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Rugao Mao shi cong shu /
No full textDouble leaves, oriental style, in case.Blockprint.v. 1 Chang chao min xian sheng nian pu -- v. 2-5 Chaomin shi ji : 6 juan / Mao Xiang zhuan -- v. 6 Fu ren ji zhu : 1 juan / Chen Jisong zhuan ; Mao Bao zhu. Zhu cuo xuan shi ji / Mao Bao. Han bi tang shi ji -- v. 7-8 Pu chao wen xuan : 4 juan -- v. 8 Ying mei an yi yu -- v. 9 Xiang li yuan ou cun. Han pi ku yin. Ji mei ren ming shi. Fan xue xiao cao. Lan Yan. Zhen cha hui chao. Xuan lu ge zhu -- v. 10 Zhen yan tang shi ji. Shen yuan shi shuo : 4 juan -- v. 11 Qian hou yuan xi yan ji shi : 2 juan. Chen kan lu -- v. 12-15 Rugao Mao shi shi lue : 14 juan -- v. 16 Xie kang le ji shi yi / Xie ling yun. Xie kang le xiao shen ji. He xie kang le shi -- v. 17-19 Xiao san wu ting wen jia ji -- v. 18 Kuan liu chi / Wang Guan-- v. 20 Zhe shi shi lu / Zhou Murun zhuan. Ren an yi gao / Zhou Yuexiu zhuan. Chuan zhong tang xue gu wen / Zhou Xingjian zhuan -- v. 21 Ou tang sheng gao / Zhou Xingyu zhuan. Dong ou cao tang ci : 2 juan / Zhou Xingyu zhuan. [?]Kuang shi zhi / Zhou Xingyi. Wai jia ji wen.Mode of access: Internet
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Expression regulation of MAO isoforms in monocytic cells in response to Th2 cytokines
No full textBackground: Th2-cytokines, such as interleukins-4 and –13 (IL-4, IL-13), have been identified as alternative stimuli of monocytes/macrophages. We have recently profiled the gene-expression pattern of IL-4-teated human peripheral monocytes and found that 15-lipoxygenase-1 (15-LOX1) and monoamine oxidase A (MAO-A) are among the five most strongly upregulated gene products in IL-4-treated cells. Transfection of monocytic cells (U937) with 15-LOX1 also induced MAO-A expression. These data suggested that 15-LOX1 products might play a role in the IL4-induced signaling cascade leading to expression of MAO-A in human monocytes. Material/Methods: To test this hypothesis we incubated wild-type and 15-LOX1-transfected U937 cells with different concentrations of either IL-4 or 15-LOX-products [13S-H(p)ODE, 15S-H(p)ETE] and quantified the expression of 15-LOX1, MAO-A, and MAO-B by activity assays and real-time RT-PCR. Results: Wild-type U937 cells express neither MAO-A nor MAO-B, but after three days of IL4 treatment, MAO-A mRNA was detected. A similar isoform-specific expression of MAO-A mRNA was observed when U937 cells were transfected with 15-LOX1 or when the cells were incubated with primary 15-LOX1 products (hydroperoxy fatty acids) or H2O2. In contrast, the corresponding hydroxy fatty acids were ineffective. Conclusions: These data indicate that increased intracellular peroxide concentrations (oxidative stress) induce MAO-A expression in monocytes/macrophages, which normally do not express the enzyme. Our findings also suggest that IL-4-induced upregulation of MAO-A expression in human peripheral monocytes may proceed via 15-LOX1-dependent and 15-LOX1-independent pathways. The biological role of MAO-A expression for monocyte function is discussed
Development of Novel Fluorine-18 Labeled PET Radioligands for Monoamine Oxidase B (MAO-B)
No full textMonoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selective and irreversible MAO-B inhibitors such as L-deprenyl and rasagiline are clinically used for the treatment of psychiatric and neurological disorders. Positron emission tomography (PET) is a noninvasive imaging technique which has been utilized to visualize the localization of MAO-B in monkey and human brain and thereby has potential for studying neurodegenerative diseases and epilepsy. This thesis deals with the synthesis and evaluation of novel fluorine-18 labeled PET radioligands for detection of MAO-B activity.
The present thesis demonstrates that nine fluorinated propargyl amines were synthesized and tested for inhibition of MAO-B. In order to label those compounds with fluorine-18 seven chloro-precursors and two sulphamidate-precursors were also synthesized by multi step organic synthesis. Radiolabeling of six chloro-precursors with fluorine-18 was accomplished by a one-step nucleophilic substitution reaction. Radiolabeling of two sulphamidate-precursors with fluorine-18 was performed in two steps, compromising a nucleophilic substitution followed by the removal of the protecting group. The incorporation yield of the fluorination reactions varied from 40- 70%. The radiochemical purity was >99% and the specific radioactivities were in a range of 190-240 GBq/μmol at the time of administration.
