1,720,966 research outputs found

    PMWS (Postweaning Multisystemic Wasting Syndrome) In Central Italy: Histopathological, Immunohistochemical and Ultrastructural Findings

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    We describe the presence of Porcine circovirus 2 (PCV-2) in thirteen pigs necropsied in Department of Biopathological Sciences and Hygiene of Animal and Alimentary Productions in Perugia. Sistemic lymphadenopathy, sometimes haemorrhagic and necrotic, spleen enlarged thymus atrophic, lungs collapse and consolidated, were the principal gross findings. The most consistent histological lesion was a moderate to severe lymphocellular depletion in lymphoid organs, syncytial giant cell formation, and intracytoplasmic inclusion bodies in macrophages. PCV-2 was immunohistochemically detected in all pigs with PMWS. Electron microscopy investigations demonstrated viral particles compatible with Porcine PCV-2

    A preliminary study on similarities and dissimilarities of Neurological Soft Signs in schizophrenic and obsessive-compulsive disorders suggests a common maldevelopmental model

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    Aim. Neurological Soft Signs (NSS) represent minor neurological signs related to non-specific cerebral alterations. They have been documented in many psychiatric disorders including schizophrenia (SCZ) and obsessive-compulsive disorder (OCD). Aim of this study was to determine and compare the incidence and severity of NSS in patients with SCZ, in patients with OCD, and healthy control subjects (HCs). Methods. Using the Neurological Evaluation Scale (NES), this study investigated NSS in 15 SCZ patients, 14 OCD patients, and 15 HCs. PANSS and Y-BOCS were used to evaluate clinical picture in both groups. Results. Patients with SCZ showed significantly higher scores compared to HCs in the NES total and each of the three NES subscales (Integrative Sensory Function, Motor Coordination, and Sequencing of Complex Motor Acts). Patients with OCD also showed significantly higher scores compared to HCs in the NES total, Motor Coordination and Sequencing of Complex Motor Acts, but not in Integrative Sensory Function. No significant differences emerged in the NES total and the various subscales scores between the two patients’ groups. Conclusions. Our results seem to confirm the presence of NSS in both SCZ and OCD. The different types of NSS presented by the two patients’ groups versus HCs further supports the findings of widespread cerebral alterations in SCZ, on the other hand, with a preferential involvement of prefrontal and frontal cortex in OCD

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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