1,721,047 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Understanding The Beneficial Effects Of Doxycycline On The Dystrophic Phenotype Of The Mdx Mouse
No full textIntroduction: The purpose of this study was to better understand the beneficial effects of doxycycline on the dystrophic muscles of the mdx mouse. Methods: Doxycycline (DOX) was administered for 36 days, starting on postnatal day 0, via drinking water. Untreated mdx mice received plain water for the same period and served as a control group. Results: DOX decreased the levels of metalloproteinase-9 and tumor necrosis factor-alpha in the biceps brachii and diaphragm of the mdx mice. It also reduced the total amount of calcium in the muscles studied, concomitant with an increase in the levels of calsequestrin 1. Conclusions: The results show that DOX can affect factors that are important in dystrophic pathogenesis and highlight its potential as a readily accessible therapy in clinical trials for treatment of Duchenne muscular dystrophy. © 2014 Wiley Periodicals, Inc.502283286Bulfield, G., Siller, W.G., Wight, P.A.L., Moore, K.J., X chromosome-liked muscular dystrophy (mdx) in the mouse (1984) Proc Natl Acad Sci USA, 81, pp. 1189-1192Engel, A.G., Yamamoto, M., Fischbeck, K.H., (1994) Myology, 2, pp. 1133-1187. , Dystrophinopathies, Engel AG, Franzini-Armstrong C, editors. New York: McGraw-HillGrounds, M.D., Torrisi, J., Anti-TNF (Remicade) therapy protects dystrophic skeletal muscle from necrosis (2004) FASEB J, 18, pp. 676-682Hodgetts, S., Radley, H.G., Davies, M., Grounds, M.D., Reduced necrosis of dystrophic muscle by depletion of host neutrophils, or blocking TNF alpha function with Etanercept in mdx mice (2006) Neuromuscul Disord, 16, pp. 591-602Machado, R.V., Mauricio, A.F., Taniguti, A.P., Ferretti, R., Neto, H.S., Marques, M.J., Eicosapentaenoic acid decreases TNF-α and protects dystrophic muscles of mdx mice from degeneration (2011) J Neuroimmunol, 232, pp. 145-150Whitehead, N.P., Yeung, E.W., Allen, D.G., Muscle damage in mdx (dystrophic) mice: role of calcium and reactive oxygen species (2006) Clin Exp Pharmacol Physiol, 33, pp. 657-662Nadarajah, V.D., van Putten, M., Chaouch, A., Garrood, P., Straub, V., Lochmüller, H., Serum matrix metalloproteinase-9 (MMP-9) as a biomarker for monitoring disease progression in Duchenne muscular dystrophy (DMD) (2011) Neuromuscul Disord, 21, pp. 569-578Li, H., Mittal, A., Makonchuk, D.Y., Bhatnagar, S., Kumar, A., Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy (2009) Hum Mol Genet, 18, pp. 2584-2598Kumar, A., Bhatnagar, S., Kumar, A., Matrix metalloproteinase inhibitor batimastat alleviates pathology and improves skeletal muscle function in dystrophin-deficient mdx mice (2010) Am J Pathol, 177, pp. 248-260Alameddine, H.S., Matrix metalloproteinases in skeletal muscles: friends or foes? (2012) Neurobiol Dis, 48, pp. 508-518Griffin, M.O., Ceballos, G., Villarreal, F., Tetracycline compounds with non-antimicrobial organ protective properties: possible mechanisms of action (2011) Pharmacol Res, 63, pp. 102-107Minagar, A., Alexander, J.S., Schwendimann, R.N., Kelley, R.E., Gonzalez-Toledo, E., Jimenez, J.J., Combination therapy with interferon beta-1a and doxycycline in multiple sclerosis: an open-label trial (2008) Arch Neurol, 65, pp. 199-204Brown, D.L., Desai, K.K., Vakili, B.A., Nouneh, C., Lee, H.M., Golub, L.M., Clinical and biochemical results of the metalloproteinase inhibition with subantimicrobial doses of doxycycline to prevent acute coronary syndromes (MIDAS) pilot trial (2004) Arterioscler Thromb Vasc Biol, 24, pp. 733-738Lindeman, J.H., Abdul-Hussien, H., van Bockel, J.H., Wolterbeek, R., Kleemann, R., Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells (2009) Circulation, 119, pp. 2209-2216Pereira, J.A., Taniguti, A.P.T., Matsumura, C., Marques, M.J., Santo Neto, H., Doxycycline ameliorates the dystrophic phenotype of skeletal and cardiac muscles in mdx mice (2012) Muscle Nerve, 46, pp. 400-406Bhatnagar, S., Kumar, A., Therapeutic targeting of signaling pathways in muscular dystrophy (2010) J Mol Med, 88, pp. 