12,131 research outputs found
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba
No full textArchaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly to dsDNA (double-stranded DNA) than to either ssDNA (single-stranded DNA) or RNA. The Alba protein is dimeric in solution, and forms distinct ordered complexes with DNA that have been visualized by electron microscopy studies; these studies suggest that, on binding dsDNA, the protein forms extended helical protein fibres. An end-to-end association of consecutive Alba dimers is suggested by the presence of a dimer-dimer interface in crystal structures of Alba from several species, and by the strong conservation of the interface residues, centred on Are and Phe(60). In the present study we map perturbation of the polypeptide backbone of Alba upon binding to DNA and RNA by NMR, and demonstrate the central role of Phe(60) in forming the dimer dimer interface. Site-directed spin labelling and pulsed ESR are used to confirm that an end-to-end, dimer dimer interaction forms in the presence of dsDNA.Peer reviewe
Alba
No full text“Alba,” by Samuel Beckett. In: Janvier, L. Beckett par lui même. Paris Éditions du Seuil, 1969, p. 43. Translated by Maria Helena Kopschitz.“Alba,” by Samuel Beckett. In: Janvier, L. Beckett par lui même. Paris Éditions du Seuil, 1969, p. 43. Translated by Maria Helena Kopschitz
Un ricordo di Alba Maria Orselli (1934-2022)
No full textProfilo biografico di Alba Maria Orselli, studiosa di fama internazionale, già ordinaria di Storia del cristianesimo presso l'Università di Bologna
First person – Alba Delrio-Lorenzo
No full textFirst Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Alba Delrio-Lorenzo is first author on ‘Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila’, published in JCS. Alba is a PhD student in the lab of Javier García-Sancho and María Teresa Alonso at the Instituto de Biología y Genética Molecular (IBGM), University of Valladolid, Spain, investigating the molecular mechanisms implicated in aging, particularly muscle aging.Peer reviewe
Libri e lettori (tra autori e personaggi). Studi in onore di Mariolina Bertini
No full textUn volume che, parlando proprio di libri e di letture, rispecchia le scelte e le passioni di una grande studiosa come Mariolina Bertini. Mariolina Bertini si è occupata di letteratura e cultura nel senso più ampio del termine integrando lo studio della letteratura francese, che ha insegnato per decenni all’Università di Parma, con una costante attenzione verso altre letterature, e senza distinzione di genere. Basterebbero gli studi su Balzac e Proust, le edizioni di Stendhal, Flaubert o ancora di Proust e Balzac, le introduzioni a Dumas e Colette, e gli articoli su altri autori e temi a delinearne il profilo di studiosa che ha completato con una complementare, e intensa, attività militante
Alba Fucens
No full textN el grande progetto dell'Atlante archeologico è stata inserita una sintesi delle evidenze archeologiche di Alba Fucens
11. BLOQUE II Metodología: "Aprende haciendo", aplicada al área de Construcción Arquitectónica | Mª Isabel Alba Dorado; Carmen Mª Muñoz González; Cristina Pérez. E.T.S. Arquitectura Universidad de Málaga
No full textPresentació de la ponència a càrrec de Maria Isabel Alba Dorado; Carmen Maria Muñoz González i Cristina Pérez de la Escuela Técnica Superior de Arquitectura de Málag
Virées littéraires dans les récits de voyage de Jean-Claude Charles
No full textC'est Jean-Claude Charles lecteur que nous avons choisi de traquer dans ces pages. Nous l'avons suivi au cours de ses déplacements dans les différents continents qu'il arpente. Ses voyages sont l'occasion pour l'écrivain de solliciter des auteurs et des oeuvres qui habitent les territoires parcourus. Les récits proposent un intertexte très riche, nous nous proposons de limiter notre enquete, quant aux écrivains que Charles convoque, à l'espace étasunien. Nous essaierons de montrer comment Charles procède, dans la mise en forme de ces récits, à un double voyage, spatial et littéraire et comments ces deux voyages s'autoalimentent et s'expliquent tour à tour
11. BLOQUE II Metodología: "Aprende haciendo", aplicada al área de Construcción Arquitectónica | Mª Isabel Alba Dorado; Carmen Mª Muñoz González; Cristina Pérez. E.T.S. Arquitectura Universidad de Málaga
No full textPresentació de la ponència a càrrec de Maria Isabel Alba Dorado; Carmen Maria Muñoz González i Cristina Pérez de la Escuela Técnica Superior de Arquitectura de Málag
MÚSICA AMBIENTAL Y RUIDO DE COLOR COMO HERRAMIENTAS PARA MEJORAR LA CONCENTRACIÓN Y LA CREATIVIDAD EN EL AULA
No full textBlanco Parrondo, Alba Maria; director de proyecto: Colomer Sánchez, Ana2022-2023Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de IdiomasFacultad de Ciencias de la Educació
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