506 research outputs found

    Susie and John Fulton

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    The author discusses the life of Susie and John Fulton and the challenges they faced in establishing the first church school and constructing the first mission ship in Fiji as Adventist missionaries

    Travelling with Susie King Taylor

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    Susie King Taylorââ¬â¢s 1902 memoir of her Civil War experiences, Reminiscences of My Life in Camp, comprises a complex document testifying to the contest over the meaning of the Civil War in historical memory as well as the struggle of freed people, and black women in particular, to insert themselves into public dialogues as authorized subjects. Viewing Taylorââ¬â¢s narrative, the positioning of its author and the changing conditions of its reception, through the lens of black womanist theory and travel literature criticism presents an opportunity to consider the nature of knowledge in a way that resists dichotomizing authenticity and objectivity, or experience and interpretation

    A Beautiful Shame : The Anti-Monuments of Susie Ganch

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    In the article, the author features fourth-generation jeweler Susie Ganch and her environmental activism as reflected in her works. Also cited are Ganch's use of materials that decompose and can be reused in making jewelry, the humor and beauty of Ganch's art, and the other materials she uses like plastic bags and soda bottles

    A Beautiful Shame : The Anti-Monuments of Susie Ganch

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    In the article, the author features fourth-generation jeweler Susie Ganch and her environmental activism as reflected in her works. Also cited are Ganch's use of materials that decompose and can be reused in making jewelry, the humor and beauty of Ganch's art, and the other materials she uses like plastic bags and soda bottles

    Frank Arruda Interview

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    Susie Van Kirk\u27s notes from her interview with Frank Arruda, including (but not limited to) the following: Frank and Irene Arruda live where Bayview runs into Pyror on Humboldt Hill. Frank has the house built about ten years ago, but had owned the lots for many years before. He was born 22 Oct. 1930 Joseph Arruda, Sr. and Maria Joseph was born in Conn. to parents who immigrated from the Azores. Maria was born in the Azores and came to this country with her parents…. Their first house was constructed in [1949]; it was located in line with garage to the south. Photographs show the house under construction with the barn (apartments) and adjoining house in the background. It faced west. Frank and Irene lived there about seven years when they moved to Bayside…. He worked for Holmes Eureka for seven years, then moved to Concord where he worked construction for 30 years. They moved back to Humboldt County in 1991/2 and later built their present house. Before Joe and Maria moved to the Bungalow, they lived behind the Woolen mills. Joe worked at Nilson\u27s for 30 years. After the State bought their property, he purchased the motel, now known as Chinn\u27s, and he and Maria lived there, until they sold it to the Chinn family

    Fine-Mapping the Results From Genome-Wide Association Studies of Primary Biliary Cholangitis Using Susie and h2-D2

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    \ua9 2024 The Author(s). Genetic Epidemiology published by Wiley Periodicals LLC. The main goal of fine-mapping is the identification of relevant genetic variants that have a causal effect on some trait of interest, such as the presence of a disease. From a statistical point of view, fine mapping can be seen as a variable selection problem. Fine-mapping methods are often challenging to apply because of the presence of linkage disequilibrium (LD), that is, regions of the genome where the variants interrogated have high correlation. Several methods have been proposed to address this issue. Here we explore the ‘Sum of Single Effects’ (SuSiE) method, applied to real data (summary statistics) from a genome-wide meta-analysis of the autoimmune liver disease primary biliary cholangitis (PBC). Fine-mapping in this data set was previously performed using the FINEMAP program; we compare these previous results with those obtained from SuSiE, which provides an arguably more convenient and principled way of generating ‘credible sets’, that is set of predictors that are correlated with the response variable. This allows us to appropriately acknowledge the uncertainty when selecting the causal effects for the trait. We focus on the results from SuSiE-RSS, which fits the SuSiE model to summary statistics, such as z-scores, along with a correlation matrix. We also compare the SuSiE results to those obtained using a more recently developed method, h2-D2, which uses the same inputs. Overall, we find the results from SuSiE-RSS and, to a lesser extent, h2-D2, to be quite concordant with those previously obtained using FINEMAP. The resulting genes and biological pathways implicated are therefore also similar to those previously obtained, providing valuable confirmation of these previously reported results. Detailed examination of the credible sets identified suggests that, although for the majority of the loci (33 out of 56) the results from SuSiE-RSS seem most plausible, there are some loci (5 out of 56 loci) where the results from h2-D2 seem more compelling. Computer simulations suggest that, overall, SuSiE-RSS generally has slightly higher power, better precision, and better ability to identify the true number of causal variants in a region than h2-D2, although there are some scenarios where the power of h2-D2 is higher. Thus, in real data analysis, the use of complementary approaches such as both SuSiE and h2-D2 is potentially warranted

    Myself and Susie Malone

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    A couple agree to marry on a sailing trip.https://egrove.olemiss.edu/kgbsides_uk/2500/thumbnail.jp
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