCG. L’histoire de ce vin célèbre et des hommes qui ont su construire avec dévouement et compétence la valeur et l’image de Montalcino esquisse un chemin structuré, où les valeurs originelles du monde rural se sont combinées avec une approche plus moderne de faire des affaires. Même après les événements malheureux de Brunellopoli du 2008, Montalcino, désormais solide et consciente de l’immense richesse qu’il possède, a réussi à racheter une image, quoique pour peu de temps, a risquée d’être irrémédiablement compromise
Prioritisation of aquatic invasive alien plants in South America with the US Aquatic Weed Risk Assessment
No full textForty South American aquatic plant species were selected and categorised in four a priori status classes (alien naturalised, alien invasive, native and absent) according to expert opinion, for 16 South American regions (Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Falklands Islands, French Guiana, Galapagos, Guyana, Paraguay, Peru, South Georgia and South Sandwich Islands, Suriname, Uruguay and Venezuela). The 40 aquatic plant species were assessed using the US Aquatic Weed Risk Assessment (USAqWRA) scheme for each of the 16 South American regions, for a total number of 644 assessments and for South America (153 assessments). The method was benchmarked against expert opinion (invasive, non-invasive). We ranked 17 of them as naturalised, and 15 as invasive species in at least one South American region. The USAqWRA distinguished between non-invaders and invaders with an overall accuracy of 84.9% in South America and 54.1% in the 16 regions, with areas under the curves equal to 0.893 and 0.853, at a threshold score of 51.5 and 43.5, respectively. The study highlights that the USAqWRA could represent a suitable screening protocol to prioritise aquatic species that have the potential to cause negative impacts, prevent attempts of introduction and to manage risky aquatic plants in South America
Lead content in abortion material from urban women in early pregnancy
No full textLead concentration was determined in abortion material obtained from non-professionally exposed women following legal abortions. Furthermore, lead and free erythrocyte porphyrin levels in mother's blood were measured. Under conditions of apparent "normal" lead exposure, we detected lead levels in abortion products which were between 0.07 and 5.29 micrograms/g dry weight with a geometric mean of 1.27. No significant correlation was observed between the parameters measured in mother's blood and lead content in the specimens of the first trimester. The influence of different factors, such as smoking, area of residence, gestational age and parity, was also investigated. None of these factors showed a contributory effect on the total variation of lead in abortion material. From these data, we can conclude that, at least in our population, lead does not accumulate in human embryos/fetuses in the first trimester of pregnancy
Alveolar rhabdomyosarcoma of the uterine cervix. A case report confirmed by FKHR break-apart rearrangement using a fluorescence in situ hybridization probe on paraffin-embedded tissues.
No full textAlveolar rhabdomyosarcoma (ARMS) is a very rare malignant soft tissue tumor found in the uterine cervix. In fact, to our knowledge, only 3 cases have previously been described in the literature. A 49-year-old premenopausal woman who had a history of vaginal bleeding underwent hysterectomy for multiple uterine nodules. Pathologic examination showed multiple leiomyomas in the uterus and ARMS in the cervix. An FKHR break-apart rearrangement by fluorescence in situ hybridization (FISH) probe on paraffin-embedded tissues identified specific chromosomal abnormalities. Systemic chemotherapy and pelvic irradiation were also performed. She remains in clinical remission from neoplastic recurrences 14 months after surgery. The literature has been reviewed; the histologic differential diagnosis of this rare lesion has been discussed and FISH has been suggested to be useful in differentiating ARMS from other poorly differentiated round cell tumors
GEOGRAFIE DEL VINO: COSTRUZIONE STORICA E PATRIMONIALIZZAZIONE DEI PAESAGGI VITICOLI
No full textThis research project is supposed to face up viticulture in a complex, epistemological framework. As Dickenson and Salt affirm the geography of the wine «may be studied from a variety of perspectives and encompasses the influence of the physical environment, historical diffusion of the vine and viticulture, economic geographies of cultivation and marketing, political influences on trade and production, and cultural perceptions of landscapes, product and people». After all, already in the Latin etymology of viticulture exists a deep content hiatus that imposes to consider two fair enough different concepts; indeed, culture may refer to cultivation and care. Therefore, it is crucial to understand how viticulture must be considered and to show the way its dichotomic nature may suggest distant methodologies of investigation.
