376 research outputs found
Supplementary_File – Supplemental material for Biomass co-pyrolysis: Effects of blending three different biomasses on oil yield and quality
No full textSupplemental material, Supplementary_File for Biomass co-pyrolysis: Effects of blending three different biomasses on oil yield and quality by Derya Yeşim Hopa, Oğuzhan Alagöz, Nazan Yılmaz, Meltem Dilek, Gamze Arabacı and Tunçer Mutlu in Waste Management & Research</p
Riemann'ın sınır değer problemi
No full textCataloged from PDF version of article.Includes bibliographical references (leave 77).We study the Riemann boundary value problem with finite and infinite index. The basis of the solution of the problem with the finite index is the Plemelj-Sokhotski formula. The solution of the problem with infinite index depends not only on the Plemelj-Sokhotski formula but also on some results of the entire functions theory.by Ayşe Mutlu Dery
THE EFFECT OF GLOBAL LONGITUDINAL STRAIN ON IMPAIRED SIX-MINUTE WALK TEST PERFORMANCE IN PATIENTS WITH SARCOIDOSIS
No full textBackground: Sarcoidosis is a multisystem and granulomatous disease associated with impaired functional capacity as a result of pulmonary and cardiac involvement. Factors adversely effecting functional capacity in patients with sarcoidosis have not been systematically assessed including myocardial strain imaging on echocardiography which enable to diagnose subclinical cardiac dysfunction. We aimed to evaluate the effect of left and right ventricular global longitudinal strain (GLS) on submaximal exercise capacity in patients with sarcoidosis who do not have clinically manifest cardiac involvement. Methods: Extracardiac biopsy proven 56 patients with sarcoidosis and 26 controls were included consecutively. Submaximal exercise capacity of the subjects was assessed with six-minute walk test (6 MWT). Pulmonary function tests and standard transthoracic and two-dimensional speckle tracking echocardiography were performed to the all subjects. Linear regression analysis was performed to find independent predictors of 6 MWT. Results: Fifty-six patients (18% male) with a mean age of 52.5 +/- 10.7 years were included. Patients with sarcoidosis had low 6 MWT performance and higher New York Heart Association classes and NT-proBNP levels. There were no significant differences between controls and patients with sarcoidosis in parameters of pulmonary function test. Biventricular GLS levels and biatrial reservoir and conduit function values were lower and systolic pulmonary artery pressure (SPAP) was significantly higher in patients with sarcoidosis as compared with controls. Older age and higher SPAP were found as independent predictors of poor 6 MWT performance. Conclusion: Although biventricular GLS levels were lower in the patients with sarcoidosis, only age and SPAP elevations were independent predictors of the submaximal exercise capacity
Real-life data of direct anticoagulant use, bleeding risk and venous thromboembolism recurrence in chronic thromboembolic pulmonary hypertension patients: an observational retrospective study
No full textIntroduction Lifelong anticoagulation is the cornerstone of the chronic thromboembolic pulmonary hypertension (CTEPH) treatment regardless of the additional pulmonary endarterectomy, balloon pulmonary angioplasty, or medical treatment alone. Aim of this study was to evaluate the rate of oral anticoagulant preferences and document direct oral anticoagulants' (DOACs') safety, efficacy in the CTEPH population. Methods Patients' demographic data obtained from database between September 2011 and April 2018. In-hospital events, death, venous thromboembolism (VTE) recurrence, bleeding events and anticoagulant therapy transition were recorded. Results We reviewed 501 CTEPH patients who observed 9.0 +/- 8.5 years. All-cause death, all bleeding, recurrent VTE was observed in 15.6%, 31% and 12%. Forty-one patients (8.2%) were diagnosed as inoperable. Of all, 15.2% of operable patients remained as residual. All-cause mortality rates were 13.8% (57 pts.) in the warfarin group as compared