155-166Terrill, J.R., Boyatzis, A., Grounds, M.D., Arthur, P.G., Treatment with the cysteine precursorl-2-oxothiazolidine-4-carboxylate (OTC) implicates taurine deficiency in severity of dystropathology in mdx mice (2013) Int J Biochem Cell, 45, pp. 2097-2108Fogagnolo, A.M., Minatel, E., Santo Neto, H., Marques, M.J., Effects of fish oil containing eicosapentaenoic acid and docosahexaenoic acid on dystrophic mdx mice (2013) Clin Nutr, 32, pp. 636-642Matsumura, C.Y., Pertille, A., Albuquerque, T.C.P., Santo Neto, H., Marques, M.J., Diltiazem and verapamil protect dystrophin-deficient muscle fibers of mdx mice from degeneration: a potential role in calcium buffering and sarcolemmal stability (2009) Muscle Nerve, 39, pp. 167-176Lau, A.C., Duong, T.T., Ito, S., Wilson, G.J., Yeung, R.S.M., Inhibition of matrix metalloproteinase-9 improves coronary outcome in an animal model of Kawasaki disease (2009) Clin Exp Immunol, 157, pp. 300-309Srivastava, A.K., Qin, X., Wedhas, N., Arnush, M., Linkhart, T.A., Chadwick, R.B., Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathway (2007) J Biol Chem, 282, pp. 35113-35124Uchida, K., 4-Hydroxy-2-nonenala product and mediator of oxidative stress (2003) Prog Lipid Res, 42, pp. 318-343Nelson, M.L., Chemical and biological dynamics of tetracyclines (1998) Adv Dent Res, 12, pp. 5-11Novák, P., Soukup, T., Calsequestrin distribution, structure and function, its role in normal and pathological situations and the effect of thyroid hormones (2011) Physiol Res, 60, pp. 439-452Seok, J., Shaw Warren, H., Cuenca, A.G., Mindrinos, M.N., Baker, H.V., Xu, W., Genomic responses in mouse models poorly mimic human inflammatory diseases (2013) Proc Natl Acad Sci USA, 110, pp. 3507-351
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
L-arginine Enhances Muscle Regeneration After Experimental Envenomation By B. Jararacussu: A Future For Nitric Oxide-based Therapy?
No full textWe investigated whether muscle fiber regeneration would be rescued by exogenous administration of l-arginine, the precursor of endogenous synthesis of nitric oxide. The right tibialis anterioris muscle of adult mice (n = 20) was injected with 80 μg of venom. One group of mice (n = 10) received drinking water containing l-arginine (3.75 mg/ml) and another group (n = 10) did not receive any pharmacological treatment. Two months later, muscle regeneration was evaluated by counting the total number of muscle fibers. We found that in l-arginine-treated mice, muscle regeneration was significantly higher (p < 0.05) than in saline-treated (2.230 ± 478 muscle fibers versus 1.005 ± 134, respectively) although the level of muscle fiber population of uninjured tibialis anterioris muscle (3.121 ± 102) was not attained. These results show that muscle regeneration was significantly facilitated by l-arginine and suggest that pharmacological activators of the NO pathway may be potentially useful for improving muscle regeneration in human envenomation by B. jararacussu. © 2006 Elsevier Ltd. All rights reserved.483353357Anderson, J.E., A role for nitric oxide in muscle repairnitric-oxide mediated satellite cell activation (2000) Mol. Biol. Cell, 11, pp. 1859-1874Anderson, J.E., Vargas, C., Correlated NOS-Iμ and myf5 expression by satellite cells in mdx mouse muscle regeneration during NOS manipulation and deflazacort treatment (2003) Neuromuscul. Disord., 13, pp. 388-396Barton, E.R., Morris, L., Kawana, M., Bish, L.T., Toursel, T., Systemic administration of l-arginine benefits mdx skeletal muscle function (2005) Muscle Nerve, 32, pp. 751-760Bode-Boger, S.M., Muke, J., Surdacki, A., Brabant, G., Boger, R.H., Frolich, J.C., Oral l-arginine improves endothelial function in healthy individuals older than 70 years (2003) Vasc. Med., 8, pp. 77-81Boger, R.H., Bode-Boger, S.M., The clinical pharmacology of l-arginine (2001) Annu. Rev. Pharmacol. Toxicol., 41, pp. 79-99Cantini, M., Giurisato, E., Radu, C., Tiozzo, S., Pampinella, F., Senigaglia, D., Zaniolo, G., Vitiello, L., Macrophage secreted myogenic factors: a promising tool for greatly enhancing the proliferative capacity of myoblasts in vitro