10 research outputs found
TOŻSAMOŚC NARODOWA W POLITYCE LTURALNEJ UNII EUROPEJSKIEJ (Національна ідентичність у культурній політиці Європейського Союзу)(National identity in cultural politics of European Union)
No full textДослідження має на меті здійснення аналізу питань,
пов’язаних із юридичними основами визнання національної
ідентичності в контексті культурної політики Європейського
Союзу. Авторка розглядає питання, пов’язані із визначенням
національної
ідентичності.
Намагається
довести,
що
Європейський
Союз
шанує
національну
ідентичність
держав-членів.
Авторка
висловлює
тезу,
що
дільність
Союзу
мотивується
піклуванням
про
збереження
ідентичності
окремих
народів,
тобто
їх
культури,
традиції,
релігії,
мови
в
контексті європейської територіальної спільноти (The elaboration is to analyse questions related with legal
basis of respecting national identities in connection with cultural
politics of the European Union. The author discusses problems
related with defining national identity and tries to prove that the
European Union respects national identity of Member States.
The author puts a thesis that operations of the community are
motivated by sustaining the separateness of identity of separate
nations such as culture, tradition, religion within the territory of
the European community
Stages of development of smart cities
No full textMiasta typu smart są efektem rozwoju technik innowacyjnych i całego sektora badań w zakresie zaawansowanych technologii. Liczne globalne firmy są zainteresowane sprzedażą swoich produktów, które są adresowane i przystosowywane do rozwiązań miejskich. Obserwując rozwój miast inteligentnych wyróżnić można rozmaite etapy wprowadzania produktów zaawansowanych technologicznie do codziennego życia miasta, a z czasem także do kreacji rożnej wielkości założeń urbanistycznych
a nawet całych miast. Wprowadzanie tych produktów związane jest także z prowadzonymi badaniami społeczności miejskich i ich adaptacji do przyjmowania coraz nowszych rozwiązać.
W artykule zostanie przedstawionych, wyróżnionych przez autorkę sześć etapów rozwoju miast typu smart popartych przykładami głównie z terenu Europy, oraz ich ilustracjami.Smart cities are the result of the development of innovative techniques and the entire advanced technology research sector. Numerous global companies are interested in selling their products, which are addressed and adapted to urban solutions. By observing the development of smart cities, you can distinguish the various stages of introducing technologically advanced products to the everyday life of the city, and over time also the creation of different sizes of urban assumptions and even cities. The introduction of these products is also related to ongoing research in urban communities and their adaptation to take more and newer fix. The paper will be presented, distinguished by the author of six stages in the development of smart cities supported by examples mainly from Europe, and their illustrations
Mieczysław Jastrun w Łodzi 1931–1939
No full textThe paper discusses the inter-war Łódź stage in the biography and work of Mieczysław Jastrun, which forms a part of a broader first period of the writer’s activities (1923–1941). The author of the text, based on source materials and historical documents, reconstructs the sources of the contemporary world-view of Jastrun, characterises philosophical inspirations of the poet and the feeling of threat by fascism (short story “Civitas Diaboli”), as well as the moment of his left-wing ideological turn, including consequences of Marxist reflections. The paper also focuses on the contemporary social relations of the author of Dzieje nieostygłe [History Is Cooling Down], presents Jastrun’s critical opinion of the Łódź literary milieu and some of its initiatives (e.g. the Wymiary [Dimensions] magazine), as well as sketches the image of Łódź as a juggernaut-city of the 1930s, manifested in the poems and the prose of the writer, and combines it with the contemporary personal stance of Jastrun (professional work, marriage to Krystyna Bilska, friendship with painter Karol Hiller)
DYSONTOGENESIS AND REDUCTION OF CHILDREN\u27S GAME: ANALYSIS, CONSEQUENCES, WAYS TO SOLVE PROBLEMS
No full textThe research focuses on the philosophical aspects of children\u27s play. The aim of the study is to analyze modern approaches to the classification and development of preschoolers` play activities, the negative phenomena of dysontogenesis and reduction of play. The authors analyzed the results of a survey of undergraduate students in specialty Preschool Education and their relatives about children\u27s memories of the play, game situations and the impact of play competence (or lack of it) on adult life.Basic research methods are interview, surveys, statistical analysis.The main results of the study give grounds to claim that play is not the only leading activity of a senior preschooler. Even accepting the concept of "leading" and "non-leading" activities, it turns out that children\u27s experimentation during preschool takes no less "leading" position than play. This fact radically changes the perception of conditions, goals and values in the organization of children\u27s lives.The author\u27s team proved that the dysontogenesis of play and non-acceptance of children\u27s experimentation in preschool age leads to further distortion of the trajectory of development. The author\u27s interpretation of the terms "play reduction", "play dysontogenesis", "amplification" and "simplification" of children\u27s play is proposed.