In vitro MAO inhibition and/or autoradiography (ARG) experiments demonstrated a high selectivity for MAO-B over MAO-A for five of the compounds namely [18F]fluorodeprenyl, [18F]fluororasagiline, [18F]fluoro-N,4-dimethyl-N-(prop-2-ynyl) pentan-2-amine, [18F]fluorodeprenyl-D2 and [18F]fluororasagiline-D2. All five compounds were examined by PET and showed a high initial brain uptake in known MAO-B rich regions in cynomolgus monkey. [18F]Fluorodeprenyl showed a kinetic behavior similar to [11C]deprenyl where its fast irreversible binding to the enzyme renders the distribution of this radioligand in tissue limited by blood flow rather than the MAO-B enzyme concentration. [18F]Fluororasagiline and [18F]fluoro-N,4-dimethyl-N-(prop-2-ynyl)pentan-2-amine showed continuous increase of the radioactivity throughout the PET measurement that might be an indication of a blood-brain barrier penetrating radiometabolite which might in turn complicate a reliable quantification. Only [18F]fluorodeprenyl-D2 and [18F]fluororasagiline-D2 showed fast wash-out from the brain and less accumulation in cortical and sub-cortical regions. Radiometabolite studies demonstrated that both deuterated analogues were more stable measured in monkey plasma when compared to the non-deuterated analogues.
These results together suggest that both [18F]fluorodeprenyl-D2 and [18F]fluororasagiline-D2 may be improved PET radioligands and potential molecular imaging biomarker candidates for PET studies in neuroinflammation and neurodegeneration, accompanied with astrocyte activation
The portrayal of women in Mao Dun's early fiction 1927-1932
No full textIt is the prevailing critical assessment of Mao Dun's early creative writing that he displays a singular insight in his portrayal of women. This thesis seeks not only to challenge this assessment by a predominantly male body of criticism but also the assumptions on which it is based, namely that an intellectual sympathy for the women’s cause necessarily implies a transcendence of the patriarchal attitudes with which society is imbued. The major short stories and novellas written between 1927 and 1932 are analysed systematically to identify Mao Dun's underlying attitudes towards women. His portrayal of women is assessed from the following perspectives:~ his autobiographical accounts of his encounters with women in his political and personal life and his deliberate association of his female comrades with his creative inspiration;- traditional Chinese perceptions of women and gender roles as these are manifested in the classical tradition;-- Mao Dun's numerous articles and essays on the women's question written during the nineteen twenties and his work in the women's section of the Party in Shanghai;- Mao Dun's attempt to reconcile his conflicting sympathies for feminism and socialism. This thesis relies for its methodology on Western feminist criticism. While the approach is maintained, in its application to the context of early twentieth century China, its eurocentrism in terms of cultural assumptions and perceptions of gender has been replaced by a definition of Chinese values. Since a fundamental prerequisite, of feminist criticism is the assessment of the writer in his/her own cultural context, a historical survey of the portrayal of women in traditional literature is provided to serve as a standard against which to measure Mao Dun’s portrayal
Mao by Mao
No full textAn autobiographical look at the life and influence of Mao Zedong, Marxist theorist, soldier, and statesman. The commentary of this film is exclusively composed of excerpts from Mao Tsê-tung's speeches and writings, published by the Red Guard during the Cultural Revolution.Narrator, Jack Belden.Title and credits in Chinese, English, and French; narration in English
Mao Zedong Thought, Nationality (Minzu), Identity, and Chinese Unity
No full textAlthough Mao Zedong (1893-1976), the long-time leader of the Communist Party of China (CPC), was the main creator of Mao Zedong Thought, he was not the only one, so references to Mao Zedong Thought may involve works other than those written by Mao. One of the many significant issues in Mao Zedong Thought is minzu, usually rendered into English as "nationality" or "nation." The term has two different meanings. One is the collectivity of ethnic groups that make up a nation-state, specifically China. The other is the individual ethnic groups, or "minority nationalities" (shaoshu minzu) within the larger nation-state. This paper will analyse how these meanings interrelate and the complexities of how the concept of "nation" operates within the Chinese state in the context of Mao Zedong Thought. The Chinese state recognizes fifty-five minority nationalities or ethnic minorities, with the process of identification being all but complete by the time Mao Zedong died in 1976. Mao Zedong was sympathetic to the notion of ethnic self-determination and respect for the cultures and languages of ethnic minorities, but only with the proviso that it did not lead to ethnic separatism. There has been a revival of ethnic identity in China since the reform period began in 1978, which accords generally with concepts found in Mao Zedong Thought. The great majority of members of ethnic minorities are happy to belong to the Chinese nation-state. There are potential and in a few cases actual contradictions between the notion of a multinational unitary nation-state and ethnically driven identities. Nevertheless, the paper's central argument is that these contradictions are not now, and need not become, so acute as to threaten the survival of a united China. Mao Zedong Thought has mostly been entirely consistent with harmonious ethnic integration.No Full Tex
