197,100 research outputs found

    An Evaluation of Mand and Tact Assessment Procedures

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    There are many empirically validated interventions to establish vocal mands and tacts for children (e.g., Miguel, Carr, & Michael, 2002; Wallace, Iwata, & Hanley, 2006); however, the method for determining the most appropriate intervention for each individual is unclear. An assessment is one way to identify an effective intervention for a given individual. The purpose of the current study was to replicate and extend Bourret, Vollmer, & Rapp (2004) who evaluated an assessment to inform effective mand interventions for three boys with vocal mand deficits. In the first study, we replicated the full mand assessment as described by Bourret et al. and compared the full assessment to a brief mand assessment with similar procedures. Results showed that the full mand assessment and the brief mand assessment identified similar patterns of responding for all three participants. In addition, there was increased efficiency of the brief mand assessment when compared to the full mand assessment. In the second study, we extended the brief assessment from the mand to the tact to evaluate the identification of training strategies for the tact. Results of the brief tact assessment identified similar patterns of responding to the brief mand assessment for two of the three participants and a dissimilar outcome for one participant, suggesting that vocal verbal deficits may differ across verbal operants

    Hydrogenase utilization and regulation in species of methanosarcina

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    Methane producing archaea have a vital role in the global carbon cycle by facilitating the conversion of organic carbon into CO2 and methane. Species of Methanosarcina are unique among methanogens due to a versatile metabolism that allows the use of a wide range of substrates through four overlapping methanogenic pathways. Two of the pathways require H2 as a substrate, while the others can use H2 as an electron carrier via a hydrogen cycling mechanism, which was previously demonstrated for Methanosarcina barkeri. Both uses of H2 require the activity of three different hydrogenase enzymes, however, M. barkeri can also utilize an electron transport system that is independent of hydrogenase activity. In Chapter 2, the interconnected nature of H2-dependent and H2-independent metabolic pathways was investigated in a series of M. barkeri hydrogenase deletion mutants. Phenotypic analysis of these mutants, including characterization of growth, methanogenesis, and gene regulation, allowed detection of an alternative ferredoxin-dependent electron transport system that does not require the production or consumption of H2. Additionally, we found that H2-dependent inhibition of the oxidative branch of methanogenesis required active hydrogenases, and that M. barkeri was potentially able to regulate gene expression based on the redox state of coenzyme F420. In Chapter 3, I explored the regulation of hydrogenases in Methanosarcina acetivorans, a species that is incapable of metabolizing H2, yet encodes hydrogenases with high similarity to the active enzymes found in M. barkeri. Despite the lack of hydrogenase activity in its native host, I found that the Vht hydrogenase from M. acetivorans was fully active when expressed in M. barkeri. Further assessment of Vht from M. acetivorans revealed that transcript levels were diminished when compared to M. barkeri, and that the hydrogenase protein was not detectable when expressed from the native promoter. In addition to Vht regulation at the transcriptional and translational levels, I found that M. acetivorans has a mechanism of post-translational control that disallows maturation of the hydrogenase into a fully active enzyme. Finally, in Chapter 4 I summarize the significant findings of this research, and outline several projects for continued investigation of energy conservation and gene regulation in Methanosarcina.Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2019-02-05 without embargo termsThe student, Thomas Mand, accepted the attached license on 2018-10-07 at 12:27.The student, Thomas Mand, submitted this Dissertation for approval on 2018-10-07 at 12:28.This Dissertation was approved for publication on 2018-10-08 at 13:51.DSpace SAF Submission Ingestion Package generated from Vireo submission #13028 on 2019-02-05 at 11:08:10Made available in DSpace on 2019-02-06T19:32:43Z (GMT). No. of bitstreams: 3 MAND-DISSERTATION-2018.pdf: 21374424 bytes, checksum: 7fac79fa593fdebd91dcc585712e3f57 (MD5) LICENSE.txt: 4208 bytes, checksum: de4acd807553ec2fd68049ddb94c6b7c (MD5) PROQUEST_LICENSE.txt: 4554 bytes, checksum: 8083977b85454ebbd8d0b053ed4bf2b3 (MD5) Previous issue date: 2018-10-0

