134,437 research outputs found

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    VKS3-008 - Kastom Stori, Mota and Gaua

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    (A) Andrew Sur Tasmate, Mota (B) Mota Head Tsif Jonathan Wogales Kwetebut Gaua. . Language as given

    HLA and hemochromatosis disease association in São Miguel Island

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    Mestrado em Biologia Molecular e CelularA hemocromatose hereditária uma doença autossómica recessiva do metabolismo do ferro, geralmente associada à mutação C282Y no gene HFE. Presume-se que a origem desta mutação tenha ocorrido por acaso no haplótipo HLA-A*03-B*07 de um indivíduo do noroeste da Europa. O presente trabalho visou caracterizar a associação entre os alelos e haplótipos dos loci HLA-A e -B com a mutação C282Y na população da ilha de São Miguel (Açores). Este estudo englobou 130 indivíduos, negativos para as mutações HFE H63D e S65C, que foram classificados em dois grupos: grupo C282Y (48 homozigóticos ou portadores da C282Y) e grupo controlo (82 dadores de sangue sem as três mutações no gene HFE). Para todos os indivíduos, foi efectuado a genotipagem HLA-A e -B por PCR-SSP e a detecção das mutações HFE por PCR-RFLP. A análise estatística revelou que quatro alelos – A*03 (p=0.003, OR=3.33), A*26 (p=0.003, OR=8.38), A*29 (p<0.001, OR=19.18) e B*45 (p=0.003, OR=8.37) – encontram-se significativamente aumentados no grupo C282Y. Os resultados demonstram, igualmente, uma associação significativa com a mutação C282Y para o haplótipo ancestral HLA-A*03-B*07 (p=0.006, OR=8.96) e dois haplótipos não ancestrais: A*02-B*58 (p<0.001, OR=19.78) e A*29-B*45 (p<0.001, OR=27.57). Além disso, outro haplótipo A*24-B*15 foi detectado por inferência directa num doente homozigótico para o HLA-A-B e para a mutação C282Y. Provavelmente, o mecanismo genético de recombinação gerou esta diversidade de haplótipos; no entanto, não se pode excluir a hipótese de uma mutação C282Y de novo no gene HFE associada ao haplótipo HLA-A*24-B*15. Em conclusão, além do haplótipo ancestral A*03-B*07, três novos haplótipos – A*02-B*58, A*24-B*15 e A*29-B*45 – sugerem estar associados à mutação C282Y na população da ilha de São Miguel. A elevada diversidade genética observada na população açoriana pode explicar a associação entre a mutação C282Y e os haplótipos HLA.Hereditary hemochromatosis is an autosomal recessive disease of the iron metabolism, where HFE C282Y is commonly implicated. This mutation seems to have originated by chance on the HLA-A*03-B*07 haplotype in a northwestern European individual, and spread by migration. Given that recombination generates new haplotypes, the present investigation aimed to characterize the chromosomal background of C282Y in the São Miguel Island population (Azores). This study comprises 130 individuals, all negative for H63D and S65C, which were classified into two groups: 48 homozygous or carriers for C282Y, and 82 healthy individuals without these mutations. The subjects were HLA-A and -B genotyped by PCR-SSP, and HFE mutation detection was performed by PCR-RFLP. Statistical analysis revealed that four alleles – A*03 (p=0.003, OR=3.33), A*26 (p=0.003, OR=8.38), A*29 (p<0.001, OR=19.18) and B*45 (p=0.003 OR=8.37) – and the A*03-B*07 haplotype (p=0.006, OR=8.96) were significantly increased in the C282Y group. Two non-ancestral haplotypes were also significantly associated with C282Y: A*02-B*58 (p<0.001, OR=19.78) and A*29-B*45 (p<0.001, OR=27.57). This last haplotype showed the strongest association to the mutation in study, suggesting that it may be the principal hemochromatosis-haplotype in São Miguel Island population. Another haplotype – A*24-B*15 – was detected by direct inference in a C282Y and HLA-A-B homozygous patient. Recombination most probably generated these haplotypes, before or after the island settlement. However, we can not exclude the hypothesis of a recent de novo HFE C282Y mutation on the A*24-B*15 haplotype in an individual living in the São Miguel Island. Overall, in this population, besides the ancestral A*03-B*07, three new non-ancestral haplotypes – A*02-B*58, A*24-B*15 and A*29-B*45 – appear to be associated with C282Y. The association between this recessive mutation and these haplotypes undoubtedly reflects the high genetic diversity observed in the Azoreans

    Bienestar del búfalo de agua, bovino europeo y bovino índico en respuesta a la sombra natural y artificial: aspectos medioambientales, fisiológicos y conductuales