Foreigners under Mao Western Lives in China, 1949-1976
No full textForeigners under Mao: Western Lives in China, 1949-1976 is a pioneering study of the Western community during the turbulent Mao era. Based largely on personal interviews, memoirs, private letters, and archives, this book 'gives a voice' to the Westerners who lived under Mao. It shows that China was not as closed to Western residents as has often been portrayed. The book examines the lives of six different groups of Westerners: 'foreign comrades' who made their home in Mao's China, twenty-two former Korean War POWs who controversially chose China ahead of repatriation, diplomats of Western countries that recognized the People's Republic, the few foreign correspondents permitted to work in China, 'foreign experts', and language students. Each of these groups led distinct lives under Mao, while sharing the experience of a highly politicized society and of official measures to isolate them from everyday China.Intro -- Contents -- Acknowledgements -- Note on transliteration -- List of Abbreviations -- Chronology of Mao's China -- Introduction: Living under Mao -- Part I: 'Foreign comrades' -- 1. Into Mao's China -- 2. Identities and roles -- 3. Interactions -- Part II: POW 'turncoats' -- 4. Choosing China -- 5. Disenchantment -- Part III: Diplomats -- 6. 'The world within' -- 7. Licensed contacts and beyond -- 8. Cold War diplomacy -- Part IV: Correspondents -- 9. 'Our life and hard times' -- 10. The web of relationships -- 11. 'Dateline-Peking' -- Part V: 'Foreign experts' -- 12. Helping China? -- 13. Personal and political dynamics -- Part VI: Students -- 14. Studying, Maoist style -- 15. Breaking down the barriers? -- Part VII: The Western community(ies) -- 16. Across divides -- 17. After Mao -- Notes -- Bibliography -- IndexForeigners under Mao: Western Lives in China, 1949-1976 is a pioneering study of the Western community during the turbulent Mao era. Based largely on personal interviews, memoirs, private letters, and archives, this book 'gives a voice' to the Westerners who lived under Mao. It shows that China was not as closed to Western residents as has often been portrayed. The book examines the lives of six different groups of Westerners: 'foreign comrades' who made their home in Mao's China, twenty-two former Korean War POWs who controversially chose China ahead of repatriation, diplomats of Western countries that recognized the People's Republic, the few foreign correspondents permitted to work in China, 'foreign experts', and language students. Each of these groups led distinct lives under Mao, while sharing the experience of a highly politicized society and of official measures to isolate them from everyday China.Description based on publisher supplied metadata and other sources.Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, YYYY. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries
Platelet monoamine oxidase activity in alcoholics with and without a family history of alcoholism
No full textA number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for alcoholism (n = 28) and a group of healthy controls (n = 21). Clinical assessments were made using the SCID II interview for psychiatric disorders, the Family History Assessment Module and the Semi-Structural Assessment of Genetics in Alcoholism, a questionnaire especially designed for genetic studies. Platelet MAO activity with and without ethanol stimulation and the percentage of MAO activity with ethanol did not differ between groups. The only significant difference was a lower inhibition of MAO activity with ethanol in alcoholics both with and without a family history compared to controls. In patients with antisocial personality traits, platelet MAO activity was also not found to be different from other alcoholics. Our findings question the hypothesis of reduced platelet MAO activity to be a possible vulnerability marker for alcoholism. Copyright (C) 2000 S. Karger AG. Basel
淮南子
No full text高誘注 ; 茅坤批評].綫裝.框19.4 x 12.8公分, 9行19字, 小字雙行同, 白口, 單魚尾, 左右雙邊, 眉端刻評.Xian zhuang.Kuang 19.4 x 12.8 gong fen, 9 hang 19 zi, xiao zi shuang xing tong, bai kou, dan yu wei, zuo you shuang bian, mei duan ke ping.Gao You zhu ; Mao Kun pi ping]
Root mechanical traits of 12 herbaceous species
No full textThis dataset contains root mechanical traits of 12 herhaceous species that were used in the publication Mao et al. OIKOS
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