30 research outputs found
Ugly Mathematics: Why Do Mathematicians Dislike Computer-Assisted Proofs?
No full textThe Viewpoint column offers readers of The Mathematical Intelligencer the opportunity to write about any issue of interest to the international mathematical community. Disagreement and controversy are welcome. The views and opinions expressed here, however, are exclusively those of the author, and the publisher and editors-in-chief do not endorse them or accept responsibility for them. Viewpoints should be submitted to one of the editors-in-chief, Chandler Davis and Marjorie Senechal
Telling stories and contextualizing lived experiences in the Cuban heritage language and culture: an autoethnography about transculturation
No full textThrough this bi-literacy narrative, the author traces her path to becoming a United States citizen and a language teacher. The lived experiences in both Cuba and the United States include (1) her father’s “one year, one month, and one day” in the Aid-to-Production Camp where young Cuban men—even the most educated— were “recruited” to work in the sugar cane fields, (2) his escape from the island by water, (3) his safe passage to Miami in 1969, (4) his nine years in this country trying to bring his wife and newborn—the author—to permanent residence in California. She includes his written account of liminal passages from one country to another, his graduate studies, and his making of a new life for his family here. Demonstrating the value of the oral tradition and storytelling, the author—now a mother of five—tells readers about her Cuban maternal grandparents’ reading The Bible aloud daily, her mother’s strengths, her own life as a mother, student, and teacher; as well as the tradition of higher education prized by her family and Cuban culture. This auto-ethnographic account tells how Cuban and American values shaped her into the person and teacher that she is today
AORTIC ROOT ENLARGEMENT IN REDO AORTIC VALVE REPLACEMENT WITH PREDICTED PATIENT-PROSTHESIS MISMATCH
No full textMulti-Kernel Appearance Model☆
No full textThis article appeared in a journal published by Elsevier. The attached copy is furnished to the author for internal non-commercial research and education use, including for instruction at the authors institution and sharing with colleagues. Other uses, including reproduction and distribution, or selling or licensing copies, or posting to personal, institutional or third party websites are prohibited. In most cases authors are permitted to post their version of the article (e.g. in Word or Tex form) to their personal website or institutional repository. Authors requiring further information regarding Elsevier’s archiving and manuscript policies are encouraged to visit
Vorinostat differentially alters 3D nuclear structure of cancer and non-cancerous esophageal cells
No full textabstract: The histone deacetylase (HDAC) inhibitor vorinostat has received significant attention in recent years as an ‘epigenetic’ drug used to treat solid tumors. However, its mechanisms of action are not entirely understood, particularly with regard to its interaction with the aberrations in 3D nuclear structure that accompany neoplastic progression. We investigated the impact of vorinostat on human esophageal epithelial cell lines derived from normal, metaplastic (pre-cancerous), and malignant tissue. Using a combination of novel optical computed tomography (CT)-based quantitative 3D absorption microscopy and conventional confocal fluorescence microscopy, we show that subjecting malignant cells to vorinostat preferentially alters their 3D nuclear architecture relative to non-cancerous cells. Optical CT (cell CT) imaging of fixed single cells showed that drug-treated cancer cells exhibit significant alterations in nuclear morphometry. Confocal microscopy revealed that vorinostat caused changes in the distribution of H3K9ac-marked euchromatin and H3K9me3-marked constitutive heterochromatin. Additionally, 3D immuno-FISH showed that drug-induced expression of the DNA repair gene MGMT was accompanied by spatial relocation toward the center of the nucleus in the nuclei of metaplastic but not in non-neoplastic cells. Our data suggest that vorinostat’s differential modulation of 3D nuclear architecture in normal and abnormal cells could play a functional role in its anti-cancer action.The final version of this article, as published in Scientific Reports, can be viewed online at: http://www.nature.com/articles/srep3059
Capital City Farm: modeling a way forward
No full textThis thesis uses an investigation into Capital City Farm, a two-acre urban farm established in 2015 in the City of Trenton, New Jersey to explore the multifaceted challenges urban agriculture faces in urban post-industrial spaces and communities. Despite 2019 being its most successful year in terms of production and programming, the project struggles with sustainable funding, staffing and community engagement. Part One contextualizes Capital City Farm with the concepts of sustainability; resilience; urban issues such as redlining, urban renewal, and gentrification; environmental justice; citizen participation; and urban agriculture in order to understand how urban agriculture may be a means to address the environmental, social, economic, and justice issues in communities like East Trenton.
Part two interrogates Capital City Farm’s recent past and current situation according to Land, Labor, Liquidity, and Leadership strategies. Interviews with Farm stakeholders, regular visits to the Farm property, and a visit to the Trentoniana collection at the Trenton Free Public Library provide the material for this investigation. This section finishes with an evaluation of Capital City Farm and the recent Garden State Agrihood proposal for the community that frames the Farm as in a new community development model. This analysis suggests that, while many facets of the concept of the Farm and the Agrihood are valuable and worth pursuing, the Farm is unsustainable without an adjustment of the Agrihood Board’s commitment to address participation, maintenance, and management.
