1,721,122 research outputs found
ESR Essentials: diagnostic work-up in patients with symptomatic breast disease—practice recommendations by the European Society of Breast Imaging
No full textBreast complaints are frequent reasons for consultations in primary care or breast clinics. Breast pain, breast lumps, and nipple discharge are the most common complaints. Less common symptoms such as skin changes and axillary abnormalities also require specific diagnostic approaches. Imaging the symptomatic breast should be performed by appropriately trained breast radiologists following the best practice guidelines and quality standards. Full-field digital mammography (FFDM), digital breast tomosynthesis (DBT), and breast ultrasound (US) are the main modalities used in this primary setting. The choice depends on the patient's age and symptoms. Women younger than 30-years-old are first imaged by US, whereas women over 40-years-old usually require both FFDM or DBT and US. For women between 30-years-old and 40-years-old, the US is the modality of choice, whereas FFDM or DBT might also be performed if needed. Pregnant or lactating women with palpable lesions or nipple discharge are imaged with US as the first method; FFDM or DBT can also be performed depending on the degree of suspicion as the dose to the fetus is minimal, and shielding may even further reduce the dose. More advanced techniques such as breast magnetic resonance imaging or contrast-enhanced mammography are not indicated in this first diagnostic setting and are reserved for cases of established malignancy (local staging) or rare cases of equivocal findings not otherwise resolved or inflammatory breast cancer. Last, but not least, male breast symptoms should also be addressed with US and/or FFDM
Development of 3D patient-based super-resolution digital breast phantoms using machine learning
No full textDigital phantoms are important tools for optimization and evaluation of x-ray imaging systems, and should ideally reflect the 3D structure of human anatomy and its potential variability. In addition, they need to include a good level of detail at a high enough spatial resolution to accurately model the continuous nature of the human anatomy. A pipeline to increase the spatial resolution of patient-based digital breast phantoms that can be used for computer simulations of breast imaging is proposed. Given a tomographic breast image of finite resolution, the proposed methods can generate a phantom and increase its resolution at will, not only simply through super-sampling, but also by generating additional random glandular details to account for glandular edges and strands to compensate for those that may have not been detected in the original image due to the limited spatial resolution of the imaging system used. The proposed algorithms use supervised learning to predict the loss in glandularity due to limited resolution, and then to realistically recover this loss by learning the mapping between low and high resolution images. They were trained on high-resolution synchrotron images (detector pixel size 60 μm) reconstructed at seven voxel dimensions (60 μm– 480 μm), and applied to patient images acquired with a clinical breast CT system (detector pixel size 194 μm) to generate super-resolution phantoms (voxel sizes 68 μm). Several evaluations were made to assess the appropriateness of the developed methods, both with the synchrotron (relative prediction error 0.010 ± 0.004, recovering accuracy 0.95 ± 0.04), and with the clinical images (average glandularity error at 194 μm: 0.15% ± 0.12%). Finally, a breast radiologist assessed the realism of the developed phantoms by blindly comparing original and phantom images, resulting in not being able to distinguish the real from the phantom images. In conclusion, the proposed method can generate super-resolution phantoms from tomographic breast patient images that can be used for future computer simulations for optimization of new breast imaging technologies
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Multimodal Breast MRI Language-Image Pretraining (MLIP):An Exploration of a Breast MRI Foundation Model
No full textBreast magnetic resonance imaging (MRI) is widely recognized for its high sensitivity in detecting breast cancer. However, interpreting breast MRI scans remains a complex, time-consuming, and resource-intensive task, even for experienced radiologists. To address these challenges, artificial intelligence-based methods are increasingly being employed. In this study, we developed a multimodal breast MRI language-image pre-training (MLIP) approach as an initial exploration of a breast MRI foundation model to aid in the interpretation of scans. Two types of inferences were used to evaluate MLIP’s performance. First, MLIP could retrieve corresponding MRI cases from a dataset based on a query, achieving an area under the receiver operating characteristic curve of 0.717 for suspicious and malignant cases, 0.640 for dense breasts, and 0.601 for low background parenchymal enhancement (BPE). Second, MLIP demonstrated the ability to predict the level of disease suspicion for a given MRI case. The results suggest that MLIP has the potential to serve as a foundation model for breast MRI interpretation. Future work will focus on expanding its capabilities through various downstream tasks and integrating additional models to enhance overall performance
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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