1,721,242 research outputs found
Risk-reducing surgery in BRCA 1/2 mutation carries: a point of view
The work aspires to provide a reliable evaluation of the effect of risk-reducing surgery, both salpingoophorectomy (RRSO) and bilateral mastectomy (BRRM), to reduce long-term onset of ovarian cancer OC and/or BC in BRCA 1/2 mutation carries
Rucaparib Maintenance in Upfront Ovarian Cancer: The Long-Lasting Challenge of Predicting Response to Poly (ADP-ribose) Polymerase Inhibitors
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Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
From the tailoring of adjuvant treatment to the tailoring of pelvic and aortic lymphadenectomy in stage i endometrial cancer
[No abstract available]ABSTRACT
Background. Ovarian cancers have been recently categorized
into types I and II according to a dualistic model of
tumorigenesis. Data on the correlation between this classification
and clinical outcome are still scarce and controversial.
Methods. A retrospective analysis of patients with ovarian
cancer treated from 1998 to 2013 and operated by the same
surgeon was conducted. Patients were classified into two
groups: type I (125 patients), including low-grade serous,
mucinous, endometrioid, and clear cell tumors; and type II
(286 patients), including high-grade serous tumors, unspecified
adenocarcinomas, and undifferentiated carcinomas.
Results. Type II patients had a significantly higher incidence
of advanced disease than type I (88.4 vs. 65.6 %,
P = 0.0001) and required more aggressive surgical procedures.
Rates of optimal tumor debulking were almost
similar between groups (92.6 vs. 91.7 %, type I vs. II,
P = NS). After a median follow-up of 41 months, 207
patients (50.4 %) were alive and 204 (49.6 %) were dead;
79 type I patients (63.8 %) and 237 type II patients
(82.7 %) experienced relapse (P = 0.02). Progression-free
survival was significantly different between groups:
25 months for type I vs. 17 months for type II (P = 0.023).
Overall survival was not significantly different between
groups, with a median overall survival of 75 months for
type I vs. 62 months for type II (P = 0.116).
Conclusions. The dualistic histotype-based classification
into types I and II of ovarian cancer does not seem to
correlate with prognosis. Different molecular
characteristics of type I and II tumors may have therapeutic
implications and should be deeply investigated
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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