The final section projects different organizational models the Farm could take: Garden State Agrihood managed cooperative, Garden State Agrihood managed Farm, Non-Profit managed agriculture program, Mercer County managed agriculture park, or just city managed open space. It concludes with a discussion of what could be possible with more study and general lessons learned throughout the investigation that can be applied to the practice of landscape architecture and design of public spaces. Best practices like good communication, community participation, multiple site visits, and intention are even more crucial in communities such as East Trenton. Otherwise, landscape architects and other design professionals risk perpetuating the injustices of the past.M.L.A.Includes bibliographical reference
Cultural-based visual expression: Emotional analysis of human face via Peking Opera Painted Faces (POPF)
No full text© 2015 The Author(s) Peking Opera as a branch of Chinese traditional cultures and arts has a very distinct colourful facial make-up for all actors in the stage performance. Such make-up is stylised in nonverbal symbolic semantics which all combined together to form the painted faces to describe and symbolise the background, the characteristic and the emotional status of specific roles. A study of Peking Opera Painted Faces (POPF) was taken as an example to see how information and meanings can be effectively expressed through the change of facial expressions based on the facial motion within natural and emotional aspects. The study found that POPF provides exaggerated features of facial motion through images, and the symbolic semantics of POPF provides a high-level expression of human facial information. The study has presented and proved a creative structure of information analysis and expression based on POPF to improve the understanding of human facial motion and emotion
Relief of buttock claudication by percutaneous recanalization of an occluded superior gluteal artery
No full textLong-term effects of the home literacy environment on reading development: Familial risk for dyslexia as a moderator
No full textThis study aimed to gain better understanding of the associations between literacy activities at home and long-term language and literacy development. We extended the home literacy environment (HLE) model of Senechal and LeFevre (Child Development [2002], Vol. 73, pp. 445-460) by including repeated assessments of shared reading, oral language, and reading comprehension development, including examination of familial risk for dyslexia as a moderator, and following development over time from ages 2 to 15 years. Of the 198 Finnish participants, 106 have familial risk for dyslexia due to parental dyslexia. Our path models include development in vocabulary (2-5.5 years), emerging literacy (5.5 years), reading fluency (8 and 9 years), and reading comprehension (8, 9, and 15 years) as well as shared book reading with parents (2, 4, 5, 8, and 9 years), teaching literacy at home (4.5 years), and reading motivation (8-9 years). The results supported the HLE model in that teaching literacy at home predicted stronger emerging literacy skills, whereas shared book reading predicted vocabulary development and reading motivation. Both emerging literacy and vocabulary predicted reading development. Familial risk for dyslexia was a significant moderator regarding several paths; vocabulary, reading fluency, and shared reading were stronger predictors of reading comprehension among children with familial risk for dyslexia, whereas reading motivation was a stronger predictor of reading comprehension among adolescents with no familial risk. The findings underline the importance of shared reading and suggest a long-standing impact of shared reading on reading development both directly and through oral language development and reading motivation. (c) 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/ licenses/by/4.0/)
Two and three-dimensional shoreline behaviour at a MESO-MACROTIDAL barred beach
No full textThe present work investigates cross-shore shoreline migration as well as its alongshore variability (with deformation) on timescales of days to years using 6 years of time-averaged video images. The variability of the shoreline is estimated through empirical statistical methods with comprehensive reference to three scales of variability. At the meso-to macro-tidal barred Biscarrosse beach, shoreline responds in decreasing order at seasonal (winter/summer cycles, 52%), event (storms, 28%) and inter-annual scales. Whereas seasonal evolution is dominated by wave climate modulation, short-term evolution is influenced by tidal range and surf-zone sandbar characteristics. The influence of tide range and sandbars increases when timescale decreases. This is even more the case for the alongshore deformation of the shoreline which is dominated by short-term evolution. An EOF analysis reveals that the first mode of shoreline change time series is associated with cross-shore migration and explains 58% of the shoreline variability. The rest of the modes are associated to deformation which explain 42% of shoreline variabilityThe first author is co-funded by SCAC (French
embassy in Ghana) and ARTS-IRD programs. Authors acknowledge the
Region Aquitaine for financially supporting the installation of the video
system at Biscarrosse. This research has received support from French
grant through ANR COASTVAR: ANR-14-ASTR-0019. RR is supported by the AXA Research fund and the Deltares Harbour, Coastal and
Offshore Engineering Research Programme ‘Bouwen aan de Kust’. BB
is supported by French BAgence Nationale de la Recherche^ through
project CHIPO (ANR-14-ASTR-0004-01
