973 research outputs found
Green in water sonochemical synthesis of tetrazolopyrimidine derivatives by a novel core-shell magnetic nanostructure catalyst
Get PDFA green approach for the one-pot four-component sonochemical synthesis of 5-methyl-7-aryl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxylic esters from the reaction of 2-cyano-guanidine, sodium azide, various aromatic aldehydes and methyl or ethyl acetoacetate in the presence of a catalytic amount of Fe₂O₃@SiO₂-(CH₂)₃NHC(O)(CH₂)₂PPh₂ as a new hybrid organic–inorganic core–shell nanomagnetic catalyst is described. This is the first design, preparation, characterization and application of the present nanomaterial and also the first ultrasound irradiated synthesis of the biologically and pharmaceutically important heterocyclic compounds in water as a green solvent. This novel sonocatalysis/nanocatalysis protocol offers several advantages such as high yields, short reaction times, environmentally-friendly reaction media, easily isolation of the products, simple preparation, full characterization and recoverability of the nanocatalyst by an external magnet and reusing several times without significant loss of activity.The authors gratefully acknowledge the partial support from the Research Council of the Iran University of Science and Technology (IUST). The equipment in the Center of Synthesis and Analysis BioNanoTechno of University of Bialystok was funded by the EU as part of the Operational Program Development of Eastern Poland 2007–2013, project: POPW.01.03.00–20–034/09 and POPW.01.03.00-004/11. The support from the Polish National Science Centre (NCN grants number 2012/05/B/ST5/00362) is gratefully acknowledged.Ali Maleki: [email protected] Maleki - Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, IranJamal Rahimi - Catalysts and Organic Synthesis Research Laboratory, Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, IranOleg M. Demchuk - Department of Organic Chemistry, Maria Curie-Sklodowska University, Gliniana 33, Lublin 20-614, PolandAgnieszka Z. Wilczewska - Institute of Chemistry, University of Białystok, Ciołkowskiego 1K, 15-245 Białystok, PolandRadomir Jasiński - Institute of Organic Chemistry and Technology, Cracow University of Technology, Warszawska 24, Cracow, PolandJ. Zhu, H. Bienaymé, Multicomponent Reactions, John Wiley & Sons, 2006.A. Maleki, A. Sarvary, Synthesis of tetrazoles via isocyanide-based reactions, RSC Adv. 5 (2015) 60938–60955.A. Sarvary, A. Maleki, A review of syntheses of 1,5-disubstituted tetrazole derivatives, Mol. Divers. 19 (2015) 189–212.A. Maleki, P. Ravaghi, M. Aghaei, H. Movahed, A novel magnetically recyclable silver-loaded cellulose-based bionanocomposite catalyst for green synthesis of tetrazolo[1,5-a]pyrimidines, Res. Chem. Intermed. 43 (2017) 5485–5494.X. Wang, Y. Wei, Y. Da, Z. Zhang, Z. Quan, One-step synthesis of tetrazolo[1,5-a] pyrimidines by cyclization reaction of dihydropyrimidine-2-thiones with sodium azide, Heterocycles 83 (2011) 2811–2822.T. Li, C. Yao, C. Yu, X. Wang, S. Tu, Ionic liquid–mediated one-pot synthesis of 5-(trifluoromethyl)-4,7-dihydrotetrazolo[1,5-a]pyrimidine derivatives, Syn.Commun. 42 (2012) 2728–2738.M.V. Goryaeva, Y.V. Burgart, M.A. Ezhikova, M.I. Kodess, V.I. Saloutin, Reaction of 2-(ethoxymethylidene)-3-oxo carboxylic acid esters with tetrazol-5-amine, Russ. J. Org. 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Varma, Nano-magnetite (Fe₃O₄) as a support for recyclable catalysts in the development of sustainable methodologies, Chem. Soc. Rev. 42 (2013) 3371–3393.A. Maleki, H. Movahed, R. Paydar, Design and development of a novel cellulose/γFe2O3/Ag nanocomposite: a potential green catalyst and antibacterial agent, RSC Adv. 6 (2016) 13657–13665.A. Maleki, One-pot three-component synthesis of pyrido[2',1':2,3]imidazo[4,5-c] isoquinolines using Fe3O4@SiO2–OSO3H as an efficient heterogeneous nanocatalyst, RSC Adv. 4 (2014) 64169–64173.A. Maleki, H. Movahed, P. Ravaghi, Magnetic cellulose/Ag as a novel eco-friendly nanobiocomposite to catalyze synthesis of chromene-linked nicotinonitriles, Carbohydr. Polym. 156 (2017) 259–267.A. Maleki, H. Movahed, P. Ravaghi, T. Kari, Facile in situ synthesis and characterization of a novel PANI/Fe3O4/Ag nanocomposite and investigation of catalytic applications, RSC Adv. 6 (2016) 98777–98787.A. Maleki, M. Aghaei, R. 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Typescript Bill H.R. 20819 for the Construction of Roads and other Permanent Improvements
