1,720,999 research outputs found
Coloquinte. Marzouk (B), Boukef (M. K.), Marzouk (Z.), «Citrullus Colocynthis Schrad», Essaydali, juin 2012, 123, p. 44-54
No full textBonnemain Bruno. Coloquinte. Marzouk (B), Boukef (M. K.), Marzouk (Z.), «Citrullus Colocynthis Schrad», Essaydali, juin 2012, 123, p. 44-54. In: Revue d'histoire de la pharmacie, 99e année, N. 376, 2012. pp. 540-541
Coloquinte. Marzouk (B), Boukef (M. K.), Marzouk (Z.), «Citrullus Colocynthis Schrad», Essaydali, juin 2012, 123, p. 44-54
No full textBonnemain Bruno. Coloquinte. Marzouk (B), Boukef (M. K.), Marzouk (Z.), «Citrullus Colocynthis Schrad», Essaydali, juin 2012, 123, p. 44-54. In: Revue d'histoire de la pharmacie, 99e année, N. 376, 2012. pp. 540-541
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
In Vitro Sprouted Plantlets of Citrullus colocynthis (L.) Schrad Shown to Possess Interesting Levels of Cucurbitacins and Other Bioactives against Pathogenic Fungi
No full textCucurbitacins, structurally different triterpenes mainly found in the members of Cucurbitaceae, possess a vast pharmacological potential. Genus Cucurbita, Cucumis, and Citrullus are affluent in these bioactive compounds, and, amongst them, Citrullus colocynthis (L.) Schrad. is widely exploited in folk medicine, since a huge number of diseases are successfully treated with organic and aqueous extracts obtained from different organs and tissues of the plant. The well-known pharmacological activities of such species have been attributed to its peculiar composition, which includes cucurbitacins and other bioactive molecules; thus, owing to its high importance as a valuable natural resource for pharmaceuticals and nutraceuticals, C. colocynthis propagation and multiplication protocols are considered significant, but the exploitation of its phytochemical potential is limited by the restricted cultivation conditions and the low rate of seed germination in the natural environment; in fact, the assessment of accumulation rate of specific phytochemicals under controlled conditions is still missing. Axenically sprouted plantlets obtained without the use of culture media or the addition of hormones have been evaluated here for the production of bioactive compounds and relevant bioactive features. Our results proved that derived organic extracts contain cucurbitacins and other bioactives, show antioxidant potential, and exert activity against some pathogenic fungi (Candida krusei, C. albicans, C. parapsilosis, C. glabrata, and Aspergillus flavus), supporting the feasibility of a methodology intended to scale-up cultivation of this species as a source of pharmaceutically interesting compounds, achievable from plantlets cultivated under laboratory conditions
Antiproliferative and chemopreventive activity of Citrullus colocynthis Schrad extracts
No full textCitrullus colocynthis Schrad. is an endemic and wild native plant growing in arid
areas in the south of Tunisia. This cucurbitaceae is widely used in Tunisian folk
medicine for treating many diseases such as disorders related to the presence of free
radicals (i.e. inflammatory disorders, rheumatism, hypertension). In fact, recent
studies show that aqueous and acetone extracts of different parts of this plant
possess free radical scavenging and antioxidant properties.
The aim of the present study was to evaluate the antiproliferative and
chemoprotective activity towards DNA oxidative damage of different extract types
(aqueous, petroleum ether, chloroform, ethyl acetate, acetone, methanol) of different
plant parts (seeds, roots, stems, leaves and fruits) at different concentrations
(5÷500μg/ml). We also analyzed the major fraction and three pure products derived
from chromatographic separation of seeds and fruits chloroform extracts.
MTS and alkaline Comet Assay were performed on different kind of human tumor
and normal cell lines (HT29, colon cancer; A549 lung adenocarcinoma; HFL1, fetal
lung fibroblast). On HT29 cells, the chloroform extracts proved to be the more
interesting ones (GI50 values were lower with respect to the other compounds) and,
in particular, the leaves extract with a GI50 of 140μg/ml. This antiproliferative activity,
at the highest concentration tested (500μg/ml) seems to be related to a cytotoxic
effect (Trypan Blue method) and preliminary data obtained with the Tunel assay
suggests the apoptosis pathway involvement. The antiproliferative activity of leaves
chloroform extract was detected also on lung cell lines. In particular we have found
that the chloroform extracts of seeds, stem and fruits lead a higher antiproliferative
activity on tumoral A549 cells with respect to normal HFL1. Regarding the major
fraction and the pure products, only the product P1 exert an antiproliferative activity
(GI50: 160μg/ml) but only on HT29. DNA migration analysis of HT29 treated for 24h
with leaves chloroform extract or the P1 product (0.5÷50μg/ml) didn’t show any
induced DNA damage. The treatment of HT29 with H2O2 (100μM) as a known
oxidative agent, 5 minutes at 0° after 24h of trea tment with leaves chloroform
extract (5μg/ml), showed an antioxidative activity comparable to that of vitamin C
(1μM) as demonstrated by the significant reduction in the detected DNA migration.
Our results strongly support the pharmacological use of C. colocynthis Schrad
- …
