1,720,957 research outputs found
Design and Development of Radio Frequency Coils for Sodium Magnetic Resonance Imaging at 7 T
The main goal of this Thesis is the design and development of Radio-Frequency (RF) coils for sodium Magnetic Resonance Imaging (MRI) at Ultra High Field (UHF). The advantage of using UHF MR scanners is due to the possibility to achieve improved Signal-to-Noise-Ratio (SNR) and spatial resolution. These characteristics are fundamental in case of imaging with nuclei different from proton, which provide an intrinsically lower signal because of their lower in-vivo concentration and lower gyromagnetic ratio. Moreover, the overlap between sodium and proton images allows the accurate localization of regions with an anomalous sodium concentration, thanks to the anatomically more detailed proton images. For this reason, in case of imaging with non-proton nuclei, Dual-Tuned (DT) coils are preferable, since they allow the signal acquisition in a fixed spatial orientation of the subject, thus removing the need of patient’s repositioning between two consecutive acquisitions with two different RF coil resonating at the two Larmor frequencies of proton and sodium, respectively. Therefore, with a DT coil, automatically co-registered images can be obtained. The cost to pay is an increase in the design and development complexity with respect to a standard RF coil.
In this Thesis, RF coils prototypes for sodium imaging (Larmor frequency ≃ 79 MHz) have been designed and developed for two different applications: human knee and human head imaging. Concerning the knee imaging, both surface coils, suitable for the signal reception, and volume coils, suitable for the sample excitation, have been designed and developed. All surface coils for knee imaging are dual-tuned. The first DT-RF coil prototype has been developed to study and characterize the issues related to the coupling between the two resonant structures, which usually compose a DT coil. New decoupling strategies have been proposed and developed as an alternative to the standard decoupling by using trap circuits, including models based on PIN diodes and Micro-Electro-Mechanical System (MEMS) switches. The volume RF coil for the knee imaging, built to be sensitive to the sodium signal only, has been designed according to the birdcage model. It has been developed to face with potential issues related to sodium volume coil interfacing with the MR system and signal acquisition before starting the construction of DT volume coils. Concerning the head imaging, an imbricated DT-RF coil, consisting of two concentrically placed birdcages, and the related electronic interface needed to connect the coil to the MR system, have been developed. Finally, an unconventional DT volume coil model (four-ring model), consisting of two birdcage-like resonant structures arranged on the same cylindrical surface and tuned at the two frequencies of interest, has been taken into account. The four-ring model has been optimized though electromagnetic simulations, with the main purpose of increasing the magnetic field homogeneity at the proton Larmor frequency at 7 T (≃ 300 MHz), and finally compared with the imbricated model
Numerical and Workbench Design of 2.35 T Double-Tuned (1H/23Na) Nested RF Birdcage Coils Suitable for Animal Size MRI
The birdcage Radio Frequency (RF) coil is one of the most used configurations in Magnetic Resonance Imaging (MRI) scanners for the detection of the proton (1H) signal over a large homogeneous volume. More recently, birdcage RF coils have been successfully used also in the field of X-nuclei MRI, where the signal of a second nucleus (e.g. 13C, 23Na, 31P, and many others) needs to be detected with high sensitivity and spatial homogeneity. To this purpose several technical solutions have been adopted to design Double Tuned (DT) volume RF coils, including the recent configuration of the nested birdcage RF coils. One of the main problems in the design of DT RF coils is the decoupling between the 1H and X channels, and a number of solutions have been adopted over the years. In this work, based on numerical and workbench methods, we report the decoupling optimization of DT (1H/23Na) nested RF birdcage coils suitable for 2.35 T MRI scanners encompassing an inner Low-Pass (LP) birdcage used for X-nuclei, an outer High-Pass (HP) birdcage for 1H and an external cylindrical RF shield. We show that a suitable geometrical selection of the two coaxial RF birdcage coils (relative angular orientation, diameters and lengths) and RF shield (diameter, length) allows a significant decoupling optimization. We also provide valuable information about the RF B1+ field homogeneity and efficiency. Our approach was validated both with numerical simulations and workbench testing using DT nested RF coil prototypes
Experimental Setup to Compare Measurements and Numerical Simulations in Magnetic Resonance Imaging RF Dosimetry
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Analisi di un Sistema "Wireless Power Transfer" Transcutaneo per Cuore Artificiale
Si propone un sistema “Wireless Power Transfer” transcutaneo per l’alimentazione di cuori artificiali. Il sistema può essere visto come una rete due porte ed è costituito da due elementi: un loop in trasmissione esterno e un loop in ricezione impiantato sotto cute. Ognuno dei due loop è dotato di un capacitore posto in serie ad essi. I valori di capacità sono stati scelti in modo da massimizzare il parametro |S21| alla frequenza di 13.56MHz. Tale parametro tiene conto di quanta parte della potenza trasmessa alla porta 1 viene effettivamente ricevuta alla porta 2, sotto l’ipotesi di carico adattato. I tessuti umani sono stati modellati come mezzi dispersivi tramite il modello di debye del secondo ordine. Per il progetto e l’analisi del sistema è stato usato il software CST Microwave Studio, che implementa il metodo di analisi agli elementi finiti (FEM). Successivamente è stata analizzata la distribuzione del SAR locale all’ interno dei tessuti e confrontata con i limiti imposti dalla normativa ICNIRP
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