No full textTypescript draft of Bill H.R. 20819 to provide for the construction of roads and other permanent improvements at or near the Grand Canyon. The sum of $110,000 dollars is to be appropriated for the project under the direction of the Secretary of Agriculture
Innovative Ways of Dealing with Existing Problems: How to reliably Assess the Cause of Damage of Masonry Structures in an Area with Man-induced Earthquakes?
No full textGroningen, a province in the northern part of the Netherlands, suffers from earthquakes because of gas drilling. The residential building stock in Groningen was not designed for these loads. Over the years a lot of smaller and larger damage has developed, possibly - but not necessarily - caused by the effects of gas drilling. Delft University of Technology was asked by the Dutch government to come up with a method to reliably assess the cause of damage of masonry structures in Groningen. This paper discusses the developed approach for reliably assessing the causes of failure of masonry structures in earthquake-prone areas and the way innovative monitoring techniques were applied.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Applied Mechanic
Efficient material use through smart flexible formwork method
No full textConcrete is an excellent material for application in free-form architecture as a result of its initial fluid state. Double-curved building shapes have been realized in various fibre-reinforced mixtures, using advanced CNC-milled formwork systems. However, a substantial reduction of material use is still possible on two ends: by using a flexible formwork very thin and structurally efficient elements can be manufactured, reinforced with fibres or textiles. Moreover, the reusability of the flexible formwork considerably limits the waste material that was always remaining after the use of milled formwork systems. This paper discusses experiments with both formwork and mixtures in a PhD-study of the first author, demonstrating the ecological potential of this innovative production method.Structural EngineeringCivil Engineering and Geoscience
Cosmetic Testing on Animals
No full textPushing the Humane Cosmetics Act (H.R.4148) both to Remove Harmful Ingredients from Cosmetics and Promote the Health and Welfare of AnimalsFall 2014Accompanied by video fil
Bundeling van zonlicht door gekromde gevels: Een concreet probleemgeval onderzocht met parametrische tools, simulatie en controlemetingen
No full textWat te doen als je prachtige gekromde glazen gevel onverwacht als vergrootglas blijkt te werken? Het fenomeen, dat al enigszins bekend was van de beruchte “Walkie Talkie” in Londen, is al eens eerder beschreven in Bouwfysica in 2018 [1]. Helaas kon dat artikel niet voorkomen dat ook in Nederland dit probleem vorig najaar plotseling optrad bij een nieuw gebouw dat op het punt stond opgeleverd te worden. Smeltende auto-onderdelen op het ondergelegen parkeerterrein, mogelijk gevaar voor bezoekers en een ongeruste opdrachtgever waren het resultaat. Parametrische tools en software voor simulatie van bezonning hielpen het ontwerpteam en de opdrachtgever om samen te zoeken naar de meest geschikte oplossing.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Applied MechanicsEnvironmental & Climate Desig
Time-Dependent Behaviour of Polymers and Unidirectional Polymeric Composites
No full textMechanical Maritime and Materials Engineerin
Nilai Budaya Pada Novel Gugur Bunga Kedaton Karya Wahyu H.R: Kajian Antropologi Sastra Dan Implementasinya Dalam Pembelajaran Sastra Di Sma