    Dr. Duane M. Jackson, Morehouse College, July 2011

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    This video is a conversation with Dr. Duane M. Jackson. Dr. Jackson talks about his paper, "Recall and the Serial Position Effect: The Role of Primacy and Recency on Accounting Students' Performance." Jackie Daniel, AUC Woodruff Library, is the interviewer

    The Effects of Script-Fading Procedures and Extinction Procedures on the Variability of Mand Frames Used by Young Children with Autism

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    A primary deficit seen in many children with autism, particularly those with limited verbal repertoires, is repetitive and rote verbal behavior. This type of repetitive or rote verbal behavior can be stigmatizing and may severely limit access to primary reinforcers. Therefore, it may be beneficial to attempt to increase response variability in verbal behavior demonstrated by children with autism. Previous researchers have focused their efforts on examining response variability in motor behavior or existing verbal behavior, rather than new or recently taught verbal behavior. A potentially complementary intervention for teaching new verbal interactions is the use of scripts and script fading procedures. However, the effect of scripts and script fading procedures on the response variability of verbal behavior remains unknown. Thus, the present study attempted to answer several research questions. First, we examined the effects on extinction on response variability of mand frames used by young children with autism that exhibit limited manding repertoires. Second, we examined the effects of script training on the variability of mand frames, and finally, the effects of extinction after teaching a variety of mand frames with children with autism. Results demonstrated that (a) extinction prior to any teaching was not successful in increasing response variability, (b) teaching multiple mand frames in a successive pattern did not increase response variability of mand frames for any of the participants, (c) extinction after teaching additional mand frames increased response variability for two of the three participants, and (d) a multiple script presentation intervention increased response variability of mand frames for one participant

    Éditions allemandes de Loche et de J.-J. Rousseau, Bibliothek pädagogischer Klassiker, publiée sous la direction de M. Mand chez Herm. Beyer et fils. Langensalza

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    Arvert Franck d'. Éditions allemandes de Loche et de J.-J. Rousseau, Bibliothek pädagogischer Klassiker, publiée sous la direction de M. Mand chez Herm. Beyer et fils. Langensalza. In: Revue internationale de l'enseignement, tome 11, Janvier-Juin 1886. pp. 94-95

    Éditions allemandes de Loche et de J.-J. Rousseau, Bibliothek pädagogischer Klassiker, publiée sous la direction de M. Mand chez Herm. Beyer et fils. Langensalza

    No full text
    Arvert Franck d'. Éditions allemandes de Loche et de J.-J. Rousseau, Bibliothek pädagogischer Klassiker, publiée sous la direction de M. Mand chez Herm. Beyer et fils. Langensalza. In: Revue internationale de l'enseignement, tome 11, Janvier-Juin 1886. pp. 94-95

    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States" By M. Carey.

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    "Reflections on the subject of Emigration from Europe with a view to Settlement in the United States: containing bried sketches of the moral and political character of those states. By M. Carey, member of the American philosophical, and of the American Antiquarian Society, and author of The Olive Branch, Cindiciae Hibernicae, essays on banking, on political economy, and on internal improvement. To which are now added the English editor's comments on the subject; together with Important Advice to Emigrants, and Cautions Against Impositions Practiced in the Outports

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Dr. Glendon Swarthout

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    Hosted by Roger M. Busfield, MSU Assistant Professor of Speech and Theater, Meet the Author is designed to introduce a general audience to a contemporary author and their work through in-depth interviews. This episode features a conversation between Dr. Glendon Swarthout, prolific author and English professor at MSU, and assistant professors Sam S. Baskett and Theodore B. Strandness
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