2,949 research outputs found

    Monotherapy and combined therapy of new potential antitumor compounds: antiproliferative activities and biological targets

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    Review article Martins, P., Marques, M., Coito, L., Pombeiro, A.J.L., Baptista, P.V., Fernandes, A.R. 2014. Organometallic Compounds in Cancer Therapy: Past Lessons and Future Directions. Anti-cancer Agents in Medicinal Chemistry 14. PMID: 2517355

    Easter Morning: A.R. Ammons and His Poem Video Recording

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    Audio recording of a poem entitled, "Easter Morning", recited by the poem's author, A.R. Ammons

    A.R Baswedan dan PAl: Potret Nasionalisme Warga Keturunan perspektif sosiopolitik historis

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    In this article, the authors review about A.R. Baswedan and his movement through the Arab Party of Indonesia (PAl). A.R Baswedan is an Arab descendant known as the pioneer of independence of the Republic of Indonesia. The author through historical socio-political studies found that A.R Baswedan is an example of Arabic descent who counter Arabism and views between the Arab descendants and the descendants of indigenous Indonesians are the same or equal and the same fate. They both have one nationality, Indonesia. This fusion attitude in the Indonesian citizenship and nationality equation is evident in its movement within the PAl. Keywords: A.R. Baswedan, Biography, and Thought (PAl

    A.R. Luria: Ideas and Prospects of Their Development in Pedagogical Psychology of the Twenty-first Century

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    A.R. Luria’s ideas are well-known and recognized both in Russia and abroad. Scientists from different countries are actively working in neuropsychology, a part of the psychological science developed by A.R. Luria. The author has shown the relevance and importance of the neuropsychological approach to the pedagogical psychology problems and the availability to choose an adequate educational and nurturing strategy from these standpoints. The study seeks to rethink and assess the importance of A.R. Luria’s main ideas from the modern pedagogical psychology’s standpoints. The characteristic of the main theoretical provisions has been set forth based on the analysis of A.R. Luria’s academic papers and the main directions and prospects for the development of A.R. Luria’s ideas in the modern psychological pedagogical science have been determined. A.R. Luria’s academic papers most sought by the modern researchers have been noted. The study is based on the materials of the thesis researches on the pedagogical psychology problems conducted in the beginning of the twenty-first century, A.R. Luria’s papers, the publications of other researchers who have studied his contribution to the psychological science. The study results show that A.R. Luria has significantly contributed to the development of the pedagogical psychology problems. A.R. Luria’s ideas on the interaction of the humanitarian and science knowledge in the human comprehensive study, the cultural and historical understanding of the psychical functions development, and the language evolution in the music language study for the musical education development seem most promising for the pedagogical psychology development. Note has been taken of the importance of A.R. Luria’s ideas for the elaboration of the relevant problems of the training and development of a person at any age; the study of individual and typical features in mastering a foreign language; the study of the semantics of speech and means of coding meanings in the context of professional training of psychologists and teachers, specialists in the field of artistic creativity. The analysis of A.R. Luria’s main ideas facilitates the deeper understanding of the modern problems of the pedagogical psychology theory and practice

    Incorporation of acceleration effects into the one-dimensional-turbulence model, with application to turbulent combustion and shock-turbulence interactions

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    One-dimensional turbulence (ODT) is a stochastic simulation in which 3D turbulence effects are captured on a notional 1D line of sight by introducing instantaneous spatial re-arrangements (maps) that represent advection by notional turbulent eddies. These eddy events incorporate the possibility of kinetic-energy changes that are equal and opposite to changes of other forms of energy such as the gravitational potential energy change due to a re-arrangement of a vertical density profile. This illustrates that motion aligned with an applied force, in this case gravitation gg, can be associated with energy change. Using this principle, we 1) present a model of turbulence interaction with the dilatational acceleration caused by thermal expansion in flames and show results for a turbulent counterflow flame with comparison to DNS and 2) present a model for shock-induced turbulence and show results for mixing width growth in a shock tube with comparison to experiments

    ODTLES: A multi-scale ansatz for highly turbulent flows

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    We use ODTLES, a multi-dimensional extension of the One-Dimensional-Turbulence model (ODT). ODT describes turbulent advection on a 1D sub-domain using a stochastic process for turbulent advection. These 1D sub-domains are coupled to obtain a 3D approach. ODTLES is applied to channel flow. Preliminary results for the pdf of the wall shear stress are compared to DNS

    Determination Of The Solubility Of Extracts From Vegetable Raw Material In Pressurized Co2: A Pseudo-ternary Mixture Formed By Cellulosic Structure + Solute + Solvent