with 9.7% (13 pts.) in rivaroxaban group (HR: 1.61, 95% CI, 0.89-2.99; p: 0.11). Higher bleeding events occurred with warfarin group (27.1%) as compared with rivaroxaban (24.6%; HR: 1.28, 95% CI, 0.86-1.88; p: 0.22). Major bleeding was significantly higher with warfarin group (HR: 1.94, 95% CI, 1.05-3.62; p: 0.03). Subgroup analysis of all-cause death revealed that this significance dominated by the rate of death according to bleeding events; warfarin versus those seen with rivaroxaban (4.85% vs. 2.2%; HR: 4.75, 95% CI: 1.12-20.16; p = 0.03). The rate of recurrent VTE was found 8.9% in the rivaroxaban group, 10.9% in warfarin group (HR: 1.21, 95% CI, 0.64-2.23; p: 0.55). Conclusion DOACs could be a safe and effective alternative for lifelong anticoagulant therapy in CTEPH patients. Rivaroxaban produced similar rates of thromboembolism and non-relevant bleeding compared to those associated with warfarin. The main difference was found with major bleeding that it was mainly associated with the death rate according to major bleeding. Using DOACs might be a more reasonable way to prevent bleeding events without increasing thromboembolic risk
Respiratory and peripheral muscle involvement in patients with pulmonary arterial hypertension due to congenital heart diseases
No full textSkeletal and respiratory muscle dysfunction has been previously described in patients with other etiologic subgroups of pulmonary arterial hypertension (PAH) but has never been investigated in patients with PAH due to congenital heart diseases (CHD). This study aims to show the involvement of skeletal and respiratory muscles in these patients. This cross-sectional study included patients with PAH due to CHD and healthy controls. Patients’ demographic properties, six-minute walk tests; shoulder abduction, handgrip, knee extension, and ankle dorsiflexion muscle strength, maximum inspiratory (MIP) and expiratory pressures (MEP) were measured. Deltoid, flexor digitorum superficialis, and profundus, tibialis anterior and rectus femoris muscles were visualized with ultrasonography and their cross-sectional areas (CSA) were also measured in both groups. 12 patients and 12 controls were included. Mean MIP was 104.22±32.57 cm H2O for healthy participants while 61.33±29.74 cm H2O for patients (p<0.001). For mean MEP, it was 100.08±26.05 cm H2O in healthy participants and 69.75±39.79 cmH2O in controls (p=0.004). When the strength of skeletal muscles was compared, there were significant differences between the groups in all measurements except for bilateral grip strength. In the correlation analysis, MIP and MEP values showed no significant correlations with clinical parameters. They showed significant moderate correlations with skeletal muscle strength. When CSAs of the muscles were compared, there were significant differences in all measurements except for left FDS and FDP and bilateral rectus femoris. This study showed that in patients with pulmonary arterial hypertension due to CHD, respiratory muscle strength is significantly worse than healthy participants. Patients had also significantly worse skeletal muscle strength except for grip strength
The Relationship Between Caregiver Burden and Psychosocial Adjustment of Patient’s Relatives in Intensive Care Unit
No full textAmaç: Bu araştırma dahiliye yoğun bakım ünitesinde yatan hastaların yakınlarının bakım verme yükünü, psikososyal uyumlarını ve bunlar arasındaki ilişkiyi ve etkileyen faktörleri değerlendirmek amacıyla yapılmıştır. Gereç ve Yöntem: Kesitsel ve ilişkisel nitelikte, tanımlayıcı türde tasarlanan bu araştırma tek grupta anket çalışması olarak yürütülmüştür. Çalışmaya, dahiliye yoğun bakımında tedavi olan 100 hasta yakınından/ bakım vereni dahil edilmiştir. Verilerin toplanmasında, Tanıtıcı Bilgi Formu, Bakım Verme Yükü Ölçeği (BVYÖ) ve Hastalığa Psikososyal Uyum-Öz bildirim Ölçeği (PAIS-SR) kullanılmıştır. Veriler, tanımlayıcı istatistikler, t testi ve varyans analizi ile değerlendirilmiştir. Bulgular: Bakım verenlerin %72’si kadın ve yaş ortalaması 42.74 ± 9.83’dür. %72’si evli olan bakım verenlerin %51’i eşi ve çocuklarıyla birlikte yaşamaktadır ve %50’si bakmakla yükümlü olduğu başka birey(ler)in de olduğunu ifade etmiştir. Bakım verenlerin %27’si yaşadığı stresle baş edemediğini, %12’si öfkesini kontrol edemediğini belirtmiştir. Hasta yakınlarının hastalığa psikososyal uyum puan ortalaması 55.07±18.10 ve bakım verme yükü puan ortalaması 32.85±12.34 olarak bulunmuş ve her iki ölçek puan ortalaması arasında istatistiksel olarak anlamlı düzeyde doğru orantılı bir ilişki olduğu saptanmıştır (p<.01). Hasta yakınlarının bazı sosyo-demografik değişkenleri bakım verme yüklerini ve hastalığa psikososyal uyumlarını etkilemektedir. Sonuç: Dahiliye yoğun bakımda yatan hasta yakınlarının bakım verme yükü ile psikososyal uyumları orta düzeyde olup, bakım vermeye yönelik algıladıkları sıkıntı arttıkça, hastalığa psikososyal uyumları kötüleşmektedir. Hasta yakınlarının bakım verme yükü algıları ile psikososyal uyumları bazı sosyodemografik özelliklerinden etkilenmektedir.
Objective: The aim of this study is to examine the relationship between caregiver burden and psychosocial adjustment and affecting factors of caregivers/relatives of patients who were in the internal medicine intensive care unit. Material and Methods: The research was designed in a descriptive and cross-sectional and was conducted as a survey study in a single group. This study was conducted with a hundred (100) caregivers of patients who were treated in an intensive care unit. Data were collected using three forms: Introductory Information Form, the Caregiver Burden Scale (BVYÖ) and the Psychosocial Adjustment to Illness Scale (PAIS-SR). The data were evaluated by descriptive statistics, t-test and variance analysis. Findings: 72% of the caregivers are women and the average age is 42.74±9.83. 72% of caregivers are married and 51% live with their spouse and children and 50% stated that there is another individual(s) they are obliged to look after. 27% of caregivers stated that they could not cope with the stress and 12% could not control their anger. Caregivers’ psychosocial adjustment mean score was 55.07±18.10 and caregiver burden mean score was 32.85±12.34, and statistically significant correlation was found between both scales. Some socio-demographic variables of patient relatives affect their caregiver burden and psychosocial adjustment to the disease. Conclusion: The caregiving burden and psychosocial adjustment of the patient’s relatives of the hospitalized patients in the intensive care unit is at a moderate level. As the perceived distress/burden of caregivers increases, their psychosocial adjustment to the disease worsens. Patient relatives’ perceptions of caregiver burden and psychosocial compatibility are affected by some socio-demographic characteristics
Caregiver Burden in Patients with Pulmonary Hypertension
No full textBoth quality of life (QoL) and caregiver burden are essential constructs in patients with pulmonary hypertension (PH) however; their relationship has never been investigated before. The aim of this study was to evaluate if there was any relationship between patients' QoL and caregiver burden. Patients with PH and their caregivers were included. Patients' age, sex, World Health Organization (WHO) functional class, systolic pulmonary arterial pressure (sPAP), and six-minute walk distances (6MWD) were recorded. Patients' QoL was assessed using emPHasis-10 and caregiver burden with the Zarit Caregiver Burden Scale. 72 patient-caregiver dyads were included. Caregiver burden was significantly correlated with the QoL(r = 0.39 p < .003), but was not correlated with other clinical parameters. Patients' QoL showed significant negative correlation with the 6MWD(r = -0.46 p < .005). There is a moderate correlation between QoL and caregiver burden. Clinical parameters influence QoL, but they do not affect caregiver burden
Balloon Pulmonary Angioplasty in Patients With Inoperable or Recurrent/Residual Chronic Thromboembolic Pulmonary Hypertension
No full textBackground Methods Results Conclusion
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