After having underlined the epistemological framework of viticulture in relationship to geography and given the interpretative tools of the research, I analyzed the construction and the evolution of some viticultural landscapes (Montalcino, Barolo, Bolgheri and the Côte d’Or) whose choice depends on the dynamics that regarded their production (characterized by a particular propensity to commercialization), the relationships and the differences among them and finally the essential relationship that wine creates with its territory of origin. The role of the tradition represents the fil rouge that links these experiences and it declines in a different perspective according to the realities I analyzed. However, for each of them, it has been fundamental the role developed by a forerunner; indeed, Ferruccio Biondi for Brunello di Montalcino, Juliette Colbert-Falletti for Barolo and Mario Incisa della Rocchetta for the Sassicaia have not only contributed to the creation of a wine but generally to the development of a whole territory that is identified today in the cultivation of the grapevine.
Finally, in virtue of such a rooted and shared historical construction, these territories take part in the processes of patrimonialization that are characterizing some wine regions to a global scale. Following different criterions of classification, where however viticulture covers a preponderant aspect, Val d’Orcia, Langhes and the climats de Bourgogne are considered from the UNESCO a human world heritage to safeguard while Bolgheri has been inserted by Regione Tuscana in the catalog of the historical rural landscapes; in all these cases, independently from who promoted the patrimonialization, the aim is clear: to allow the future generations to enjoy the cultural and environmental wealth that distinguish them. The wine landscapes are reported to be the ones that underwent fast and important transformations. Moving from this, I underline the debate around the relationship between patrimonialization (considered as a specific process of conservation) and the general transformation of the landscape. From this perspective, the criterions of patrimonialization adopted for the viticultural landscapes seem not to consider the eventuality of one change in the case wine shouldn’t play the social and economic role that it has nowadays. What would it happen in that case
Functional genetic variation of the cannabinoid receptor 1 and cannabis use interact on prefrontal connectivity and related working memory behavior
No full textCannabinoid signaling is involved in different brain functions and it is mediated by the cannabinoid receptor 1 (CNR1), which is encoded by the CNR1 gene. Previous evidence suggests an association between cognition and cannabis use. The logical interaction between genetically determined cannabinoid signaling and cannabis use has not been determined. Therefore, we investigated whether CNR1 variation predicts CNR1 prefrontal mRNA expression in postmortem prefrontal human tissue. Then, we studied whether functional variation in CNR1 and cannabis exposure interact in modulating prefrontal function and related behavior during working memory processing. Thus, 208 healthy subjects (113 males) were genotyped for the relevant functional SNP and were evaluated for cannabis use by the Cannabis Experience Questionnaire. All individuals performed the 2-back working memory task during functional magnetic resonance imaging. CNR1 rs1406977 was associated with prefrontal mRNA and individuals carrying a G allele had reduced CNR1 prefrontal mRNA levels compared with AA subjects. Moreover, functional connectivity MRI demonstrated that G carriers who were also cannabis users had greater functional connectivity in the left ventrolateral prefrontal cortex and reduced working memory behavioral accuracy during the 2-back task compared with the other groups. Overall, our results indicate that the deleterious effects of cannabis use are more evident on a specific genetic background related to its receptor expression
Il controllo e la prevenzione dell'infezione toxoplasmica in un campione di donne del Comune di Modena: primi risultati
No full textReasoning on LTL on Finite Traces: Insensitivity to Infiniteness
No full textIn this paper we study when an LTL formula on finite traces (LTLf formula)isinsensitivetoinfiniteness,thatis,itcanbe correctly handled as a formula on infinite traces under the assumption that at a certain point the infinite trace starts re- peating an end event forever, trivializing all other propositions to false. This intuition has been put forward and (wrongly) assumed to hold in general in the literature. We define a neces- sary and sufficient condition to characterize whether an LTLf formula is insensitive to infiniteness, which can be automati- cally checked by any LTL reasoner. Then, we show that typical LTLf specificationpatternsusedinprocessandservicemod- eling in CS, as well as trajectory constraints in Planning and transition-basedLTLf specificationsofactiondomainsinKR, are indeed very often insensitive to infiniteness. This may help to explain why the assumption of interpreting LTL on finite and on infinite traces has been (wrongly) blurred. Possibly be- cause of this blurring, virtually all literature detours to Bu ̈chi automata for constructing the NFA that accepts the traces satis- fying an LTLf formula. As a further contribution, we give a simple direct algorithm for computing such NFA
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