1,721,039 research outputs found

    Saluti

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    Nella tradizione scientifica e culturale dell’Università Cattolica il confronto con l’opera di Dante ha costituito fin dall’inizio un nodo tematico centrale. Si ricordano al proposito i primi contributi della Rivista di Filosofia Neo-Scolastica e l’attenzione dedicata a Dante da molti docenti.In the scientific and cultural tradition of the Catholic University, the comparison with Dante’s work has been a central thematic node from the outset. In this regard, we recall the first contributions of the Rivista di Filosofia Neo-Scolastica and the attention dedicated to Dante by many scholars

    Presentación a "Pensar para el nuevo siglo. Giambattista Vico y la cultura europea"

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    Vico nel contesto della cultura europea

    Prefazione

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    Il pensiero di Cicerone, sul solco dell'accademia scettica, costruisce le sue argomentazioni secondo una logica "retorica" e non "scientifica

    Real-world Evidence on Oral Semaglutide for the Management of Type 2 Diabetes. A Narrative Review for Clinical Practice

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    Purpose: Oral semaglutide is the first oral glucagon-like peptide-1 receptor agonist (GLP-1RA) available for type 2 diabetes mellitus (T2DM) management, whose effectiveness and tolerability have extensively been demonstrated in the PIONEER clinical trial program. Nevertheless, data from real-world are crucial to evaluate treatment performance under routine care. The aim of this narrative review is to summarize available evidence regarding real-world utilization patterns of oral semaglutide, and discuss efficacy, safety, and dosing regimen data in routine scenarios. Methods: We searched PubMed for real-world studies evaluating oral semaglutide up to August 2024, and specific search terms were: “oral semaglutide,” and “real-world studies” or “observational studies” or “retrospective studies”. Findings: 19 real-world studies were included in the narrative review. In real-world settings, oral semaglutide provided significant glycemic (median HbA1c reduction at 6 months of 1%) and weight (median body weight reduction of 2 to 3 kg) benefits across the spectrum of T2DM, aligning with pre-clinical evidence from the PIONEER program. No new tolerability and safety issue has emerged from oral semaglutide administration in routine clinical practice. Implications: Oral semaglutide constitutes an effective and safe option for T2DM management, and its increased acceptance has the potential to favor the early introduction of GLP-1RAs along the disease course. Nevertheless, continuous evaluation of real-world data is critical to better define the optimal positioning of oral semaglutide along T2DM trajectory and fully exploit its potential in everyday clinical practice

    Kant e la metafisica critica

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    Kant identifies the Enlightenment as the emergence of humanity from a state of minority, achieved through the courage to use reason. Criticism serves as the instrument to define the limits and legitimate uses of reason, replacing pre-established norms and authorities with this autonomous faculty of the subject. This allows for the possibility of a metaphysics of nature and morality through the structures of such faculty. Additionally, in the Critique of Judgment, the connection between nature and freedom is mediated by reflective judgment, which introduces a teleological orientation into Kantian reflection

    Introduzione

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    Introduzione a raccolta di "Studi in memoria di Ernesto Grassi

    Poesia e non poesia L'estetica crociana e la Commedia

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    L'estetica di Benedetto Croce e la Commedia di Dant

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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