Programación fetal en el desempeño productivo del ganado de carne
No full textGráficosLa salud y el desarrollo postnatal pueden verse influenciados por los eventos que
ocurren en el útero, este concepto dio origen a lo que hoy en día se reconoce como
programación fetal. Esta reconoce que estímulos durante momentos críticos de la
gestación incluida la nutrición, alteran la trayectoria de desarrollo del feto (Du et al.,
2015), produciendo cambios permanentes en la estructura y función del organismo
en desarrollo, con el resultado de efectos persistentes que pueden observarse en
las siguientes generaciones. La programación fetal esta mediada por alteraciones
estables y heredables de la expresión génica a través de modificaciones
epigenéticas. Investigaciones en el campo de la producción animal han evidenciado
que pequeñas diferencias en la nutrición durante la gestación pueden alterar la
eficiencia de la producción de crías de por vida. Por lo tanto, el potencial para la
programación fetal se debe considerar al determinar las estrategias nutricionales
durante la gestación. Por este motivo se recopila información actualizada sobre los
impactos de la nutrición materna sobre el desarrollo fetal en el ganado de carne y el
rendimiento productivo en edad adulta.The concept that health and postnatal development can be influenced by events that
occur in the womb, gave rise to what is nowadays recognized as fetal programming.
This recognizes that stimuli during critical moments of pregnancy including nutrition,
alter the development trajectory of the fetus (Du et al., 2015), producing permanent
changes in the structure and function of the developing organism, with the result of
persistent effects that can be observed in the following generations. Fetal
programming is mediated by stable and inheritable alterations of gene expression
through epigenetic modifications. Research in the field of animal production has
shown that small differences in nutrition during pregnancy can alter the efficiency of
the production of young for life. Therefore, the potential for fetal programming should
be considered when determining nutritional strategies during pregnancy. For this
reason, updated information is collect on the challenges of maternal nutrition on fetal
development in beef cattle and productive performance adult life.Resumen. -- Abstract. -- Objetivos. -- Objetivo general. -- Objetivos específicos. -- Introducción. -- Justificación. -- Estado del arte. -- Hipótesis de Barker. -- Programación fetal - programación del desarrollo. -- Concepto. -- Modelos animales en la programación del desarrollo fetal. -- Impacto de la nutrición en la programación del Desarrollo fetal. -- Nutrición materna. -- Factores que influyen en la necesidad y partición de nutrientes. -- Mal nutrición materna. -- Programación del desarrollo placentario. -- Placentación. -- Circulación placentaria, crecimiento y desarrollo. -- Nutrición materna en el desarrollo y función placentaria. -- Nutrición materna en la programación del desarrollo fetal. -- Crecimiento fetal. -- Nutrición materna en el desarrollo del tracto gastrointestinal del feto. -- Epigenética. -- Concepto. -- Procesos epigenéticos. -- Mecanismos epigenéticos. -- Nutrición materna en los mecanismos epigenéticos. -- Nutrición materna en la programación fetal del musculo esquelético y tejido adiposo. -- Importancia de la programación fetal en el músculo esquelético, tejido adiposo y tejido conectivo. -- Programación fetal del musculo esquelético. -- Programación fetal del tejido adiposo y conectivo. -- Impacto de la programación fetal en la función reproductiva. -- Desarrollo gonadal. -- Programación fetal y rendimiento postnatal de las crías. -- Impacto de la programación fetal en el desarrollo postnatal del tejido musculo esquelético. -- Impacto de la nutrición materna en el desempeño reproductivo de la Descendencia. -- Implicaciones económicas. -- Análisis y discusión. -- Conclusiones. -- Recomendaciones. -- Bibliografía.PregradoMedico(a) Veterinario(a) ZootecnistaMedicina Veterinaria y Zootecni
Plane of nutrition and FSH-induced superovulation affect the expression of steroid hormone receptors and growth factors in caruncular tissue of non-pregnant sheep.