Get PDFThis study has four objectives. Describe the social background of historical authorship of Wahyu H.R. Describe the structure builders novel GBK work of Wahyu H.R. Describe the cultural values embodied in the novel GBK work of Wahyu H.R. Explained implementation of novel research results GBK of Wahyu H.R work in teaching literature in high school. This study uses descriptive qualitative method. Object of research is cultural values contained in the novel GBK of Wahyu H.R with a review of the anthropological literature. The data in this study a paragaf, sentences, and words related to novel structures and cultural values. The primary data source in this study is novel GBK. While secondary data sources in the research is a biography of the author and literary authors. Data collection techniques used are literature, see, and record. Validation data using triangulation theory. Data were analyzed using heuristic and hermeneutic reading method. In the novel there are five cultural values were analyzed using the theory presented by Djamaris. This value includes the value of culture in the human relationship with God which consists of the value ketawakalan, piety, faith in destiny, grateful, and pleasure, the value of culture in human relationships with the society of the value of consensus, mutual cooperation, harmony or balance, and solidarity ,cultural values in human relationships with others that consist of the value of love, loyalty, obedience to parents, and wisdom, the value of culture in the human relationship with yourself that consists of the value of willpower, study, live custom and religion, courage and vigilance, and cultural values in human relationships with nature consisting of human values that unite with nature and human nature conquered or utilize. Implementation of cultural value in GBK novel as literature in high school teaching materials appropriate and relevant learning materials to be used as literature. GBK novel contains elements of intrinsic and extrinsic elements. Intrinsic element is implemented to the students to find a theme, a fact the story and the story means. Extrinsic elements of the novel are implemented to discover cultural values contained in the novel
No-Fault Peer Review Charges: The Price of Selectivity Need Not Be Access Denied or Delayed
No full textPlans by universities and research funders to pay the costs of Open Access Publishing ("Gold OA") are premature. Funds are short; 80% of journals (including virtually all the top journals) are still subscription-based, tying up the potential funds to pay for Gold OA; the asking price for Gold OA is still high; and there is concern that paying to publish may inflate acceptance rates and lower quality standards. What is needed now is for universities and funders to mandate OA self-archiving (of authors' final peer-reviewed drafts, immediately upon acceptance for publication) ("Green OA"). That will provide immediate OA; and if and when universal Green OA should go on to make subscriptions unsustainable (because users are satisfied with just the Green OA versions) that will in turn induce journals to cut costs (print edition, online edition, access-provision, archiving), downsize to just providing the service of peer review, and convert to the Gold OA cost-recovery model; meanwhile, the subscription cancellations will have released the funds to pay these residual service costs. The natural way to charge for the service of peer review then will be on a "no-fault basis," with the author's institution or funder paying for each round of refereeing, regardless of outcome (acceptance, revision/re-refereeing, or rejection). This will minimize cost while protecting against inflated acceptance rates and decline in quality standards
How Inverse Blended Learning can Turn Up Learning with MOOCs?
No full textMassive Open Online Courses (MOOCs) have been a hype in technologyenhanced learning systems the last couple of years. The promises behindMOOCs stand on delivering free and open education to the public, as well astraining a large criterion of students. However, MOOCs clashes severely withstudents dropout which by then forced educationalists to deeply think ofMOOCs effectivity from all angles. As a result, the authors of this paper proposea pedagogical idea that strongly depends on injecting the online learning(MOOC) with face-to-face sessions to refresh the students minds as well as integrating them in the real learning process. The authors after that analyze the results of their experiment using Learning Analytics. The outcomes have shown anew record of certification ratio (35.4%), an improvement of student interactionin the MOOC platform, and a manifest in social interaction in the MOOC discussion forum.Web Information System
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