1,721,397 research outputs found
Patent evaluation of US2019338018 (A1) 2019-11-07 (antibody fragments for the treatment of biofilm-related disorders)
No full textIntroduction: To date, microbial infections are also difficult to eradicate due to the increasing capability of bacteria to form a biofilm. In the era of antibiotic resistance, antibody-based approaches represent great promise in curing infective pathogens. The authors of US2019338018 patent propose a method for the treatment of biofilm-related disorders by using specific antibody fragments. Areas covered: The US2019338018 patent reports antibody fragments, pharmaceutical composition that contains it, and their application for the treatment of biofilm-linked disorders. Proof concept and preclinical results show that mAb mIhfB4NTHI Fab caused robust eradication of the biofilm in the middle ear lumen of chinchillas affected by Hemophilus influenzae infection. Expert opinion: Fab fragments of the US2019338018 patent are new in a general concept to treat bacterial biofilms and biofilm-linked disorders. However, pre-clinical data are only shown for the treatment with Fab fragments of infections caused by H. influenzae in the middle ear of chinchillas. There are no clinical trials that demonstrate that the treatment with Fab fragments may induce a disruption of biofilm produced by H. influenzae or other pathogens and an anti-inflammatory response in infected patients
Analysis codes for the paper Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51.
No full textThis is the code used for analyising data of Lõoke, M., Marinelli, L., Guérineau, C., Agrillo, C., & Mongillo, P. (2022). Dogs (Canis lupus familiaris) are susceptible to the Kanizsa’s triangle illusion. Animal Cognition, 25(1), 43-51 in R
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Women’s Studies in Cina
No full textPartendo dall’osservazione del lavoro svolto da alcuni intellettuali cinesi tra la fine del XIX secolo e gli inizi del XX e degli sforzi compiuti negli ultimi decenni da attiviste e studiose legate alla Federazione delle donne cinesi, l’obiettivo che, attraverso questo intervento, ci si propone di raggiungere è illustrare in linee generali le origini e lo sviluppo nella Repubblica Popolare Cinese dei Women’s Studies come disciplina accademica. Ad un’introduzione storica, politica e sociale dei fattori che hanno contribuito alla nascita dei Women’s Studies, segue un elenco delle caratteristiche e questioni sorte all’interno di questa disciplina nel corso degli anni e come certe peculiarità negli anni si siano evolute in un’interazione tra marxismo e femminismo divenendo poi base teorica degli attuali studi sulle donne in Cina
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Szymborska. Un alfabeto del mondo. Ventuno saggi per ventuno poesie della grande scrittrice premio Nobel.
No full textAttraverso un lavoro collettivo e in un approccio originale, pur distinguibile in apporti individuali, lo studio in questione esamina e interpreta, a partire da nuclei tematici significativi, lo sguardo sul mondo e sul suo senso della poetessa premio Nobel per il 1996
Art. 3. Commissione per la vigilanza ed il controllo sul doping e per la tutela della salute nelle attività sportive
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