9,553 research outputs found
The effect of E. coli endotoxin on the metabolic responses of Wistar rats
No full textEscherichia coli endotoxin is a potent stimulator of IL-1 and cachectin/TNF production from macrophages. Both IL-1 and cachectin/TNF have been implicated in muscle protein loss, acute phase protein synthesis, fever, depressed serum zinc, and elevate serum corticosterone concentration. The source of mobilized amino acids during infection and inflammation is believed to come from muscle proteolysis. Data presented in this thesis clearly indicated that the relative contribution to the negative N balance by skin and bone should not be neglected. The reduction in fractional rates of protein synthesis measured by injection of flooding doses of [3H]-phenylalanine in the endotoxin was in the order of skin (abdomen) > bone > muscle. These also run parallel with the reduction of protein content. Total liver protein synthesised per day in the endotoxin-treated animals was increased. Some preparations of E. coli endotoxin (phenol and TCA extract) (ED) are hypothermic and enhanced greater reduction in food intake and body weight loss; while the butanol extracts of endotoxin (ES) caused fever, produced less anorexia and body weight loss. The reason for these differences is not clear but may be due to the production of potent shock mediator, cachectin/TNF and/or stimulation on the sympatho-adrenal nervous sytem. The latter action may be modulated by protaglandins since indomethacin prevented ED-induced hypothermia. Administration of the β-adrengeric blocker propranolol, blunted the ES-induced hyperthermia and delayed the recovery of ED-induced hypothermia. The contribution of heat from non-thermogenesis in brown adipose tissue is unimportant in the production of fever since the binding of [^3H]-GDP to BAT mitochondria in both hyperthermic and hypothermic animals did not differ from that of the saline-treated animals. The present investigation suggests the existence of the diurnal variation in the body temperature responses to endotoxin. Both ES and ED produced hypothermia. Furthermore, reversed the lighting cycles (6pm-6am) (RL) affected : serum zinc, corticosterone, except for tissue protein loss. Both ES and ED produced hypothermia in the RL-adopted rats. The production and actions of IL-1 and cachectin/TNF may be affected by dietary fatty acids concentration and composition. Feeding rats with diets either enriched with or supplemented by 30g/kg, 90g/kg and 200g/kg of hydrogenated coconut oil (HCO); or by the 9og/Kg fish oil (FO) abolished most of the metabolic responses to ED injection. Both HCO and FO could influence the response via a reduction in prostaglandins and leukotrienes by reducing the formation of arachidonic acid (AA) precursor of eicosanoids. Fatty acids composition analysis from the PC fraction of the spleen showed a decreased amount of AA in the order of FO > HCO > CO. Pretreatment with the cycloxygenase inhibitor, indomethacin blocked body weight loss, prevented protein loss from peripheral tissues, and affected the elevation of serum corticosterone; whereas the lipoxygenase inhibitor AA861 inhibited ED-induced hypozincemia, and muscle cathepsin B activity. Total liver protein was unaffected by inhibitors, and HCO or FO feeding. T ese data suggested that many of the endotoxin-induced metabolic changes are controlled by metabolites of AA, and that the acute-phase proteins synthesis by the liver is independent of eicosanoids production. Dietary fats manipulation moderated the metabolic responses to E. coli endotoxin through both pathways. (D74421/87)</p
Типы компьютерных сетей – LAN, MAN и WAN
No full textВ данной статье рассмотрены основные виды сетей, которые используются каждый день человеком. Цель данной стати является объяснение рядовому пользователю в чем разница между различными сетями LAN, MAN и WAN
Relating agent loyalty and agent image in Hong Kong travel industry.
No full textby Wan Man-fong Sylvia.Thesis (M.B.A.)--Chinese University of Hong Kong, 1988.Bibliography: leaves 58-59
A review of the problems encountered in private large scale redevelopment schemes.
No full textby Wan Man-Leung.Thesis (M.B.A.)--Chinese University of Hong Kong, 1985.Bibliography: leaves 64
A study on the employment of consultancy services in Hong Kong business sector.
