1,720,965 research outputs found
Linezolid resistance in a Staphylococcus haemolyticus strain isolated in an intensive care unit
No full textposter P89
Performance of different commercial methods for determining minimum inhibitory concentrations of glycopeptides and linezolid against blood isolates of Staphylococcus aureus
No full textThe aim of this study was to determine the accuracy of commercial
systems (VITEK (R) 2, Etest and Sensititre (R)) in determining the
minimum inhibitory concentrations of vancomycin, teicoplanin and
linezolid of Staphylococcus aureus strains and to evaluate the
reproducibility of each system in a clinical microbiology laboratory. In
total, 115 strains of S. aureus isolated from blood cultures were tested
with all three commercial methods as well as the broth microdilution
method, which is designated as the standard for glycopeptides and
linezolid. Fourteen different S. aureus strains were included in a
reproducibility test for all methods and antibiotics. For these strains,
antimicrobial susceptibility testing was repeated 10 times on different
days with all four methods, each time using the same inoculum. All three
commercial methods exhibited similar performance in categorisation of
nearly all of the meticillin-susceptible S. aureus (MSSA) isolates.
Discrepancies were registered for meticillin-resistant S. aureus (MRSA);
2.5\% of the strains in the intermediate or resistant category with the
VITEK 2 system were not recognised as resistant by Etest and Sensititre.
Moreover, none of the three commercial methods provided accurate results
compared with homemade broth microdilution. Reproducibility of
vancomycin and teicoplanin was 100\% with VITEK 2 and Sensititre and
98.75\% with Etest. Microdilution showed a reproducibility of 95.6\%
with vancomycin and 83.1\% with teicoplanin. In contrast to previous
reports, the best agreement with microdilution was exhibited by VITEK 2
both for MSSA and MRSA. For the antibiotics tested, the best
reproducibility was obtained with the VITEK 2 and Sensititre systems.
(C) 2013 International Society for Chemotherapy of Infection and Cancer.
Published by Elsevier Ltd. All rights reserved
Outbreak of linezolid-resistant Staphylococcus haemolyticus in an Italian intensive care unit
No full textWe report an outbreak of linezolid-resistant Staphylococcus haemolyticus strains (MIC 32 mg/L) in patients admitted to the Verona University Hospital Intensive Care Unit. The strains proved to be clonally related at pulsed field gel electrophoresis. All the strains showed the G2576T mutation responsible for linezolid-resistance and retained their resistance even after several passages on antibiotic-free medium. After a decade of linezolid use, multifocal emergence of linezolid resistance in coagulase-negative staphylococci has become an important matter of concern and mandates stricter control over the use of this antibiotic in order to preserve its clinical utility
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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