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    EFFETTI EMODINAMICI SUL CIRCOLO POLMONARE DOPO SOMMINISTRAZIONE ENDOVENA DI DILTIAZEM

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    Five patients with diagnosis of pulmonary hypertension secondary to chronic obstructive pulmonary disease were studied acutely to assess the effects of a vasodilator, Diltiazem, on central hemodynamic function. Diltiazem is a member of the class of pharmacologic agents known as calcium antagonist. The drug was administered IV by continuous infusion at 0.22 mg/Kg. Hemodynamic measurements were performed by a Swan-Ganz catheter. Diltiazem had no value in reversing high pulmonary artery pressures and resistances, but the vasodilator therapy had a greater effect on systemic vasculature. -------------------------------------------------------------------------------- Reaxys Database Information| -------------------------------------------------------------------------------

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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