No full textby Wan Siu-Man, Monisa.Thesis (M.B.A.)--Chinese University of Hong Kong, 1989.Bibliography: leaves 89-90
Chinese literary works translated into Baba Malay: a bibliographical study
No full textAnalyses 68 unique titles of Baba translated works published between 1889 and 1950. The titles are held in the libraries of the University of Malaya (UM), Science University Malaysia (USM), National University of Malaysia (UKM), the Dewan Bahasa dan Pustaka (DBP), National University of Singapore (NUS), National Library of Singapore (NLS) and the British Library (BL). The results reveal three periods of active publication of Baba translated works. A total of 18 works were translated before World War I, followed by 10 just after the war, 39 titles were published before the break of the World War II and 1 was identified in 1950. There were 103 persons involved in the 68 translated works, some of whom are responsible for more than one title. The most prominent translators were Chan Kim Boon, Wan Boon Seng, Seow Chin San and Lee Seng Poh. Some of the translators were also be editors, illustrators or editors. There were 31 publishers and 21 printing presses involved, all were located in Singapore. The most active publishers were Wan Boon Seng, Kim Seck Chy Press and Nanyang Romanised Malay Book Co. The translated works mainly cover historical classical Chinese stories, chivalrous stories, romances, folklore and legends. The titles were priced between 10 cents to 2 dollars in Straits currency. The University of Malaya Library held the largest number of unique title (62) out of which 15 were unique titles
Urban web: pedestrianization in Hong Kong.
No full textWan Yee Man Emma."Architecture Department, Chinese University of Hong Kong, Master of Architecture Programme 1996-97, Design Report."Includes bibliogrpahical references (leaves i-ii (last gp.)).ACKNOWLEDGMENTINTRODUCTIONDESIGN OBJECTIVESPROJECT SELECTIONPROJECT NATURECLIENTUSERSSITE/ CONTEXTWALKING WITHIN A CITY???PROCESSURBAN SCALEMISSIONPROBLEM AND OPPORTUNITIESSITE STUDYURBAN CONCEPTSURBAN PROPOSALSDEVELOPMENTS AT THE INTERVENTIONSBUILDING SCALEMISSIONSCHEDULE OF ACCOMMODATIONSPATIAL RELATIONSHIPCONCEPT11 X 11 M MODULAR GRIDMASSING ISSUECIRCULATIONDETAIL DESIGNIMAGE DEVELOPMENTMATERIALS/ FINISHES/TEXTUREFINAL PROJECTURBAN SCALEBUILDING SCALEAFTER THOUGHTSAPPENDI
Geology of Mo Tat Wan
No full textA study has been conducted on the southwest and northeast coasts of Mo Tat Wan on Lamma Island. The purposes of this was to examine the different lithologies of Mo Tat
Wan to determine their relative ages, investigate geological structures by examining kinetic indicators to determine the directions of fault movements and to construct the geological evolutions over the area. Field mapping and microscopic analysis was from February, 2016 to acquire the data to produce a set of 1:1,000-scale inferred geological maps detailing the relative age relationship between lithologies and locations of geological structures. Key findings are that the estimated width of quartz monzonite and the configuration basaltic andesite dyke located at the southwest coast of Mo Tat Wan are somewhat different from what have been annotated in the 1:20,000-scale HKGS Geological Map Sheet 15 (GEO, 2010). For the aspects related to geological structures, the nature and characteristics of kinematic indicators reveal that the past deformations were brittle to semi-brittle with both sinistral and dextral movements. A post-shearing emplacement of mafic dyke was noted with the infilling of mafic materials into the tension gashes observed at the southwestern coast of Mo Tat Wan. The “autobrecciation” (Strange and Shaw, 1986) of quartzphyric rhyolite dyke located at the northeastern coast of Mo Tat Wan (approximately 80 m southeast to the Mo Tat Wan Public Ferry Pier) was observed to be about 3 m wide and the brecciation zone with deformed quartz crystal was likely to be associated with a NW-SE striking fault.published_or_final_versionApplied GeosciencesMasterMaster of Scienc
Transkrip wawancara bersama Samad bin Man tokoh adiguru wau / Wan Edzzuddin Najmi Abdullah and Amratul Azizah Hayazelee
No full textTranskrip temubual ini dilakukan oleh pelajar UiTM Cawangan Kelantan iaitu Wan Edzzuddin Najmi Bin Abdullah dan Amratul Azizah Binti Hayazelee bersama Tokoh Adiguru Wau, iaitu Tuan Samad Bin Man. Tujuan transkrip ini adalah untuk mengetahui tentang sejarah diri beliau, juga anugerah dan sumbangan beliau selama berkhidmat sebagai seorang pengukir kayu. Temubual ini telah dijalankan di Kangar, Per/is. Tarikh temubual tersebut adalah pada 31 Januari 2022 bermula padajam 8.45 pagi hingga 1 Februari 2022 pada jam 9.45 pagi. Tuan Samad Bin Man berpengalaman selama 30 tahun sebagai tukang pembuatan wau bertempat di Kangar, Perlis. Pencapaian yang paling membanggakan beliau apabila menyandang anugerah Tokoh Adiguru Wau atas sumbangannya dalam penyertaannya dan penglibatannya dalam pertandingan menerbangkan wau di beberapa buah Negara. Sejarah kehidupan dan pencapaian beliau dapat dijadikan sumber inspirasi kepada semua orang, terutamanya kepada generasi muda dalam pembuatan wau
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