No full textImplantation is a critical step in the establishment of pregnancy and an important part of embryo-maternal contact. Uterine receptivity can be affected by changes in body condition and the maternal endocrine milieu, including those caused by the use of exogenous gonadotropins in controlled ovarian hyperstimulation to induce the development of multiple follicles. This study demonstrates the effects of FSH-mediated ovarian hyperstimulation on the caruncles of ewes under various feeding regimes. Sheep were classified into 3 categories: control fed (CF), overfed (OF), or underfed (UF). In each group, animals were superovulated with FSH or injected with a saline solution (non-treated control). Uterine caruncles were collected at the early (d 5) and mid-luteal phase (d 10) of the estrous cycle. The transcript levels of steroid hormone receptors (ESR1, ESR2, PGR) and growth factors (IGF1, IGF2, VEGFA) were investigated and their expression localized by immunohistochemical staining. As for the main findings, day of the estrous cycle affected expression of ESR1, IGF1 and IGF2, but not of ESR2, PGR and VEGFA; both feeding and superovulation had modulatory effects, with feeding (UF/OF) stimulating expression of all genes studied, and superovulation altering expression of some genes, eg IGF1, PGR and ESR1 and ESR2, in CF animals. Similarly, feeding (UF/OF) altered responsiveness to superovulation for PGR on d 5 and ESR1/ESR2 on d 5 and/or 10. Our data emphasize possible effects of dietary and/or hormonal stimuli on uterine physiology, which may affect pregnancy outcomes by disrupting uterine functionality. (c) 2021 The Author(s). Published by Elsevier Inc. This is an open access article under the CC BY license ( http://creativecommons.org/licenses/by/4.0/
Intraoperative transfusion practices and perioperative outcome in the European elderly: A secondary analysis of the observational ETPOS study
No full textThe demographic development suggests a dramatic growth in the number of elderly patients undergoing surgery in Europe. Most red blood cell transfusions (RBCT) are administered to older people, but little is known about perioperative transfusion practices in this population. In this secondary analysis of the prospective observational multicentre European Transfusion Practice and Outcome Study (ETPOS), we specifically evaluated intraoperative transfusion practices and the related outcomes of 3149 patients aged 65 years and older. Enrolled patients underwent elective surgery in 123 European hospitals, received at least one RBCT intraoperatively and were followed up for 30 days maximum. The mean haemoglobin value at the beginning of surgery was 108 (21) g/l, 84 (15) g/l before transfusion and 101 (16) g/l at the end of surgery. A median of 2 [1–2] units of RBCT were administered. Mostly, more than one transfusion trigger was present, with physiological triggers being preeminent. We revealed a descriptive association between each intraoperatively administered RBCT and mortality and discharge respectively, within the first 10 postoperative days but not thereafter. In our unadjusted model the hazard ratio (HR) for mortality was 1.11 (95% CI: 1.08–1.15) and the HR for discharge was 0.78 (95% CI: 0.74–0.83). After adjustment for several variables, such as age, preoperative haemoglobin and blood loss, the HR for mortality was 1.10 (95% CI: 1.05–1.15) and HR for discharge was 0.82 (95% CI: 0.78–0.87). Preoperative anaemia in European elderly surgical patients is undertreated. Various triggers seem to support the decision for RBCT. A closer monitoring of elderly patients receiving intraoperative RBCT for the first 10 postoperative days might be justifiable. Further research on the causal relationship between RBCT and outcomes and on optimal transfusion strategies in the elderly population is warranted. A thorough analysis of different time periods within the first 30 postoperative days is recommended