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    This paper discusses the application of the dynamic method to measure the solubility in pseudo-ternary systems formed by vegetable raw materials (cellulosic structure + solute) and CO2. For aromatic, medicinal, and spice plants, the soluble portion of the solid is formed of essential oils, oleoresins, pigments, and various substances from several other classes of organic compounds. The experimental data were measured in two independent laboratories, using three experimental set-ups, and three vegetable species: clove buds, eucalyptus, and ginger. The solubility for the system clove buds/CO2 varied from 0.220 to 0.277 kg-extract/kg-CO2 for the isotherm of 288.15 K. The ginger extract solubility varied from 2.01 × 10-3 to 7.20 × 10-3 kg-extract/kg-CO2 for pressures of 100-300 bar, and temperatures of 298.15-313.15 K. The eucalyptus solubility for the isobar of 66.7 bar varied from 3.95 × 10-3 to 4.07 × 10-3 kg-extract/kg-CO2. © 2002 Elsevier Science B.V. All rights reserved.2212136Brunner, G., (1994) Gas Extraction: An Introduction to Fundamentals of Supercritical Fluids and the Application to Separation Processes, , Springer, New York, USAMcHugh, M.A., Krukonis, V.J., (1994) Supercritical Fluid Extraction: Principles and Practice, , Butterworth-Heinemann, Newton, USAVernin, G., Verinin, E., Metzger, J., Pujol, L., Parkanyi, C., GC/MS analysis of clove essential oils (1994) Spices, Herbs and Edible Fungi, p. 483. , George Charalambous (Ed.), Elsevier Science, Amsterdam, HollandCraveiro, A.A., Queiroz, D.C., Óleos essenciais e química fina (1993) Química Nova, 16, p. 224Matos, F.J.A., (1998) Farmácias Vivas, , Edições da Universidade Federal do Ceará, Fortaleza, BrazilBartley, J.P., Foley, P., Supercritical fluid extraction of Australian-grown ginger (Zingiber officinale) (1994) Journal of the Science of Food and Agriculture, 66, p. 365Monteiro, A.R., Meireles, M.A.A., Marques, M.O.M., Ginger (Zingiber officinale) essential oil and oleoresin extraction with pressurized CO2: An evaluation of pretreatment and process variables in oil composition (1998) Proceedings of the 5th Meeting on Supercritical Fluids: Natural Products and Materials, 2, p. 515. , M. Perrut (ed.), Nice, FranceBrod, F.D., Oliveira, R., Park, K.J., Estudo de um secador convectivo de fluxo perpendicular e paralelo (2000) Proceedings of the 29th Congresso Brasileiro de Engenharia Agricola - CONBEA 2000, , Fortaleza, CE, CD RomGomide, R., Manual de Operações Unitárias, , Cenpro (Ed.), São Paulo, BrazilJacobs, M.B., (1973) The Chemical Analysis of Food and Products, , Robert Krieger Publishing Co., New York, USARodrigues, V.M., Meireles, M.A.A., Marques, M.O.M., (2000) Determination of the solubility of clove essential oil in CO2: A standardization of the dynamic method, Proceedings of the 5th International Symposium on Supercritical Fluids, , Westin Atlanta, Georgia, USA, CD-RomFerreira, S.R.S., Meireles, M.A.A., Cabral, F.A., Extraction of essential oil of black pepper with liquid carbon dioxide (1993) Journal of Food Engineering, 20, p. 121Sousa, E.M.B.D., Chiavone-Filho, O., Moreno, M.T., Oliveira, H.N., Meireles, M.A.A., Experimental results for the extraction of essential oil from the species Lippia Sidoides in pressurized carbon dioxide (2001) Proceedings of the 2nd International Meeting on High Pressure Chemical Engineering, , TUHH, Hamburg, Germany, CD-RomFrança, L.F., Meireles, M.A.A., Modeling the extraction of carotene and lipids from pressed palm oil (Elaes guineensis) fibers using supercritical CO2 (2000) Journal of Supercritical Fluids, 18, p. 35Monteiro, A.R., Meireles, M.A.A., Marques, M.O.M., Petenate, A.J., Extraction of the soluble material from the shells of the bacuri fruit (Platonia insignis Mart) with pressurized CO2 and other solvents (1997) Journal of Supercritical Fluids, 11, p. 91McLaferty, F.W., Stauffer, D.B., (1989) The Wiley/NBS Registry of Mass Spectral Data, 1-2. , John Wiley and Sons, New York, USAAdams, R.P., (1995) Identification of Essential Oil Components by Gas Chromatography/Mass Spectroscopy, , Allured Publishing Corporation, Illinois, USACollins, C.H., Braga, G.L., Bonato, P.S., (1995) Introdução a Métodos Cromatográficos, , Editora da Unicamp, Campinas, BrazilMatos, F.J.A., (1997) Introdução à Fitoquímica Experimental, , Editora da Universidade Federal do Ceará, Fortaleza, CE, BrazilFreund, R.J., Littell, R.C., (1995) SAS System for Regression - SAS Series in Statistical Applications, , SAS Institute Inc., NC, USASovová, H., Rate of the vegetable oil extraction with supercritical CO2-I. Modeling of extraction curves (1994) Chemical Engineering Science, 49, p. 409Santacesaria, E., Morbidelli, M., Servida, A., Storti, G., Carrà, S., Separation of xylenes on Y zeolites. 2. Breakthrough curves and their interpretation (1982) Ind. Eng. Chem. Proc Esso Des. Dev., 21, p. 446Cathpole, O.J., Berning, R., King, M.B., Measurement and correlation of Packed-Bed axial dispersion coefficients in supercritical carbon dioxide (1996) Ind. Eng. Chem. Res., 35, p. 824Tan, C.-S., Liou, D.-C., Axial dispersion of supercritical carbon dioxide in packed beds (1989) Ind. Eng. Res., 28, p. 1246Monteiro, A.R., (1999) Extração do Óleo Essencial/Oleoresina de Gengibre (Zingiber officinale Roscoe) com CO2 Supercrítico: uma avaliação do pré-tratamento e das variáveis de processo, , Doctoral thesis, FEA - Universidade Estadual de Campinas (Unicamp), Campinas, São Paulo, BrazilZancan, K.C., Marques, M.O.M., Meireles, M.A.A., Petenate, A.J., (2001), TUHH, Hamburg, Germany, CD-RomPovh, N.P., Meireles, M.A.A., Marques, M.O.M., (2001) Supercritical CO2 extraction of essential oil and oleoresin from chamomile (Matricaria recutita [L.] Rauschert), , TUHH, Hamburg, Germany, CD-RomRodrigues, V.M., Marques, M.O.M., Meireles, M.A.A., (2001) Supercritical extraction of essential oil from anise seed (Pimpinella anisum, L) using CO2: Kinetics and equilibrium data, , TUHH, Hamburg, Germany, CD-RomGovidarajan, V.S., (1982) CRC Critical Reviews in Food Science and Nutrition, 17, p. 1. , CRC Press Inc., Florid