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    Uno de los principales retos dentro de los sistemas de producción de los Bovidae, búfalo de agua (Bubalus bubalis), Bovino Europeo (Bos taurus) y Bovino Índico (Bos indicus) es el incremento en la temperatura ambiental por efecto del cambio climático (Mota-Rojas et al., 2021a,b,c,d; Mota-Rojas et al., 2022a,b; Napolitano et al., 2023a,b). El término estrés describe los cambios fisiológicos y de comportamiento de un organismo con el fin de regresar a la homeostasis (Manteca et al., 2013; Mota-Rojas et al., 2019a,b,c; Mota-Rojas et al., 2020a,b; Napolitano et al., 2020; 2022). Aunque dichos cambios se pueden considerar adaptaciones con beneficios hacia los animales (Guerrero-Legarreta et al., 2019; MotaRojas et al., 2019a,b,c; Mota-Rojas et al., 2020a,b), cuando se mantienen por periodos prolongados de tiempo conllevan repercusiones en la producción, salud y bienestar de los bovinos (Le Fevre et al., 2003; St-Pierre et al., 2003; Brown y Vosloo, 2017; Foust y Headlee, 2017).Fil: Mota Rojas, Daniel. Universidad Autónoma Metropolitana; MéxicoFil: Habeeb, Alsaied Alnaimy. Egyptian Atomic Energy Authority. Nuclear Research Center; EgiptoFil: Napolitano, Fabio. Università degli Studi della Basillicata; ItaliaFil: Sarubbi, Juliana. Universidade Federal de Santa Maria; BrasilFil: Ghezzi, Marcelo Daniel. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias. Departamento de Ciencias Biológicas; ArgentinaFil: Ceriani, Maria Carolina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Cuibus, Alex. University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca; RumaniaFil: Braghieri, Ada. Università degli Studi della Basillicata; ItaliaFil: Lendez, Pamela Anahí. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tandil. Centro de Investigación Veterinaria de Tandil. Universidad Nacional del Centro de la Provincia de Buenos Aires. Centro de Investigación Veterinaria de Tandil. Provincia de Buenos Aires. Gobernación. Comision de Investigaciones Científicas. Centro de Investigación Veterinaria de Tandil; Argentina. Universidad Nacional del Centro de la Provincia de Buenos Aires. Facultad de Ciencias Veterinarias; ArgentinaFil: Martínez, Gabriela Marcela. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Salta. Estación Experimental Agropecuaria Salta; ArgentinaFil: Domínguez, Adriana. Universidad Autónoma Metropolitana; MéxicoFil: Bragaglio, Andrea. Research Centre for Engineering and Food Processing; ItaliaFil: Ravikanth Reddy, Poonooru. Animal Husbandry Department; Indi

    THE USE of CONSORTIA for the INTERNATIONALIZATION of FIRMS – MOTA-ENGIL CASE STUDY

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    Internationalization has been widely studied throughout the years. Broadly, it has been predicted as irrevocable and having increasing impact on firm-related strategy. Within entry modes, consortium, has not received as much attention as others. Hence, it seems important to understand how this specific entry mode allows the entrance of firms in the international markets. This study intends to answer the question of “how” to internationalize, anticipating the consortium as the most feasible way for construction firms to enter certain markets. The reasons that determine its choice concern the specificness of the projects, markets and of the firm. In the first part of the study, we review the existent literature on consortia as an entry mode and as a tool of internationalization used by construction firms. Through this review we build a framework that reveals the motivations that lead to this choice. In the second part, we present the case study of Mota-Engil, as a potential source of valuable information which may contribute to the understanding of the phenomenon under study. This case study corroborates the motivations found to create consortia. The paper closes with its contributions, limitations and suggestions for future researches.consortia, internationalization, cooperation, construction

    El parto y ordeño de la búfala : respuestas fisiológicas y conductuales

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    El éxito en los sistemas productivos se puede medir por el nacimiento de crías. Generalmente las búfalas de agua (Bubalus bubalis) paren al año un único ternero, y excepcionalmente nacen gemelos (De Rosa et al., 2009a). Se debe hacer énfasis en que durante la gestación suceden cambios anatómicos y fisiológicos en la hembra asociados al crecimiento del feto por 300 a 310 días aproximadamente (Punia y Singh, 2001). Al contrario, el parto es un evento donde ocurren cambios fisiológicos y morfológicos bruscos, severos y relativamente rápidos (Mota-Rojas et al., 2008), con la presencia de un cierto grado de dolor dando origen a estrés y ansiedad (Pereira et al., 2011; Mota-Rojas, 2019a,b; Napolitano et al., 2018a,b; Napolitano et al., 2020a,b; Mota-Rojas et al., 2020a)

    Amino acid alignment of MotA.

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    <p>The <i>motA</i> mutations are predicted to result in non-functional proteins. A missense mutation at base 262 (T1, Type B) resulted in an A to P mutation at amino acid 88; a nonsense mutation at base 612 (T3, Type D) resulted in a premature truncation; a duplication of 49 bp created a direct repeat within <i>motA</i> and led to the replacement of the last 73 residues in the C-terminus with a sequence of 39 new residues that are highlighted (T108, Type C); and a deletion at base 64 resulting in a truncated protein (T158, Type A).</p

    H.E. Mr. Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil

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    Photo 01: On the surface at the LHCb pit, H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil (centre) with from left to right G. Carboni, C. Melo, J. Ellis, J.A. Rubio, T. Nakada, B. Maréchal, R. Lindner. Photo 02: On the surface at the LHCb pit, H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil (left) with from left to right, C. Melo, B. Schmidt, B. Maréchal, G. Carboni. Photo 03: On the surface at the LHCb pit, H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil inspecting an electronic sample. Photo 04: In the LHCb cavern H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil (third from left) with from left to right C. Melo, B. Maréchal, T. Nakada, B. Schmidt, W. Riegler, G. Carboni, R. Lindner. Photo 05: In the LHCb cavern H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil (third from left) with from left to right C. Melo, B. Maréchal, T. Nakada, B. Schmidt, W. Riegler, G. Carboni, R. Lindner. Photo 06: In the LHCb cavern H.E. Mr Ronaldo Mota Sardenberg, Minister for Science, Technology and Innovation, Brazil (fourth from left) J.A. Rubio, B. Maréchal, C. Melo, T. Nakada, B. Schmidt, W. Riegler, G. Carboni, A. Santoro, R. Lindner, R. Salmeron, J.G. Kadri, O. Vieira
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