Intraoperative transfusion practices in Europe
No full text© 2016 The Author. Published by Oxford University Press on behalf of the British Journal of Anaesthesia.Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold
Intraoperative transfusion practices in Europe
No full text\ua9 2016 The Author. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. Background: Transfusion of allogeneic blood influences outcome after surgery. Despite widespread availability of transfusion guidelines, transfusion practices might vary among physicians, departments, hospitals and countries. Our aim was to determine the amount of packed red blood cells (pRBC) and blood products transfused intraoperatively, and to describe factors determining transfusion throughout Europe. Methods: We did a prospective observational cohort study enrolling 5803 patients in 126 European centres that received at least one pRBC unit intraoperatively, during a continuous three month period in 2013. Results: The overall intraoperative transfusion rate was 1.8%; 59% of transfusions were at least partially initiated as a result of a physiological transfusion trigger- mostly because of hypotension (55.4%) and/or tachycardia (30.7%). Haemoglobin (Hb)- based transfusion trigger alone initiated only 8.5% of transfusions. The Hb concentration [mean (sd)] just before transfusion was 8.1 (1.7) g dl-1 and increased to 9.8 (1.8) g dl-1 after transfusion. The mean number of intraoperatively transfused pRBC units was 2.5 (2.7) units (median 2). Conclusions: Although European Society of Anaesthesiology transfusion guidelines are moderately implemented in Europe with respect to Hb threshold for transfusion (7-9 g dl-1), there is still an urgent need for further educational efforts that focus on the number of pRBC units to be transfused at this threshold
Intraoperative transfusion practices and perioperative outcome in the European elderly: A secondary analysis of the observational ETPOS study.
No full textThe demographic development suggests a dramatic growth in the number of elderly patients undergoing surgery in Europe. Most red blood cell transfusions (RBCT) are administered to older people, but little is known about perioperative transfusion practices in this population. In this secondary analysis of the prospective observational multicentre European Transfusion Practice and Outcome Study (ETPOS), we specifically evaluated intraoperative transfusion practices and the related outcomes of 3149 patients aged 65 years and older. Enrolled patients underwent elective surgery in 123 European hospitals, received at least one RBCT intraoperatively and were followed up for 30 days maximum. The mean haemoglobin value at the beginning of surgery was 108 (21) g/l, 84 (15) g/l before transfusion and 101 (16) g/l at the end of surgery. A median of 2 [1-2] units of RBCT were administered. Mostly, more than one transfusion trigger was present, with physiological triggers being preeminent. We revealed a descriptive association between each intraoperatively administered RBCT and mortality and discharge respectively, within the first 10 postoperative days but not thereafter. In our unadjusted model the hazard ratio (HR) for mortality was 1.11 (95% CI: 1.08-1.15) and the HR for discharge was 0.78 (95% CI: 0.74-0.83). After adjustment for several variables, such as age, preoperative haemoglobin and blood loss, the HR for mortality was 1.10 (95% CI: 1.05-1.15) and HR for discharge was 0.82 (95% CI: 0.78-0.87). Pre-operative anaemia in European elderly surgical patients is undertreated. Various triggers seem to support the decision for RBCT. A closer monitoring of elderly patients receiving intraoperative RBCT for the first 10 postoperative days might be justifiable. Further research on the causal relationship between RBCT and outcomes and on optimal transfusion strategies in the elderly population is warranted. A thorough analysis of different time periods within the first 30 postoperative days is recommended