    Applying Multi-Criteria Decision Analysis to the Life-Cycle Assessment of vehicles

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    This is a PDF file of an unedited manuscript that has been accepted for publication in Journal of Cleaner Production: The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. The final version will be available at: https://doi.org/10.1016/j.jclepro.2015.05.08

    Electronic Structure Of Amorphous Germanium-nitrogen Alloys: A Uv Photoelectron Spectroscopy Study

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    The valence band and Ge 3d core-level structure of amorphous germanium-nitrogen alloys (a-Ge1-xNx) of various compositions (0 < x < 0.36) have been studied by ultraviolet photoelectron spectroscopy using He I and He II excitation. Two N-related bands centered at about 11 and 5 eV below the Fermi energy are found to evolve in the valence band spectra with increasing x. These are attributed to N 2p bonding and lone-pair states, respectively. A systematic shift and broadening of the Ge 3d core level peaks occurs with increasing x. Analysis of this effect allows for the determination of a N-induced chemical shift per Ge-N bond of 0.30 ± 0.08 eV. For x > 0.22, a significant recession of the top of the valence band sets in, which is correlated by the sudden increase of the optical gap. An asymmetrical widening of the band gap for x > 0.22 is deduced.198-200PART 1136139Chambouleyron, I., Marques, F., Cisneros, J., Alvarez, F., Moehlecke, S., Losch, W., Pereyra, I., (1985) J. Non-cryst. Solids, 77-78, p. 1309Bagratishvili, G.D., Dzhanelidze, R.B., Kurdiani, N.I., Saksaganskii, O.V., (1976) Phys. Status Solidi, 36 A, p. 73Zanatta, A.R., Chambouleyron, I., (1993) Phys. Rev., B48, p. 4560Kärcher, R., Ley, L., Johnson, R.L., (1984) Phys. Rev., B30, p. 1896Guraya, M.M., Ascolani, H., Zampieri, G., Dias Da Silva, J.H., Cantão, M.P., Cisneros, J.I., (1994) Phys. Rev., B49, p. 13446Yeh, J.J., Lindau, I., (1985) At. Dat. Nuc. Dat. Tables, 32, p. 1Comedi, D., Zanatta, A.R., Alvarez, F., Chambouleyron, I., (1995) J. Vac. Sci. Technol., A13, p. 2278Zanatta, A.R., Chambouleyron, I., (1995) Solid State Commun., 95, p. 207Davis, E.A., Piggins, N., Bayliss, S.C., (1987) J. Phys., C20, p. 441

    Author Correction: Imaging-based representation and stratification of intra-tumor heterogeneity via tree-edit distance

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    Martina Sollini and Paola Anna Erba were omitted from the author list in the original version of this Article. The Author Contributions section now reads: “L.C. conceived the pipeline, set up the case study, analysed the results, prepared the figures, and wrote the manuscript. M.P. formulated and tuned the pruned tree edit distance, provided the mathematical proofs and the simulation study, and wrote the manuscript. A.R. contributed to implement the patient representation pipeline. M.S. segmented the Prostate Cancer lesions and extracted the radiomic features for all patients in the case study. P.A.E collected the data and enrolled the patients in the clinical study. F.I. supervised the analyses and the conception of the pipeline. L.C., M.P., A.R. and F.I. reviewed and approved the manuscript.” The original Article and accompanying Supplementary Information file have been corrected.</p
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