and in vivo (2002) Neurol. Sci., 23, pp. 189-194Carlson, B.M., Hansen-Smith, F.M., Magon, D.K., The life history of a free muscle graft (1979) Muscle Regeneration, pp. 493-507. , Mauro A. (Ed), Raven Press, New YorkChargé, S.B.P., Rudnicki, M.A., Cellular and molecular regulation of muscle regeneration (2004) Physiol. Rev., 84, pp. 209-238Cirino, G., Fiorucci, S., Sessa, W.C., Endothelial nitric oxide synthase: the Cinderella of inflammation? (2003) Trends Pharmacol. Sci., 24, pp. 91-95Harris, J.B., Myotoxic phospholipases A 2 and the regeneration of skeletal muscles (2003) Toxicon, 42, pp. 933-945Jorge, M.T., Ribeiro, L.A., O'Connell, J.L., Prognostic factors for amputation in the case of envenoming by snakes of the genus Bothrops (Viperidae) (1999) Ann. Trop. Med. Parasitol., 93, pp. 401-408Luz, M.A.M., Marques, M.J., Santo Neto, H., Impaired muscle regeneration of dystrophin-deficient muscle fibers is caused by exhaustion of myogenic cells (2002) Braz. J. Med. Biol. Res., 34, pp. 691-695Marques, M.J., Luz, M.A.M., Minatel, E., Santo Neto, H., Muscle regeneration in dystrophic mdx mice is enhanced by isosorbide dinitrate (2005) Neurosci. Lett., 382, pp. 342-345Parker, J.D., Parker, J.O., Nitrate therapy for stable angina pectoris (1998) N. Engl. J. Med., 338, pp. 520-531Peek, M., Moran, P., Mendoza, N., Wickramasinghe, D., Kirchhofer, D., Unusual proteolytic activation of pro-hepatocyte growth factor by plasma kallikrein and coagulation factor XIa (2002) J. Biol. Chem., 277, pp. 47804-47809Pisconti, A., Brunelli, S., Di Padova, M., De Palma, C., Deponti, D., Baesso, S., Sartorelli, V., Clementi, E., Follistatin induction by nitric oxide through cyclic GMP: a tightly regulated signaling pathway that controls myoblast fusion (2006) J. Cell Biol., 172, pp. 233-244Qian, W., Makitie, A.A., Witterick, I., Haight, J.S., A comparison between nitric oxide output in the nose and sinuses: a pilot study in one volunteer (2005) Acta Oto-Laryngol, 125, pp. 1080-1085Queiróz, L.S., Santo Neto, H., Rodrigues-Simioni, L., Prado-Franceschi, J., Muscle necrosis and regeneration after envenomation by Bothrops jararacussu snake venom (1984) Toxicon, 22, pp. 339-346Queiróz, L.S., Marques, M.J., Santo Neto, H., Acute local nerve lesions induced by Bothrops jararacussu snake venom (2002) Toxicon, 40, pp. 1483-1486Santo Neto, H., Marques, M.J., Microvessel damage by B. jararacussu snake venom: pathogenesis and influence on muscle regeneration (2005) Toxicon, 46, pp. 814-819Sheehan, S.M., Tatsumi, R., Temm-Gove, C.J., Allen, R.E., HGF is an autocrine growth factor for skeletal muscle satellite cells in vitro (2000) Muscle Nerve, 23, pp. 239-245Tatsumi, R., Hattori, A., Ikeuchi, Y., Anderson, J.E., Allen, R.E., Release of hepatocyte growth factor from mechanically stretched skeletal muscles satellite cells and role of pH and nitric oxide (2002) Mol. Biol. Cell, 13, pp. 2909-2918Teixeira, C.F.P., Zamunér, S.R., Zuliani, J.P., Fernandes, C.M., Cruz-Höfling, M.A., Fernandes, I., Chaves, F., Gutiérrez, J.M., Neutrophils do not contribute to local tissue damage, but play a key role in the skeletal muscle regeneration, in mice injected with Bothrops asper snake venom (2003) Muscle Nerve, 28, pp. 449-459Tidball, J.G., Inflammatory processes in muscle injury and repair (2005) Am. J. Physiol., 288, pp. 345-353Tousoulis, D., Xenakis, C., Tentolouris, C., Davies, G., Antoniades, C., Crake, T., Stefanidis, C., Effects of vitamin C on intracoronary l-arginine dependent coronary vasodilatation in patients with stable angina (2005) Heart, 91, pp. 1319-1323Voisin, V., Sébrié, C., Matecki, S., Yu, H., Gillet, B., Ramonatxo, M., Israel, M., De la Porte, S., l-arginine improves dystrophic phenotype in mdx mice (2005) Neurobiol. Dis., 20, pp. 123-136Wierema, T.K.A., Houben, A.J.H.M., Kroon, A.A., Postma, C.T., Koster, D., van Engelshoven, J.M.A., Smits, P., de Leeuw, P.W., Mechanisms of adenosine-induced renal vasodilatation in hypertensive patients (2005) J. Hypertension, 23, pp. 1731-173
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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